 Capsid
"Capsid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The outer protein protective shell of a virus, which protects the viral nucleic acid.
| Descriptor ID |
D002213
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| MeSH Number(s) |
A21.249.500.250 B04.950.500.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Capsid".
Below are MeSH descriptors whose meaning is more specific than "Capsid".
This graph shows the total number of publications written about "Capsid" by people in this website by year, and whether "Capsid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 3 | 0 | 3 | | 1997 | 0 | 1 | 1 | | 2000 | 2 | 1 | 3 | | 2001 | 1 | 2 | 3 | | 2002 | 2 | 0 | 2 | | 2003 | 2 | 2 | 4 | | 2004 | 1 | 0 | 1 | | 2007 | 1 | 2 | 3 | | 2011 | 1 | 0 | 1 | | 2012 | 3 | 1 | 4 | | 2013 | 2 | 2 | 4 | | 2014 | 3 | 0 | 3 | | 2016 | 1 | 2 | 3 | | 2017 | 1 | 2 | 3 | | 2018 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2020 | 2 | 2 | 4 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 2 | 3 | | 2023 | 1 | 2 | 3 | | 2024 | 2 | 2 | 4 | | 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Capsid" by people in Profiles.
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Briganti L, Annamalai AS, Bester SM, Wei G, Andino-Moncada JR, Singh SP, Kleinpeter AB, Tripathi M, Nguyen B, Radhakrishnan R, Singh PK, Greenwood J, Schope LI, Haney R, Huang S-W, Freed EO, Engelman AN, Francis AC, Kvaratskhelia M. Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir. mBio. 2025 May 14; 16(5):e0361324.
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Flick H, Venbakkam A, Singh PK, Layish B, Huang S-W, Radhakrishnan R, Kvaratskhelia M, Engelman AN, Kane M. Interplay between the cyclophilin homology domain of RANBP2 and MX2 regulates HIV-1 capsid dependencies on nucleoporins. mBio. 2025 Mar 12; 16(3):e0264624.
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Pra??k V, Mironova Y, Vasishtan D, Hagen C, Laugks U, Jensen Y, Sanders S, Heumann JM, Bosse JB, Klupp BG, Mettenleiter TC, Grange M, Gr?newald K. Molecular plasticity of herpesvirus nuclear egress analysed in situ. Nat Microbiol. 2024 Jul; 9(7):1842-1855.
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Layish B, Goli R, Flick H, Huang SW, Zhang RZ, Kvaratskhelia M, Kane M. Virus specificity and nucleoporin requirements for MX2 activity are affected by GTPase function and capsid-CypA interactions. PLoS Pathog. 2024 Mar; 20(3):e1011830.
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Xu J, Erlendsson S, Singh M, Holling GA, Regier M, Ibiricu I, Einstein J, Hantak MP, Day GS, Piquet AL, Smith TL, Clardy SL, Whiteley AM, Feschotte C, Briggs JAG, Shepherd JD. PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome. Cell. 2024 Feb 15; 187(4):831-845.e19.
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Gifford LB, Melikyan GB. HIV-1 Capsid Uncoating Is a Multistep Process That Proceeds through Defect Formation Followed by Disassembly of the Capsid Lattice. ACS Nano. 2024 01 30; 18(4):2928-2947.
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Gaurav N, Kumar S, Raghavendhar S, Tripathi PK, Gupta S, Arya R, Patel AK. Transcriptome analysis of Huh7 cells upon Chikungunya virus infection and capsid transfection reveals regulation of distinct cellular and metabolic pathways. Virology. 2024 01; 589:109953.
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Coleman H, Saylor Perez J, Schwartz DK, Kaar J, Garcea RL, Randolph TW. Effect of mechanical stresses on viral capsid disruption during droplet formation and drying. Colloids Surf B Biointerfaces. 2024 Jan; 233:113661.
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Xue G, Yu HJ, Buffone C, Huang SW, Lee K, Goh SL, Gres AT, Guney MH, Sarafianos SG, Luban J, Diaz-Griffero F, KewalRamani VN. The HIV-1 capsid core is an opportunistic nuclear import receptor. Nat Commun. 2023 06 24; 14(1):3782.
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Bester SM, Adu-Ampratwum D, Annamalai AS, Wei G, Briganti L, Murphy BC, Haney R, Fuchs JR, Kvaratskhelia M. Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir. mBio. 2022 10 26; 13(5):e0180422.
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