 Virulence
"Virulence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
| Descriptor ID |
D014774
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| MeSH Number(s) |
G06.930
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Virulence".
Below are MeSH descriptors whose meaning is more specific than "Virulence".
This graph shows the total number of publications written about "Virulence" by people in this website by year, and whether "Virulence" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 4 | 4 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 4 | 4 | | 2002 | 0 | 9 | 9 | | 2003 | 1 | 5 | 6 | | 2004 | 0 | 8 | 8 | | 2005 | 0 | 4 | 4 | | 2006 | 0 | 4 | 4 | | 2007 | 3 | 4 | 7 | | 2008 | 0 | 8 | 8 | | 2009 | 0 | 5 | 5 | | 2010 | 0 | 7 | 7 | | 2011 | 1 | 11 | 12 | | 2012 | 2 | 8 | 10 | | 2013 | 0 | 8 | 8 | | 2014 | 0 | 10 | 10 | | 2015 | 0 | 8 | 8 | | 2016 | 3 | 6 | 9 | | 2017 | 0 | 12 | 12 | | 2018 | 1 | 7 | 8 | | 2019 | 1 | 9 | 10 | | 2020 | 0 | 13 | 13 | | 2021 | 2 | 5 | 7 | | 2022 | 0 | 6 | 6 | | 2023 | 0 | 7 | 7 | | 2024 | 0 | 7 | 7 | | 2025 | 0 | 7 | 7 | | 2026 | 0 | 6 | 6 |
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Below are the most recent publications written about "Virulence" by people in Profiles.
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Detweiler CS, Alav I. How resistance-nodulation-division (RND) efflux pumps contribute to virulence. PLoS Pathog. 2026 05; 22(5):e1014228.
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Shapiro BL, Jaiswal P, Funkhouser-Jones LJ, Roy S, Van Gundy TJ, Bono JM, Lybecker MC, Garcia BL, Hyde JA, Skare JT. The Borreliella burgdorferi BosR-associated small non-coding RNA BasA regulates virulence. Infect Immun. 2026 Apr 15; 94(4):e0002626.
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John MS, Chinnappan M, Sturges CI, Artami M, Bhattacharya M, Keogh RA, Kavanaugh JS, Jain S, Gedamu H, Komarovsky J, Velasquez M, Sharma T, McDonald JG, Horswill AR, Harris-Tryon TA. Skin androgens regulate Staphylococcus aureus pathogenicity via quorum sensing. Nat Microbiol. 2026 Mar; 11(3):704-717.
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Anderson CM, Wilkening RV, Boulos S, Keys TG, Ebert M-O, Zinsli LV, Krusche J, Loessner MJ, Feldstein SF, Chang JC, Peschel A, Horswill AR, Shen Y, Federle MJ. A teichoic acid-like wall modification associated with immune suppression is socially regulated in Streptococcus pyogenes. mBio. 2026 Apr 08; 17(4):e0380125.
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Penaranda C, Brenner EP, Clatworthy AE, Cosimi LA, Ravi J, Hung DT. Genomic comparison and phenotypic characterization of Pseudomonas aeruginosa isolates across environmental and diverse clinical isolation sites. mSystems. 2026 Mar 24; 11(3):e0136225.
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Pershing NL, Brzozowski RS, Schmidt AK, Faith DR, Joyce AC, de Ora LO, Kominsky JD, Dankwardt A, Maciver A, Bell R, Henriques WS, Andersen SE, Wiedenheft B, Casjens SR, Duerkop BA, Round JL, Secor PR. A prophage-encoded sRNA limits phage infection of adherent-invasive E. coli. PLoS Pathog. 2026 Jan; 22(1):e1013836.
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Margolis A, Liu L, Kim J-S, Porwollik S, McClelland M, Vázquez-Torres A. Amino acid decarboxylation preserves Salmonella fitness during phagocyte-derived oxidative stress. mBio. 2026 Jan 14; 17(1):e0314725.
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Detweiler CS, Alav I. Beyond antibiotic resistance: evidence for resistance-nodulation-division (RND) efflux pumps as virulence determinants. Microbiol Mol Biol Rev. 2025 Dec 18; 89(4):e0027824.
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Lurie-Weinberger MN, Cohen A, Kon H, Kastel O, Keren-Paz A, Schwartz D, Lellouche J, Nutman A, Frenk S, Schechner V, Temkin E, Friberg LE, Daikos GL, Skiada A, Durante-Mangoni E, Yahav D, Leibovici L, Dickstein Y, Dishon Benattar Y, Paul M, Carmeli Y. Virulence factors are preserved within carbapenem-resistant Acinetobacter baumannii clades. Virulence. 2025 Dec; 16(1):2542489.
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Raab JE, Harju TB, Toperzer JD, Duncan-Lowey JK, Thomas CI, Darehshouri A, Goldberg MB, Russo BC. A translocation-competent pore is required for Shigella flexneri to escape from the double membrane vacuole during intercellular spread. mBio. 2025 Sep 10; 16(9):e0167425.
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