Virulence
"Virulence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
| Descriptor ID |
D014774
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| MeSH Number(s) |
G06.930
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Virulence".
Below are MeSH descriptors whose meaning is more specific than "Virulence".
This graph shows the total number of publications written about "Virulence" by people in this website by year, and whether "Virulence" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 4 | 4 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 4 | 4 | | 2002 | 0 | 9 | 9 | | 2003 | 1 | 5 | 6 | | 2004 | 0 | 8 | 8 | | 2005 | 0 | 4 | 4 | | 2006 | 0 | 4 | 4 | | 2007 | 3 | 4 | 7 | | 2008 | 0 | 8 | 8 | | 2009 | 0 | 5 | 5 | | 2010 | 0 | 8 | 8 | | 2011 | 1 | 11 | 12 | | 2012 | 2 | 8 | 10 | | 2013 | 0 | 8 | 8 | | 2014 | 0 | 10 | 10 | | 2015 | 0 | 8 | 8 | | 2016 | 3 | 6 | 9 | | 2017 | 0 | 12 | 12 | | 2018 | 1 | 7 | 8 | | 2019 | 1 | 9 | 10 | | 2020 | 0 | 13 | 13 | | 2021 | 2 | 5 | 7 | | 2022 | 0 | 5 | 5 | | 2023 | 0 | 7 | 7 | | 2024 | 0 | 7 | 7 | | 2025 | 0 | 6 | 6 | | 2026 | 0 | 2 | 2 |
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Below are the most recent publications written about "Virulence" by people in Profiles.
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Penaranda C, Brenner EP, Clatworthy AE, Cosimi LA, Ravi J, Hung DT. Genomic comparison and phenotypic characterization of Pseudomonas aeruginosa isolates across environmental and diverse clinical isolation sites. mSystems. 2026 Mar 24; 11(3):e0136225.
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Pershing NL, Brzozowski RS, Schmidt AK, Faith DR, Joyce AC, de Ora LO, Kominsky JD, Dankwardt A, Maciver A, Bell R, Henriques WS, Andersen SE, Wiedenheft B, Casjens SR, Duerkop BA, Round JL, Secor PR. A prophage-encoded sRNA limits phage infection of adherent-invasive E. coli. PLoS Pathog. 2026 Jan; 22(1):e1013836.
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Detweiler CS, Alav I. Beyond antibiotic resistance: evidence for resistance-nodulation-division (RND) efflux pumps as virulence determinants. Microbiol Mol Biol Rev. 2025 Dec 18; 89(4):e0027824.
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Lurie-Weinberger MN, Cohen A, Kon H, Kastel O, Keren-Paz A, Schwartz D, Lellouche J, Nutman A, Frenk S, Schechner V, Temkin E, Friberg LE, Daikos GL, Skiada A, Durante-Mangoni E, Yahav D, Leibovici L, Dickstein Y, Dishon Benattar Y, Paul M, Carmeli Y. Virulence factors are preserved within carbapenem-resistant Acinetobacter baumannii clades. Virulence. 2025 Dec; 16(1):2542489.
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Raab JE, Harju TB, Toperzer JD, Duncan-Lowey JK, Thomas CI, Darehshouri A, Goldberg MB, Russo BC. A translocation-competent pore is required for Shigella flexneri to escape from the double membrane vacuole during intercellular spread. mBio. 2025 Sep 10; 16(9):e0167425.
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Tran SL, Lebreuilly L, Cormontagne D, Samson S, Tô TB, Stosskopf M, Dervyn R, Grießhammer A, de la Cuesta-Zuluaga J, Maier L, Naas T, Mura S, Rognan D, Nicolas J, André G, Ramarao N. An anti-virulence drug targeting the evolvability protein Mfd protects against infections with antimicrobial resistant ESKAPE pathogens. Nat Commun. 2025 Apr 28; 16(1):3324.
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Enroth TJ, Severn MM, Costa FG, Bovee AR, Wilkening RV, Nguyen DT, Langouët-Astrié C, Horswill AR. Global changes in Staphylococcus aureus virulence and metabolism during colonization of healthy skin. Infect Immun. 2025 04 08; 93(4):e0002825.
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Akbari MS, Joyce LR, Spencer BL, Brady A, McIver KS, Doran KS. Identification of glyoxalase A in group B Streptococcus and its contribution to methylglyoxal tolerance and virulence. Infect Immun. 2025 04 08; 93(4):e0054024.
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Rakibova Y, Dunham DT, Seed KD, Freddolino L. Nucleoid-associated proteins shape the global protein occupancy and transcriptional landscape of a clinical isolate of Vibrio cholerae. mSphere. 2024 Jul 30; 9(7):e0001124.
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Leser JS, Frost JL, Wilson CJ, Rudy MJ, Clarke P, Tyler KL. VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis. J Virol. 2024 07 23; 98(7):e0039724.
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