 Follicle Stimulating Hormone, beta Subunit
"Follicle Stimulating Hormone, beta Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The beta subunit of follicle stimulating hormone. It is a 15-kDa glycopolypeptide. Full biological activity of FSH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the FSHB gene causes delayed puberty, or infertility.
| Descriptor ID |
D037201
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| MeSH Number(s) |
D06.472.699.322.576.288.500 D06.472.699.631.525.343.288.500 D12.644.548.691.525.343.288.500
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| Concept/Terms |
Follicle Stimulating Hormone, beta Subunit- Follicle Stimulating Hormone, beta Subunit
- Follicle-Stimulating Hormone, beta Subunit
- FSH, beta Subunit
- FSH-beta
- FSH beta
- Follicle Stimulating Hormone, beta Polypeptide Chain
- FSH, beta Chain
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Below are MeSH descriptors whose meaning is more general than "Follicle Stimulating Hormone, beta Subunit".
- Chemicals and Drugs [D]
- Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
- Peptide Hormones [D06.472.699]
- Gonadotropins [D06.472.699.322]
- Gonadotropins, Pituitary [D06.472.699.322.576]
- Follicle Stimulating Hormone [D06.472.699.322.576.288]
- Follicle Stimulating Hormone, beta Subunit [D06.472.699.322.576.288.500]
- Pituitary Hormones [D06.472.699.631]
- Pituitary Hormones, Anterior [D06.472.699.631.525]
- Gonadotropins, Pituitary [D06.472.699.631.525.343]
- Follicle Stimulating Hormone [D06.472.699.631.525.343.288]
- Follicle Stimulating Hormone, beta Subunit [D06.472.699.631.525.343.288.500]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Peptide Hormones [D12.644.548]
- Pituitary Hormones [D12.644.548.691]
- Pituitary Hormones, Anterior [D12.644.548.691.525]
- Gonadotropins, Pituitary [D12.644.548.691.525.343]
- Follicle Stimulating Hormone [D12.644.548.691.525.343.288]
- Follicle Stimulating Hormone, beta Subunit [D12.644.548.691.525.343.288.500]
Below are MeSH descriptors whose meaning is more specific than "Follicle Stimulating Hormone, beta Subunit".
This graph shows the total number of publications written about "Follicle Stimulating Hormone, beta Subunit" by people in this website by year, and whether "Follicle Stimulating Hormone, beta Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2001 | 0 | 2 | 2 | | 2003 | 4 | 0 | 4 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 3 | 1 | 4 | | 2009 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Follicle Stimulating Hormone, beta Subunit" by people in Profiles.
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Kumar TR. Rerouting of follicle-stimulating hormone secretion and gonadal function. Fertil Steril. 2023 02; 119(2):180-183.
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Ongaro L, Schang G, Zhou Z, Kumar TR, Treier M, Deng CX, Boehm U, Bernard DJ. Human Follicle-Stimulating Hormone ? Subunit Expression Depends on FOXL2 and SMAD4. Endocrinology. 2020 05 01; 161(5).
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Roy S, Gandra D, Seger C, Biswas A, Kushnir VA, Gleicher N, Kumar TR, Sen A. Oocyte-Derived Factors (GDF9 and BMP15) and FSH Regulate AMH Expression Via Modulation of H3K27AC in Granulosa Cells. Endocrinology. 2018 09 01; 159(9):3433-3445.
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Liu P, Ji Y, Yuen T, Rendina-Ruedy E, DeMambro VE, Dhawan S, Abu-Amer W, Izadmehr S, Zhou B, Shin AC, Latif R, Thangeswaran P, Gupta A, Li J, Shnayder V, Robinson ST, Yu YE, Zhang X, Yang F, Lu P, Zhou Y, Zhu LL, Oberlin DJ, Davies TF, Reagan MR, Brown A, Kumar TR, Epstein S, Iqbal J, Avadhani NG, New MI, Molina H, van Klinken JB, Guo EX, Buettner C, Haider S, Bian Z, Sun L, Rosen CJ, Zaidi M. Blocking FSH induces thermogenic adipose tissue and reduces body fat. Nature. 2017 06 01; 546(7656):107-112.
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Wang H, May J, Butnev V, Shuai B, May JV, Bousfield GR, Kumar TR. Evaluation of in?vivo bioactivities of recombinant hypo- (FSH21/18) and fully- (FSH24) glycosylated human FSH glycoforms in Fshb null mice. Mol Cell Endocrinol. 2016 12 05; 437:224-236.
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Wang H, Butnev V, Bousfield GR, Kumar TR. A human FSHB transgene encoding the double N-glycosylation mutant (Asn(7?) Asn(24?)) FSH? subunit fails to rescue Fshb null mice. Mol Cell Endocrinol. 2016 May 05; 426:113-24.
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Wang H, Hastings R, Miller WL, Kumar TR. Fshb-iCre mice are efficient and specific Cre deleters for the gonadotrope lineage. Mol Cell Endocrinol. 2016 Jan 05; 419:124-38.
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Kumar TR. FSHbeta knockout mouse model: a decade ago and into the future. Endocrine. 2009 Aug; 36(1):1-5.
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Iqbal J, Sun L, Kumar TR, Blair HC, Zaidi M. Follicle-stimulating hormone stimulates TNF production from immune cells to enhance osteoblast and osteoclast formation. Proc Natl Acad Sci U S A. 2006 Oct 03; 103(40):14925-30.
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Zhang L, Kessler AE, Tsai PS. Characterization and steroidal regulation of gonadotropin beta subunits in the male leopard frog, Rana pipiens. Gen Comp Endocrinol. 2007 Jan 01; 150(1):66-74.
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