 Pyrrolizidine Alkaloids
"Pyrrolizidine Alkaloids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.
| Descriptor ID |
D011763
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| MeSH Number(s) |
D03.132.716 D03.633.100.772
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrrolizidine Alkaloids".
Below are MeSH descriptors whose meaning is more specific than "Pyrrolizidine Alkaloids".
This graph shows the total number of publications written about "Pyrrolizidine Alkaloids" by people in this website by year, and whether "Pyrrolizidine Alkaloids" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyrrolizidine Alkaloids" by people in Profiles.
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Jahouh F, Marongiu F, Serra MP, Laconi E, Banoub J. Gas-phase fragmentation of the N-oxide and N-hydroxylated derivatives of retrorsine using liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Rapid Commun Mass Spectrom. 2015 Oct 15; 29(19):1733-48.
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Singer MS, Mason PA, Smilanich AM. Ecological immunology mediated by diet in herbivorous insects. Integr Comp Biol. 2014 Nov; 54(5):913-21.
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Marongiu F, Serra MP, Sini M, Marongiu M, Contini A, Laconi E. Cell turnover in the repopulated rat liver: distinct lineages for hepatocytes and the biliary epithelium. Cell Tissue Res. 2014 May; 356(2):333-40.
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Serra MP, Marongiu F, Sini M, Laconi E. Hepatocyte senescence in vivo following preconditioning for liver repopulation. Hepatology. 2012 Aug; 56(2):760-8.
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Serra MP, Doratiotto S, Marongiu F, Laconi E. Normal hepatocyte transplantation delays the emergence of chemically induced preneoplastic nodules in rat liver. Cell Transplant. 2012; 21(4):671-7.
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Doratiotto S, Krause P, Serra MP, Marongiu F, Sini M, Koenig S, Laconi E. The growth pattern of transplanted normal and nodular hepatocytes. Histochem Cell Biol. 2011 Jun; 135(6):581-91.
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Alali FQ, Tahboub YR, Ibrahim ES, Qandil AM, Tawaha K, Burgess JP, Sy A, Nakanishi Y, Kroll DJ, Oberlies NH. Pyrrolizidine alkaloids from Echium glomeratum (Boraginaceae). Phytochemistry. 2008 Sep; 69(12):2341-6.
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Fasules JW, Stenmark KR, Henson PM, Voelkel NF, Reeves JT. Neither anticoagulant nor nonanticoagulant heparin affects monocrotaline lung injury. J Appl Physiol (1985). 1987 Feb; 62(2):816-20.
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Gillespie MN, Olson JW, Reinsel CN, O'Connor WN, Altiere RJ. Vascular hyperresponsiveness in perfused lungs from monocrotaline-treated rats. Am J Physiol. 1986 Jul; 251(1 Pt 2):H109-14.
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Altiere RJ, Olson JW, Gillespie MN. Altered pulmonary vascular smooth muscle responsiveness in monocrotaline-induced pulmonary hypertension. J Pharmacol Exp Ther. 1986 Feb; 236(2):390-5.
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