 Cyclin-Dependent Kinase Inhibitor p15
"Cyclin-Dependent Kinase Inhibitor p15" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An INK4 cyclin-dependent kinase inhibitor containing four ANKYRIN-LIKE REPEATS. INK4B is often inactivated by deletions, mutations, or hypermethylation in HEMATOLOGIC NEOPLASMS.
| Descriptor ID |
D050762
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| MeSH Number(s) |
D12.644.360.225.100 D12.776.167.187.100 D12.776.476.225.100 D12.776.624.776.355.100
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| Concept/Terms |
Cyclin-Dependent Kinase Inhibitor p15- Cyclin-Dependent Kinase Inhibitor p15
- Cyclin Dependent Kinase Inhibitor p15
- INK4B Protein
- CDKN2B Protein
- INK4b Cyclin-Dependent Kinase Inhibitor
- INK4b Cyclin Dependent Kinase Inhibitor
- p15INK4B Protein
- p15 CDK4 Inhibitor
- CDK4 Inhibitor, p15
- Cyclin-Dependent Kinase Inhibitor 2B
- Cyclin Dependent Kinase Inhibitor 2B
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Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase Inhibitor p15".
Below are MeSH descriptors whose meaning is more specific than "Cyclin-Dependent Kinase Inhibitor p15".
This graph shows the total number of publications written about "Cyclin-Dependent Kinase Inhibitor p15" by people in this website by year, and whether "Cyclin-Dependent Kinase Inhibitor p15" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclin-Dependent Kinase Inhibitor p15" by people in Profiles.
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Deng MY, Sturm D, Pfaff E, Sill M, Stichel D, Balasubramanian GP, Tippelt S, Kramm C, Donson AM, Green AL, Jones C, Schittenhelm J, Ebinger M, Schuhmann MU, Jones BC, van Tilburg CM, Wittmann A, Golanov A, Ryzhova M, Ecker J, Milde T, Witt O, Sahm F, Reuss D, Sumerauer D, Zamecnik J, Korshunov A, von Deimling A, Pfister SM, Jones DTW. Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B. Nat Commun. 2021 09 20; 12(1):5530.
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Laetsch TW, Roy A, Xu L, Black JO, Coffin CM, Chi YY, Tian J, Spunt SL, Hawkins DS, Bridge JA, Parsons DW, Skapek SX. Undifferentiated Sarcomas in Children Harbor Clinically Relevant Oncogenic Fusions and Gene Copy-Number Alterations: A Report from the Children's Oncology Group. Clin Cancer Res. 2018 08 15; 24(16):3888-3897.
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Sikka A, Kaur M, Agarwal C, Deep G, Agarwal R. Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation. Cell Cycle. 2012 Apr 01; 11(7):1374-82.
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Bjerke GA, Hyman-Walsh C, Wotton D. Cooperative transcriptional activation by Klf4, Meis2, and Pbx1. Mol Cell Biol. 2011 Sep; 31(18):3723-33.
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Kral BG, Mathias RA, Suktitipat B, Ruczinski I, Vaidya D, Yanek LR, Quyyumi AA, Patel RS, Zafari AM, Vaccarino V, Hauser ER, Kraus WE, Becker LC, Becker DM. A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry. J Hum Genet. 2011 Mar; 56(3):224-9.
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Dougherty MJ, Wilmoth DM, Tooke LS, Shaikh TH, Gai X, Hakonarson H, Biegel JA. Implementation of high resolution single nucleotide polymorphism array analysis as a clinical test for patients with hematologic malignancies. Cancer Genet. 2011 Jan; 204(1):26-38.
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Pacheco TR, Maxwell F, Vasiloudes PE, Robinson WA, Norris DA, Maxwell IH. Positive tetracycline control of expression of p15INK4B from an Epstein-Barr autonomous plasmid in a human melanoma cell line. Gene. 2000 Jan 25; 242(1-2):249-56.
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Maloney KW, McGavran L, Odom LF, Hunger SP. Acquisition of p16(INK4A) and p15(INK4B) gene abnormalities between initial diagnosis and relapse in children with acute lymphoblastic leukemia. Blood. 1999 Apr 01; 93(7):2380-5.
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Maloney KW, McGavran L, Odom LF, Hunger SP. Different patterns of homozygous p16INK4A and p15INK4B deletions in childhood acute lymphoblastic leukemias containing distinct E2A translocations. Leukemia. 1998 Sep; 12(9):1417-21.
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Maloney KW, Rubnitz JE, Cleary ML, Frankel LS, Hakami N, Link MP, Pullen DJ, Hunger SP. Lack of ETV6 (TEL) gene rearrangements or p16INK4A/p15INK4B homozygous gene deletions in infant acute lymphoblastic leukemia. Leukemia. 1997 Jul; 11(7):979-83.
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