rhoC GTP-Binding Protein
"rhoC GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rho GTP-binding protein that is prenylated (see PROTEIN PRENYLATION) at its C-terminus and cycles between the cytoplasm and plasma membrane, linking receptor signaling pathways with assembly of FOCAL ADHESIONS; STRESS FIBERS; and contractile ring formation during CYTOKINESIS. It is overexpressed in proliferating and metastatic tumor cells.
Descriptor ID |
D000075024
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MeSH Number(s) |
D08.811.277.040.330.300.400.700.650 D12.644.360.525.700.650 D12.776.157.325.515.700.650 D12.776.476.525.700.650
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Concept/Terms |
rhoC GTP-Binding Protein- rhoC GTP-Binding Protein
- GTP-Binding Protein, rhoC
- rhoC GTP Binding Protein
- rhoC GTPase
- ras Homolog Family Member C
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Below are MeSH descriptors whose meaning is more general than "rhoC GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "rhoC GTP-Binding Protein".
This graph shows the total number of publications written about "rhoC GTP-Binding Protein" by people in this website by year, and whether "rhoC GTP-Binding Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "rhoC GTP-Binding Protein" by people in Profiles.
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Griner EM, Dancik GM, Costello JC, Owens C, Guin S, Edwards MG, Brautigan DL, Theodorescu D. RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer. Mol Cancer Res. 2015 Mar; 13(3):483-92.
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Nakayama I, Shibazaki M, Yashima-Abo A, Miura F, Sugiyama T, Masuda T, Maesawa C. Loss of HOXD10 expression induced by upregulation of miR-10b accelerates the migration and invasion activities of ovarian cancer cells. Int J Oncol. 2013 Jul; 43(1):63-71.
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Ruth MC, Xu Y, Maxwell IH, Ahn NG, Norris DA, Shellman YG. RhoC promotes human melanoma invasion in a PI3K/Akt-dependent pathway. J Invest Dermatol. 2006 Apr; 126(4):862-8.
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Nusrat A, Giry M, Turner JR, Colgan SP, Parkos CA, Carnes D, Lemichez E, Boquet P, Madara JL. Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia. Proc Natl Acad Sci U S A. 1995 Nov 07; 92(23):10629-33.
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