 Theophylline
"Theophylline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
| Descriptor ID |
D013806
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| MeSH Number(s) |
D03.132.960.751 D03.633.100.759.758.824.751
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| Concept/Terms |
Theophylline- Theophylline
- 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- 1,3-Dimethylxanthine
- 1,3 Dimethylxanthine
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Below are MeSH descriptors whose meaning is more general than "Theophylline".
Below are MeSH descriptors whose meaning is more specific than "Theophylline".
This graph shows the total number of publications written about "Theophylline" by people in this website by year, and whether "Theophylline" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1995 | 1 | 1 | 2 | | 1996 | 1 | 2 | 3 | | 1999 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 2 | 3 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Theophylline" by people in Profiles.
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Shakowski C, Pham VA, Raines J, Quaife RA, Page RL. Safety and efficacy of IV theophylline for regadenoson-associated side effect reversal. J Nucl Cardiol. 2023 04; 30(2):585-589.
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Frymoyer A, Van Meurs KP, Drover DR, Klawitter J, Christians U, Chock VY. Theophylline dosing and pharmacokinetics for renal protection in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia. Pediatr Res. 2020 12; 88(6):871-877.
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Xie AX, Madayag A, Minton SK, McCarthy KD, Malykhina AP. Sensory satellite glial Gq-GPCR activation alleviates inflammatory pain via peripheral adenosine 1 receptor activation. Sci Rep. 2020 08 25; 10(1):14181.
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Iwasaki RS, Ozdilek BA, Garst AD, Choudhury A, Batey RT. Small molecule regulated sgRNAs enable control of genome editing in E. coli by Cas9. Nat Commun. 2020 Mar 13; 11(1):1394.
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Kiggins C, Skinner A, Resendiz MJE. 7,8-Dihydro-8-oxoguanosine Lesions Inhibit the Theophylline Aptamer or Change Its Selectivity. Chembiochem. 2020 05 04; 21(9):1347-1355.
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Meek P, Lareau S, Fahy B, Austegard E. Medicines for COPD. Am J Respir Crit Care Med. 2019 07 15; 200(2):P3-P5.
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Szefler SJ. Dr Elliot F. Ellis: Initiating personalized asthma management in children. Ann Allergy Asthma Immunol. 2018 07; 121(1):3-6.
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Strand TE, Khiabani HZ, Boico A, Radiloff D, Zhao Y, Hamilton KL, Christians U, Klawitter J, Noveck RJ, Piantadosi CA, Bell C, Irwin D, Schroeder T. The novel combination of theophylline and bambuterol as a potential treatment of hypoxemia in humans. Can J Physiol Pharmacol. 2017 Sep; 95(9):1009-1018.
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Warfield BM, Anderson PC. Molecular simulations and Markov state modeling reveal the structural diversity and dynamics of a theophylline-binding RNA aptamer in its unbound state. PLoS One. 2017; 12(4):e0176229.
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Swift I, Satti A, Kim V, Make BJ, Newell J, Steiner RM, Wilson C, Murphy JR, Silverman EK, Criner GJ. Demographic, physiologic and radiographic characteristics of COPD patients taking chronic systemic corticosteroids. COPD. 2012 Feb; 9(1):29-35.
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