Tacrolimus
"Tacrolimus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
Descriptor ID |
D016559
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MeSH Number(s) |
D02.540.505.810
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Concept/Terms |
Anhydrous Tacrolimus- Anhydrous Tacrolimus
- Tacrolimus, Anhydrous
- Tacrolimus Anhydrous
- Anhydrous, Tacrolimus
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Below are MeSH descriptors whose meaning is more general than "Tacrolimus".
Below are MeSH descriptors whose meaning is more specific than "Tacrolimus".
This graph shows the total number of publications written about "Tacrolimus" by people in this website by year, and whether "Tacrolimus" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 | 1996 | 1 | 1 | 2 | 1997 | 1 | 1 | 2 | 1998 | 1 | 0 | 1 | 1999 | 0 | 2 | 2 | 2001 | 2 | 1 | 3 | 2002 | 2 | 2 | 4 | 2003 | 3 | 4 | 7 | 2004 | 4 | 3 | 7 | 2005 | 7 | 3 | 10 | 2006 | 2 | 0 | 2 | 2007 | 3 | 3 | 6 | 2008 | 2 | 0 | 2 | 2009 | 2 | 2 | 4 | 2010 | 3 | 1 | 4 | 2011 | 3 | 3 | 6 | 2012 | 1 | 1 | 2 | 2013 | 5 | 1 | 6 | 2014 | 3 | 1 | 4 | 2015 | 4 | 0 | 4 | 2016 | 4 | 1 | 5 | 2017 | 5 | 0 | 5 | 2018 | 0 | 1 | 1 | 2019 | 2 | 1 | 3 | 2020 | 2 | 2 | 4 | 2021 | 2 | 5 | 7 | 2022 | 2 | 2 | 4 | 2023 | 0 | 2 | 2 | 2024 | 4 | 0 | 4 |
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Below are the most recent publications written about "Tacrolimus" by people in Profiles.
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Bae EK, Chandran MM, Everitt MD, Benz E, Bock M. LCP-Tacrolimus Extended-Release (Envarsus XR) Use in Adolescent and Young Adult Solid Organ Transplant Recipients. Clin Transplant. 2024 Aug; 38(8):e15417.
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Deininger KM, Anderson HD, Patrinos GP, Mitropoulou C, Aquilante CL. Cost-effectiveness analysis of CYP3A5 genotype-guided tacrolimus dosing in solid organ transplantation using real-world data. Pharmacogenomics J. 2024 May 15; 24(3):14.
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Liu M, Hernandez S, Aquilante CL, Deininger KM, Lindenfeld J, Schlendorf KH, Van Driest SL. Composite CYP3A (CYP3A4 and CYP3A5) phenotypes and influence on tacrolimus dose adjusted concentrations in adult heart transplant recipients. Pharmacogenomics J. 2024 Feb 15; 24(2):4.
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Xiao B, Feturi F, Su AA, Van der Merwe Y, Barnett JM, Jabbari K, Khatter NJ, Li B, Katzel EB, Venkataramanan R, Solari MG, Wagner WR, Steketee MB, Simons DJ, Washington KM. Nerve Wrap for Local Delivery of FK506/Tacrolimus Accelerates Nerve Regeneration. Int J Mol Sci. 2024 Jan 10; 25(2).
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Chu DK, Chu AWL, Rayner DG, Guyatt GH, Yepes-Nu?ez JJ, Gomez-Escobar L, P?rez-Herrera LC, D?az Martinez JP, Brignardello-Petersen R, Sadeghirad B, Wong MM, Ceccacci R, Zhao IX, Basmaji J, MacDonald M, Chu X, Islam N, Gao Y, Izcovich A, Asiniwasis RN, Boguniewicz M, De Benedetto A, Capozza K, Chen L, Ellison K, Frazier WT, Greenhawt M, Huynh J, LeBovidge J, Lio PA, Martin SA, O'Brien M, Ong PY, Silverberg JI, Spergel JM, Smith Begolka W, Wang J, Wheeler KE, Gardner DD, Schneider L. Topical treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials. J Allergy Clin Immunol. 2023 12; 152(6):1493-1519.
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Almond CS, Sleeper LA, Rossano JW, Bock MJ, Pahl E, Auerbach S, Lal A, Hollander SA, Miyamoto SD, Castleberry C, Lee J, Barkoff LM, Gonzales S, Klein G, Daly KP. The teammate trial: Study design and rationale tacrolimus and everolimus against tacrolimus and MMF in pediatric heart transplantation using the major adverse transplant event (MATE) score. Am Heart J. 2023 06; 260:100-112.
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Edwards Mayhew RG, Li T, McCann P, Leslie L, Strong Caldwell A, Palestine AG. Non-biologic, steroid-sparing therapies for non-infectious intermediate, posterior, and panuveitis in adults. Cochrane Database Syst Rev. 2022 10 31; 10:CD014831.
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Berthold EJ, Ma-Lauer Y, Chakraborty A, von Brunn B, Hilgendorff A, Hatz R, Behr J, Hausch F, Staab-Weijnitz CA, von Brunn A. Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models. Front Cell Infect Microbiol. 2022; 12:958634.
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Elgendy TY, Waldner M, Zhang W, Kim DY, Minervini MI, Komatsu C, Kulahci Y, Washington KM, Gorantla VS, Ezzelarab MB, Solari MG, Thomson AW. Tacrolimus before CTLA4Ig and rapamycin promotes vascularized composite allograft survival in MGH miniature swine. Transpl Immunol. 2022 12; 75:101696.
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Feturi FG, Unadkat JV, Zhang W, Hag ME, Wang Y, Komatsu C, Grybowski D, Zhang Z, Erbas V, Sahin H, Mcclaine S, Oksuz S, Plock J, Gorantla VS, Washington KM, Solari MG, Venkataramanan R, Spiess AM. Tacrolimus-Eluting Disk within the Allograft Enables Vascularized Composite Allograft Survival with Site-Specific Immunosuppression without Systemic Toxicity. Pharm Res. 2022 Sep; 39(9):2179-2190.
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