 Xanthine
"Xanthine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed)
| Descriptor ID |
D019820
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| MeSH Number(s) |
D03.132.960.938 D03.633.100.759.758.824.938
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Xanthine".
Below are MeSH descriptors whose meaning is more specific than "Xanthine".
This graph shows the total number of publications written about "Xanthine" by people in this website by year, and whether "Xanthine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Xanthine" by people in Profiles.
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D'Alessandro A, Fu X, Reisz JA, Kanias T, Page GP, Stone M, Kleinman S, Zimring JC, Busch M. Stored RBC metabolism as a function of caffeine levels. Transfusion. 2020 06; 60(6):1197-1211.
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Haines NR, Manoharan N, Olson JL, D'Alessandro A, Reisz JA. Metabolomics Analysis of Human Vitreous in Diabetic Retinopathy and Rhegmatogenous Retinal Detachment. J Proteome Res. 2018 07 06; 17(7):2421-2427.
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O'Loughlin EV, Pang GP, Noltorp R, Koina C, Batey R, Clancy R. Interleukin 2 modulates ion secretion and cell proliferation in cultured human small intestinal enterocytes. Gut. 2001 Nov; 49(5):636-43.
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Levartovsky D, Lagziel A, Sperling O, Liberman U, Yaron M, Hosoya T, Ichida K, Peretz H. XDH gene mutation is the underlying cause of classical xanthinuria: a second report. Kidney Int. 2000 Jun; 57(6):2215-20.
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Ross D, Moldeus P. Thiyl radicals--their generation and further reactions. Adv Exp Med Biol. 1986; 197:329-35.
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Ross D, Cotgreave I, Mold?us P. The interaction of reduced glutathione with active oxygen species generated by xanthine-oxidase-catalyzed metabolism of xanthine. Biochim Biophys Acta. 1985 Sep 06; 841(3):278-82.
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