 Masoprocol
"Masoprocol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.
| Descriptor ID |
D009637
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| MeSH Number(s) |
D02.455.426.559.389.140.450.582 D02.455.426.559.389.657.166.550
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| Concept/Terms |
Masoprocol- Masoprocol
- (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol
- Nordihydroguaiaretic Acid
- Nordihydroguaiaretic Acid, (R*,S*)-Isomer
- Dihydronorguaiaretic Acid
- meso-Nordihydroguaiaretic Acid
- Acid, meso-Nordihydroguaiaretic
- meso Nordihydroguaiaretic Acid
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Below are MeSH descriptors whose meaning is more general than "Masoprocol".
Below are MeSH descriptors whose meaning is more specific than "Masoprocol".
This graph shows the total number of publications written about "Masoprocol" by people in this website by year, and whether "Masoprocol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Masoprocol" by people in Profiles.
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Bashyal B, Li L, Bains T, Debnath A, LaBarbera DV. Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri. PLoS Negl Trop Dis. 2017 Aug; 11(8):e0005832.
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Blecha JE, Anderson MO, Chow JM, Guevarra CC, Pender C, Penaranda C, Zavodovskaya M, Youngren JF, Berkman CE. Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs. Bioorg Med Chem Lett. 2007 Jul 15; 17(14):4026-9.
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Youngren JF, Gable K, Penaranda C, Maddux BA, Zavodovskaya M, Lobo M, Campbell M, Kerner J, Goldfine ID. Nordihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast cancer cells. Breast Cancer Res Treat. 2005 Nov; 94(1):37-46.
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