 Cathepsin L
"Cathepsin L" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously-expressed cysteine protease that plays an enzymatic role in POST-TRANSLATIONAL PROTEIN PROCESSING of proteins within SECRETORY GRANULES.
| Descriptor ID |
D056668
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| MeSH Number(s) |
D08.811.277.656.224.407 D08.811.277.656.262.500.157 D08.811.277.656.300.200.157
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cathepsin L".
Below are MeSH descriptors whose meaning is more specific than "Cathepsin L".
This graph shows the total number of publications written about "Cathepsin L" by people in this website by year, and whether "Cathepsin L" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cathepsin L" by people in Profiles.
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Paschoalin T, Martens AA, Omori ?T, Pereira FV, Juliano L, Travassos LR, Machado-Santelli GM, Cunha RLOR. Antitumor effect of chiral organotelluranes elicited in a murine melanoma model. Bioorg Med Chem. 2019 06 15; 27(12):2537-2545.
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Weiss-Sadan T, Maimoun D, Oelschlagel D, Kaschani F, Misiak D, Gaikwad H, Ben-Nun Y, Merquiol E, Anaki A, Tsvirkun D, Kaiser M, Michl P, Gotsman I, Blum G. Cathepsins Drive Anti-Inflammatory Activity by Regulating Autophagy and Mitochondrial Dynamics in Macrophage Foam Cells. Cell Physiol Biochem. 2019; 53(3):550-572.
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Ben-Mahmoud S, Ramos JE, Shatters RG, Roug? P, Powell CA, Smagghe G, Borovsky D. Cloning and characterization of a basic cysteine-like protease (cathepsin L1) expressed in the gut of larval Diaprepes abbreviatus L. (Coleoptera: Curculionidae). J Insect Physiol. 2015 Jan; 72:1-13.
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Sottnik JL, Lori JC, Rose BJ, Thamm DH. Glycolysis inhibition by 2-deoxy-D-glucose reverts the metastatic phenotype in vitro and in vivo. Clin Exp Metastasis. 2011 Dec; 28(8):865-75.
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Rossi S, Stoppani E, Martinet W, Bonetto A, Costelli P, Giuliani R, Colombo F, Preti A, Marchesini S, Fanzani A. The cytosolic sialidase Neu2 is degraded by autophagy during myoblast atrophy. Biochim Biophys Acta. 2009 Aug; 1790(8):817-28.
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Ebert DH, Wetzel JD, Brumbaugh DE, Chance SR, Stobie LE, Baer GS, Dermody TS. Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3. J Virol. 2001 Apr; 75(7):3197-206.
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Kondoh G, Yomogida K, Dohmae K, Nozawa M, Koga M, Nonomura N, Miki T, Okuyama A, Nishimune Y. Coexpression of multiple Sertoli cell and Leydig cell marker genes in the spontaneous testicular tumor of F344 rat: evidence for phenotypical bifurcation of the interstitial cell tumor. Jpn J Cancer Res. 1997 Sep; 88(9):839-45.
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Edelstein CL, Wieder ED, Yaqoob MM, Gengaro PE, Burke TJ, Nemenoff RA, Schrier RW. The role of cysteine proteases in hypoxia-induced rat renal proximal tubular injury. Proc Natl Acad Sci U S A. 1995 Aug 15; 92(17):7662-6.
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