 Eukaryotic Initiation Factor-1
"Eukaryotic Initiation Factor-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A eukaryotic initiation factor that binds to 40S ribosomal subunits. Although initially considered a "non-essential" factor for eukaryotic transcription initiation, eukaryotic initiation factor-1 is now thought to play an important role in localizing RIBOSOMES at the initiation codon of MRNA.
| Descriptor ID |
D015977
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| MeSH Number(s) |
D12.776.835.725.868.124
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| Concept/Terms |
Eukaryotic Initiation Factor-1- Eukaryotic Initiation Factor-1
- Eukaryotic Initiation Factor 1
- Eukaryotic Peptide Initiation Factor-1
- Eukaryotic Peptide Initiation Factor 1
- Peptide Initiation Factor EIF-1
- Peptide Initiation Factor EIF 1
- EIF-1
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Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-1".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-1".
This graph shows the total number of publications written about "Eukaryotic Initiation Factor-1" by people in this website by year, and whether "Eukaryotic Initiation Factor-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Eukaryotic Initiation Factor-1" by people in Profiles.
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Krishnamoorthy GP, Davidson NR, Leach SD, Zhao Z, Lowe SW, Lee G, Landa I, Nagarajah J, Saqcena M, Singh K, Wendel HG, Dogan S, Tamarapu PP, Blenis J, Ghossein RA, Knauf JA, R?tsch G, Fagin JA. EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC. Cancer Discov. 2019 02; 9(2):264-281.
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Jaafar ZA, Oguro A, Nakamura Y, Kieft JS. Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling. Elife. 2016 12 23; 5.
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Carter AP, Clemons WM, Brodersen DE, Morgan-Warren RJ, Hartsch T, Wimberly BT, Ramakrishnan V. Crystal structure of an initiation factor bound to the 30S ribosomal subunit. Science. 2001 Jan 19; 291(5503):498-501.
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