Class Ia Phosphatidylinositol 3-Kinase
"Class Ia Phosphatidylinositol 3-Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the heterodimerization of a p110 catalytic and a p85, p55, or p50 regulatory subunit. This subclass of enzymes is a downstream target of TYROSINE KINASE RECEPTORS and G PROTEIN-COUPLED RECEPTORS.
Descriptor ID |
D058543
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MeSH Number(s) |
D08.811.913.696.620.500.100.100.100 D08.811.913.696.620.500.200.100.100 D12.776.476.162.100
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Concept/Terms |
Class Ia Phosphatidylinositol 3-Kinase- Class Ia Phosphatidylinositol 3-Kinase
- Class Ia Phosphatidylinositol 3 Kinase
- Phosphatidylinositol 3-Kinase, Class Ia
- Phosphatidylinositol 3 Kinase, Class Ia
- Class Ia Phosphatidylinositol 3-Kinases
- Class Ia Phosphatidylinositol 3 Kinases
Class Ia Phosphatidylinositol 3-Kinase, p110beta Subunit- Class Ia Phosphatidylinositol 3-Kinase, p110beta Subunit
- Class Ia Phosphatidylinositol 3 Kinase, p110beta Subunit
- Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide
- p110beta Subunit, Class Ia Phosphatidylinositol 3-Kinase
- p110beta Subunit, Class Ia Phosphatidylinositol 3 Kinase
Class Ia Phosphatidylinositol 3-Kinase, p110delta Subunit- Class Ia Phosphatidylinositol 3-Kinase, p110delta Subunit
- Class Ia Phosphatidylinositol 3 Kinase, p110delta Subunit
- Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide
- p110delta Subunit, Class Ia Phosphatidylinositol 3-Kinase
- p110delta Subunit, Class Ia Phosphatidylinositol 3 Kinase
Class Ia Phosphatidylinositol 3-Kinase, p85beta Subunit- Class Ia Phosphatidylinositol 3-Kinase, p85beta Subunit
- Class Ia Phosphatidylinositol 3 Kinase, p85beta Subunit
- p85beta Subunit, Class Ia Phosphatidylinositol 3-Kinase
- p85beta Subunit, Class Ia Phosphatidylinositol 3 Kinase
- Phosphoinositide-3-Kinase, Regulatory Subunit 2
- Phosphoinositide 3 Kinase, Regulatory Subunit 2
- Class Ia Phosphatidylinositol 3-kinase, Regulatory, beta Polypeptide
Class Ia Phosphatidylinositol 3-Kinase, p55alpha Subunit- Class Ia Phosphatidylinositol 3-Kinase, p55alpha Subunit
- Class Ia Phosphatidylinositol 3 Kinase, p55alpha Subunit
- p55alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase
- p55alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase
Class Ia Phosphatidylinositol 3-Kinase, p55gamma Subunit- Class Ia Phosphatidylinositol 3-Kinase, p55gamma Subunit
- Class Ia Phosphatidylinositol 3 Kinase, p55gamma Subunit
- p55gamma Subunit, Class Ia Phosphatidylinositol 3-Kinase
- p55gamma Subunit, Class Ia Phosphatidylinositol 3 Kinase
- Phosphoinositide-3-Kinase, Regulatory Subunit 3
- Phosphoinositide 3 Kinase, Regulatory Subunit 3
- Class Ia Phosphatidylinositol 3-kinase, Regulatory, gamma Polypeptide
Class Ia Phosphatidylinositol 3-Kinase, p85alpha Subunit- Class Ia Phosphatidylinositol 3-Kinase, p85alpha Subunit
- Class Ia Phosphatidylinositol 3 Kinase, p85alpha Subunit
- Phosphoinositide-3-Kinase, Regulatory Subunit 1
- Phosphoinositide 3 Kinase, Regulatory Subunit 1
- p85alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase
- p85alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase
- alpha-P85 Subunit, PI-3K
- PI-3K alpha-P85 Subunit
- Class Ia Phosphatidylinositol 3-kinase, Regulatory, alpha Polypeptide
Class Ia Phosphatidylinositol 3-Kinase, p110alpha Subunit- Class Ia Phosphatidylinositol 3-Kinase, p110alpha Subunit
- Class Ia Phosphatidylinositol 3 Kinase, p110alpha Subunit
- Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide
- p110alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase
- p110alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase
Class Ia Phosphatidylinositol 3-Kinase, p50alpha Subunit- Class Ia Phosphatidylinositol 3-Kinase, p50alpha Subunit
- Class Ia Phosphatidylinositol 3 Kinase, p50alpha Subunit
- p50alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase
- p50alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase
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Below are MeSH descriptors whose meaning is more general than "Class Ia Phosphatidylinositol 3-Kinase".
Below are MeSH descriptors whose meaning is more specific than "Class Ia Phosphatidylinositol 3-Kinase".
This graph shows the total number of publications written about "Class Ia Phosphatidylinositol 3-Kinase" by people in this website by year, and whether "Class Ia Phosphatidylinositol 3-Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2012 | 1 | 0 | 1 | 2018 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Class Ia Phosphatidylinositol 3-Kinase" by people in Profiles.
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Greaves SA, Peterson JN, Strauch P, Torres RM, Pelanda R. Active PI3K abrogates central tolerance in high-avidity autoreactive B cells. J Exp Med. 2019 05 06; 216(5):1135-1153.
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Clayton ZS, McCurdy CE. Short-term thermoneutral housing alters glucose metabolism and markers of adipose tissue browning in response to a high-fat diet in lean mice. Am J Physiol Regul Integr Comp Physiol. 2018 10 01; 315(4):R627-R637.
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Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, Anderson SM, Tsichlis PN, Leone G, Wagner KU. Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis. Mol Cell Biol. 2014 Apr; 34(7):1363-77.
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McCurdy CE, Schenk S, Holliday MJ, Philp A, Houck JA, Patsouris D, MacLean PS, Majka SM, Klemm DJ, Friedman JE. Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice. Diabetes. 2012 Oct; 61(10):2495-505.
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