 Polyneuropathies
"Polyneuropathies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.
| Descriptor ID |
D011115
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| MeSH Number(s) |
C10.668.829.800
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| Concept/Terms |
Polyneuropathy, Motor- Polyneuropathy, Motor
- Motor Polyneuropathies
- Motor Polyneuropathy
- Polyneuropathies, Motor
Polyneuropathy, Familial- Polyneuropathy, Familial
- Familial Polyneuropathies
- Familial Polyneuropathy
- Polyneuropathies, Familial
- Polyneuropathy, Inherited
- Inherited Polyneuropathies
- Inherited Polyneuropathy
- Polyneuropathies, Inherited
Polyneuropathy, Acquired- Polyneuropathy, Acquired
- Acquired Polyneuropathies
- Acquired Polyneuropathy
- Polyneuropathies, Acquired
Polyneuropathy, Critical Illness- Polyneuropathy, Critical Illness
- Critical Illness Polyneuropathies
- Critical Illness Polyneuropathy
- Polyneuropathies, Critical Illness
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Below are MeSH descriptors whose meaning is more general than "Polyneuropathies".
Below are MeSH descriptors whose meaning is more specific than "Polyneuropathies".
This graph shows the total number of publications written about "Polyneuropathies" by people in this website by year, and whether "Polyneuropathies" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 2 | 0 | 2 | | 2007 | 3 | 0 | 3 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 | | 2011 | 2 | 0 | 2 | | 2012 | 2 | 1 | 3 | | 2013 | 2 | 1 | 3 | | 2014 | 2 | 1 | 3 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 3 | 0 | 3 | | 2022 | 2 | 0 | 2 | | 2024 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polyneuropathies" by people in Profiles.
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Hussain Y, Malhotra S, Sperry BW, Shu F, Ananthasubramaniam K, Desai U, Egolum U, Fernandez J, Freimer M, Mauricio E, Quan D, Small R, Capocelli K, Roblin S, Bender S, Jay PY, Yureneva E, Zolty R. Impact of patisiran on polyneuropathy of hereditary transthyretin amyloidosis in patients with a V122I or T60A variant: a phase IV multicenter study. Ann Med. 2025 Dec; 57(1):2537347.
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Lee CG, Ciarleglio A, Edelstein SL, Crandall JP, Dabelea D, Goldberg RB, Kahn SE, Knowler WC, Ma MT, White NH, Herman WH. Prevalence of Distal Symmetrical Polyneuropathy by Diabetes Prevention Program Treatment Group, Diabetes Status, Duration of Diabetes, and Cumulative Glycemic Exposure. Diabetes Care. 2024 May 01; 47(5):810-817.
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Forbes E, Smith K, Petluru M, Nystrom J, Fridman V. Adult-onset Krabbe disease presenting as isolated sensorimotor demyelinating polyneuropathy: A case report. J Peripher Nerv Syst. 2022 12; 27(4):320-324.
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Quan D, Obici L, Berk JL, Ando Y, Aldinc E, White MT, Adams D. Impact of baseline polyneuropathy severity on patisiran treatment outcomes in the APOLLO trial. Amyloid. 2023 Mar; 30(1):49-58.
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Stewart SL, Thomas S, Höke E, Simpson D, Singleton JR, Höke A. Vitamin B6 levels do not correlate with severity of neuropathy in chronic idiopathic axonal polyneuropathy. J Peripher Nerv Syst. 2022 03; 27(1):31-37.
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Swingle KL, Hamilton AG, Mitchell MJ. Lipid Nanoparticle-Mediated Delivery of mRNA Therapeutics and Vaccines. Trends Mol Med. 2021 06; 27(6):616-617.
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Barohn RJ, Gajewski B, Pasnoor M, Brown A, Herbelin LL, Kimminau KS, Mudaranthakam DP, Jawdat O, Dimachkie MM, Iyadurai S, Stino A, Kissel J, Pascuzzi R, Brannagan T, Wicklund M, Ahmed A, Walk D, Smith G, Quan D, Heitzman D, Tobon A, Ladha S, Wolfe G, Pulley M, Hayat G, Li Y, Thaisetthawatkul P, Lewis R, Biliciler S, Sharma K, Salajegheh K, Trivedi J, Mallonee W, Burns T, Jacoby M, Bril V, Vu T, Ramchandren S, Bazant M, Austin S, Karam C, Hussain Y, Kutz C, Twydell P, Scelsa S, Kushlaf H, Wymer J, Hehir M, Kolb N, Ralph J, Barboi A, Verma N, Ahmed M, Memon A, Saperstein D, Lou JS, Swenson A, Cash T. Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS): Bayesian Adaptive Comparative Effectiveness Randomized Trial. JAMA Neurol. 2021 01 01; 78(1):68-76.
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Adams D, Polydefkis M, González-Duarte A, Wixner J, Kristen AV, Schmidt HH, Berk JL, Losada López IA, Dispenzieri A, Quan D, Conceição IM, Slama MS, Gillmore JD, Kyriakides T, Ajroud-Driss S, Waddington-Cruz M, Mezei MM, Planté-Bordeneuve V, Attarian S, Mauricio E, Brannagan TH, Ueda M, Aldinc E, Wang JJ, White MT, Vest J, Berber E, Sweetser MT, Coelho T. Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study. Lancet Neurol. 2021 01; 20(1):49-59.
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González-Duarte A, Berk JL, Quan D, Mauermann ML, Schmidt HH, Polydefkis M, Waddington-Cruz M, Ueda M, Conceição IM, Kristen AV, Coelho T, Cauquil CA, Tard C, Merkel M, Aldinc E, Chen J, Sweetser MT, Wang JJ, Adams D. Analysis of autonomic outcomes in APOLLO, a phase III trial of the RNAi therapeutic patisiran in patients with hereditary transthyretin-mediated amyloidosis. J Neurol. 2020 Mar; 267(3):703-712.
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Zakin E, Abrams R, Simpson DM. Diabetic Neuropathy. Semin Neurol. 2019 10; 39(5):560-569.
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