 RNA Recognition Motif
"RNA Recognition Motif" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An approximately 80 amino acid RNA binding motif that consists of four anti-parallel surface beta sheets and two alpha helices arranged in a beta-alpha-beta-beta-alpha-beta configuration. One of the surface beta sheets interacts with two or three specific RNA bases. Interactions between additional sequences and the RNA, as well as within the RNA recognition motif increase the affinity and specificity of the protein-RNA interaction.
| Descriptor ID |
D000071377
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| MeSH Number(s) |
G02.111.570.820.709.275.500.869.500
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| Concept/Terms |
RNA Recognition Motif- RNA Recognition Motif
- RNA Recognition Motifs
- Ribonucleoprotein Domain
- Ribonucleoprotein Domains
- RRM Motif
- RRM Motifs
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Below are MeSH descriptors whose meaning is more general than "RNA Recognition Motif".
Below are MeSH descriptors whose meaning is more specific than "RNA Recognition Motif".
This graph shows the total number of publications written about "RNA Recognition Motif" by people in this website by year, and whether "RNA Recognition Motif" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "RNA Recognition Motif" by people in Profiles.
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Lloyd NR, Wuttke DS. Cyp33 binds AU-rich RNA motifs via an extended interface that competitively disrupts the gene repressive Cyp33-MLL1 interaction in vitro. PLoS One. 2021; 16(2):e0237956.
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Nichols PJ, Bevers S, Henen M, Kieft JS, Vicens Q, V?geli B. Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions. Nat Commun. 2021 02 04; 12(1):793.
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Ripin N, Boudet J, Duszczyk MM, Hinniger A, Faller M, Krepl M, Gadi A, Schneider RJ, ?poner J, Meisner-Kober NC, Allain FH. Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM. Proc Natl Acad Sci U S A. 2019 02 19; 116(8):2935-2944.
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