 Adenosine Deaminase
"Adenosine Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydrolysis of ADENOSINE to INOSINE with the elimination of AMMONIA.
| Descriptor ID |
D000243
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| MeSH Number(s) |
D08.811.277.151.486.075
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| Concept/Terms |
Adenosine Deaminase- Adenosine Deaminase
- Deaminase, Adenosine
- Adenosine Aminohydrolase
- Aminohydrolase, Adenosine
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Below are MeSH descriptors whose meaning is more general than "Adenosine Deaminase".
Below are MeSH descriptors whose meaning is more specific than "Adenosine Deaminase".
This graph shows the total number of publications written about "Adenosine Deaminase" by people in this website by year, and whether "Adenosine Deaminase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 2006 | 2 | 0 | 2 | | 2007 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2021 | 4 | 0 | 4 | | 2022 | 0 | 1 | 1 | | 2023 | 2 | 1 | 3 | | 2024 | 1 | 1 | 2 | | 2025 | 4 | 0 | 4 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Adenosine Deaminase" by people in Profiles.
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Kroft CW, Krall JB, Warchol M, Welty R, Herbert A, Henen MA, Vögeli B. Za and Zß domains of ADAR1 and ZBP1 bind G-quadruplexes with nanomolar affinities, establishing Zß as a G-quadruplex-specific domain. Nucleic Acids Res. 2026 Apr 23; 54(8).
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Yue J, LeSon CE, Rimland CA, Brodeur K, Weng R, Hsu EE, Lam MT, Meyer M, Okada S, Hsu ALD, Alhezam MA, Perron MM, Halyabar O, Dedeoglu F, Nigrovic PA, Shimamura A, Rowe RG, Cooper MA, Vogel TP, Gillispie-Taylor M, Peterson R, Lin C, Nowicki KD, Dollerschell K, Nakano TA, Labrosse R, Cochino AV, Ioan A, Mendonca LO, Barros SF, Kalil J, Perez-Rojas J, Diaz-Kuan A, Sobel ES, Moussa T, Lee SSM, Koh LW, Khan A, Sutnga S, Khubchandani R, Shoman W, El Chazli Y, Pinto B, Kavadichanda C, Abraham RS, Sun X, Zhou Q, Naidu G, Sharma A, Esperanzate C, Kastner DL, Aksentijevich I, Kelly SJ, Hershfield M, Tarrant TK, Lee PY. Diagnostic Implications and Correlates of Plasma Adenosine Deaminase 2 Activity and ADA2 Variants. Arthritis Rheumatol. 2026 Mar; 78(3):734-742.
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Woodcock CC, Maroli G, Kim H, Tai YY, Tang Y, Okawa S, Homsi R, Kim Y, Cho ST, Jiang S, Chauvet C, Wang B, Al Aaraj Y, Lafyatis R, Saggar R, Sembrat J, Wang Q, Li Q, Frump AL, Lahm T, McCubbrey AL, Kudryashova TV, Goncharova EA, Nouraie SM, Bertero T, Yuan K, Pullamsetti SS, Chan SY. Endothelial ADAR1 Deficit Induces the NOCT-IRF7 Axis in Pulmonary Hypertension. Circ Res. 2026 Jan 02; 138(1):e326277.
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Langdon N, Kroft C, Fang Q, Krall J, Rincon M, Vögeli B, Vicens Q, Henen MA. Cromolyn as a novel pharmacophore of the Za domain of the RNA-editing enzyme ADAR1p150. Protein Sci. 2025 Nov; 34(11):e70341.
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Miller CM, Morrison JH, Bankers L, Dran R, Kendrick JM, Briggs E, Ferguson VL, Poeschla EM. ADAR1 haploinsufficiency and sustained picornaviral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy. mBio. 2025 Aug 13; 16(8):e0149225.
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Abe-Ridgway K, Puente MA. Bilateral cataracts in a three-year-old with deficiency of adenosine deaminase 2 (DADA2), hyperferritinemia, and prolonged steroid use. Ophthalmic Genet. 2025 Feb; 46(1):74-78.
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Nichols PJ, Welty R, Krall JB, Henen MA, Vicens Q, Vögeli B. Za Domain of ADAR1 Binds to an A-Form-like Nucleic Acid Duplex with Low Micromolar Affinity. Biochemistry. 2024 03 19; 63(6):777-787.
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Lee PY, Davidson BA, Abraham RS, Alter B, Arostegui JI, Bell K, Belot A, Bergerson JRE, Bernard TJ, Brogan PA, Berkun Y, Deuitch NT, Dimitrova D, Georgin-Lavialle SA, Gattorno M, Grimbacher B, Hashem H, Hershfield MS, Ichord RN, Izawa K, Kanakry JA, Khubchandani RP, Klouwer FCC, Luton EA, Man AW, Meyts I, Van Montfrans JM, Ozen S, Saarela J, Santo GC, Sharma A, Soldatos A, Sparks R, Torgerson TR, Uriarte IL, Youngstein TAB, Zhou Q, Aksentijevich I, Kastner DL, Chambers EP, Ombrello AK. Evaluation and Management of Deficiency of Adenosine Deaminase 2: An International Consensus Statement. JAMA Netw Open. 2023 05 01; 6(5):e2315894.
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Langeberg CJ, Nichols PJ, Henen MA, Vicens Q, Vögeli B. Differential Structural Features of Two Mutant ADAR1p150 Za Domains Associated with Aicardi-Goutières Syndrome. J Mol Biol. 2023 04 15; 435(8):168040.
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Nichols PJ, Krall JB, Henen MA, Vögeli B, Vicens Q. Z-RNA biology: a central role in the innate immune response? RNA. 2023 03; 29(3):273-281.
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