Purinergic P2 Receptor Antagonists
"Purinergic P2 Receptor Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that bind to and block the stimulation of PURINERGIC P2 RECEPTORS.
Descriptor ID |
D058919
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MeSH Number(s) |
D27.505.519.625.725.400.200 D27.505.696.577.725.400.200
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Concept/Terms |
Purinergic P2 Receptor Antagonists- Purinergic P2 Receptor Antagonists
- Purinergic P2 Receptor Blockers
- P2 Purinoceptor Blockers
- Blockers, P2 Purinoceptor
- Purinoceptor Blockers, P2
- P2 Purinoceptor Antagonists
- Antagonists, P2 Purinoceptor
- Purinoceptor Antagonists, P2
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Below are MeSH descriptors whose meaning is more general than "Purinergic P2 Receptor Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Purinergic P2 Receptor Antagonists".
This graph shows the total number of publications written about "Purinergic P2 Receptor Antagonists" by people in this website by year, and whether "Purinergic P2 Receptor Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 | 2005 | 0 | 1 | 1 | 2006 | 0 | 2 | 2 | 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Purinergic P2 Receptor Antagonists" by people in Profiles.
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Dinarello CA. Interleukin-18 and the pathogenesis of inflammatory diseases. Semin Nephrol. 2007 Jan; 27(1):98-114.
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Liao SD, Puro DG. NAD+-induced vasotoxicity in the pericyte-containing microvasculature of the rat retina: effect of diabetes. Invest Ophthalmol Vis Sci. 2006 Nov; 47(11):5032-8.
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Song Z, Vijayaraghavan S, Sladek CD. ATP increases intracellular calcium in supraoptic neurons by activation of both P2X and P2Y purinergic receptors. Am J Physiol Regul Integr Comp Physiol. 2007 Jan; 292(1):R423-31.
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Coddou C, Lorca RA, Acu?a-Castillo C, Grauso M, Rassendren F, Huidobro-Toro JP. Heavy metals modulate the activity of the purinergic P2X4 receptor. Toxicol Appl Pharmacol. 2005 Jan 15; 202(2):121-31.
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Lorca RA, Chac?n M, Barr?a MI, Inestrosa NC, Huidobro-Toro JP. The human prion octarepeat fragment prevents and reverses the inhibitory action of copper in the P2X4 receptor without modifying the zinc action. J Neurochem. 2003 May; 85(3):709-16.
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Kapoor JR, Sladek CD. Purinergic and adrenergic agonists synergize in stimulating vasopressin and oxytocin release. J Neurosci. 2000 Dec 01; 20(23):8868-75.
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Nandanan E, Camaioni E, Jang SY, Kim YC, Cristalli G, Herdewijn P, Secrist JA, Tiwari KN, Mohanram A, Harden TK, Boyer JL, Jacobson KA. Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists. J Med Chem. 1999 May 06; 42(9):1625-38.
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Jacobson KA, Kim YC, Wildman SS, Mohanram A, Harden TK, Boyer JL, King BF, Burnstock G. A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors. J Med Chem. 1998 Jun 18; 41(13):2201-6.
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Boyer JL, Mohanram A, Camaioni E, Jacobson KA, Harden TK. Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate. Br J Pharmacol. 1998 May; 124(1):1-3.
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Camaioni E, Boyer JL, Mohanram A, Harden TK, Jacobson KA. Deoxyadenosine bisphosphate derivatives as potent antagonists at P2Y1 receptors. J Med Chem. 1998 Jan 15; 41(2):183-90.
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