AAA Domain
"AAA Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase subdomain with an alpha-beta-alpha conformation, and a less-conserved C-terminal subdomain with an all alpha conformation. The N-terminal subdomain includes Walker A and Walker B motifs which function in ATP binding and hydrolysis.
Descriptor ID |
D000074182
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MeSH Number(s) |
G02.111.570.820.709.275.500.913
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Concept/Terms |
AAA Domain- AAA Domain
- AAA+ Modules
- AAA+ Module
- Module, AAA+
- Modules, AAA+
- AAA+ Domain
- AAA+ Domains
- Domain, AAA+
- Domains, AAA+
- AAA Modules
- AAA Module
- Module, AAA
- Modules, AAA
- AAA Domains
- Domain, AAA
- Domains, AAA
Walker Motifs- Walker Motifs
- Motifs, Walker
- Walker Motif
- Motif, Walker
- P-Loop
- P Loop
- P-Loops
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Below are MeSH descriptors whose meaning is more general than "AAA Domain".
Below are MeSH descriptors whose meaning is more specific than "AAA Domain".
This graph shows the total number of publications written about "AAA Domain" by people in this website by year, and whether "AAA Domain" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2019 | 1 | 0 | 1 | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "AAA Domain" by people in Profiles.
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Pegram L, Riccardi D, Ahn N. Activation Loop Plasticity and Active Site Coupling in the MAP Kinase, ERK2. J Mol Biol. 2023 12 01; 435(23):168309.
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delToro D, Ortiz D, Ordyan M, Pajak J, Sippy J, Catala A, Oh CS, Vu A, Arya G, Smith DE, Catalano CE, Feiss M. Functional Dissection of a Viral DNA?Packaging Machine's Walker B?Motif. J Mol Biol. 2019 11 08; 431(22):4455-4474.
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