 Endoplasmic Reticulum-Associated Degradation
"Endoplasmic Reticulum-Associated Degradation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.
| Descriptor ID |
D060746
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| MeSH Number(s) |
G02.111.660.871.790.600.962.500 G02.111.691.600.850.500 G03.734.871.790.600.850.500 G05.308.670.600.850.500
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| Concept/Terms |
Endoplasmic Reticulum-Associated Degradation- Endoplasmic Reticulum-Associated Degradation
- Degradation, Endoplasmic Reticulum-Associated
- Endoplasmic Reticulum Associated Degradation
- Reticulum-Associated Degradation, Endoplasmic
- ERAD Pathway
- ERAD Pathways
- Pathway, ERAD
- Pathways, ERAD
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Below are MeSH descriptors whose meaning is more general than "Endoplasmic Reticulum-Associated Degradation".
Below are MeSH descriptors whose meaning is more specific than "Endoplasmic Reticulum-Associated Degradation".
This graph shows the total number of publications written about "Endoplasmic Reticulum-Associated Degradation" by people in this website by year, and whether "Endoplasmic Reticulum-Associated Degradation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Endoplasmic Reticulum-Associated Degradation" by people in Profiles.
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Pioppini C, Bhardwaj R, Schönauer R, Halbritter J, Hassan F, Eckardt KU, Fedeles SV, Yilmaz DE, Krappitz M. Valosin-containing protein in ciliary morphology: a novel target in ADPKD. Am J Physiol Renal Physiol. 2025 Aug 01; 329(2):F300-F310.
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Faulkner RA, Nguyen AD, Jo Y, DeBose-Boyd RA. Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells. J Lipid Res. 2013 Apr; 54(4):1011-22.
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Guerra DD, Callis J. Ubiquitin on the move: the ubiquitin modification system plays diverse roles in the regulation of endoplasmic reticulum- and plasma membrane-localized proteins. Plant Physiol. 2012 Sep; 160(1):56-64.
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