Twist-Related Protein 1
"Twist-Related Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic helix-loop-helix transcription factor that was originally identified in DROSOPHILA as essential for proper gastrulation and MESODERM formation. It plays an important role in EMBRYONIC DEVELOPMENT and CELL DIFFERENTIATION of MUSCLE CELLS, and is found in a wide variety of organisms.
Descriptor ID |
D051879
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MeSH Number(s) |
D12.776.260.103.906.250 D12.776.930.125.906.250
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Concept/Terms |
Twist-Related Protein 1- Twist-Related Protein 1
- Twist Related Protein 1
- Twist Transcription Factor
- Transcription Factor, Twist
- Twist Protein
- TWIST1 Protein
- Twist Family Bhlh Transcription Factor 1
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Below are MeSH descriptors whose meaning is more general than "Twist-Related Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Twist-Related Protein 1".
This graph shows the total number of publications written about "Twist-Related Protein 1" by people in this website by year, and whether "Twist-Related Protein 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 | 2009 | 2 | 0 | 2 | 2011 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2015 | 1 | 1 | 2 | 2018 | 1 | 1 | 2 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Twist-Related Protein 1" by people in Profiles.
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Hartsough EJ, Weiss MB, Heilman SA, Purwin TJ, Kugel CH, Rosenbaum SR, Erkes DA, Tiago M, HooKim K, Chervoneva I, Aplin AE. CADM1 is a TWIST1-regulated suppressor of invasion and survival. Cell Death Dis. 2019 03 25; 10(4):281.
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Kahn SA, Wang X, Nitta RT, Gholamin S, Theruvath J, Hutter G, Azad TD, Wadi L, Bolin S, Ramaswamy V, Esparza R, Liu KW, Edwards M, Swartling FJ, Sahoo D, Li G, Wechsler-Reya RJ, Reimand J, Cho YJ, Taylor MD, Weissman IL, Mitra SS, Cheshier SH. Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma. Nat Commun. 2018 10 08; 9(1):4121.
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Al-Hattab DS, Safi HA, Nagalingam RS, Bagchi RA, Stecy MT, Czubryt MP. Scleraxis regulates Twist1 and Snai1 expression in the epithelial-to-mesenchymal transition. Am J Physiol Heart Circ Physiol. 2018 09 01; 315(3):H658-H668.
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Kwapiszewska G, Crnkovic S, Stenmark KR. A Twist on Pulmonary Vascular Remodeling: Endothelial to Mesenchymal Transition? Am J Respir Cell Mol Biol. 2018 02; 58(2):140-141.
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Avasarala S, Van Scoyk M, Karuppusamy Rathinam MK, Zerayesus S, Zhao X, Zhang W, Pergande MR, Borgia JA, DeGregori J, Port JD, Winn RA, Bikkavilli RK. PRMT1 Is a Novel Regulator of Epithelial-Mesenchymal-Transition in Non-small Cell Lung Cancer. J Biol Chem. 2015 May 22; 290(21):13479-89.
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Drasin DJ, Guarnieri AL, Neelakantan D, Kim J, Cabrera JH, Wang CA, Zaberezhnyy V, Gasparini P, Cascione L, Huebner K, Tan AC, Ford HL. TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation. Cancer Res. 2015 May 01; 75(9):1908-21.
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Firulli BA, Fuchs RK, Vincentz JW, Clouthier DE, Firulli AB. Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis. Development. 2014 Aug; 141(15):3050-61.
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Shi J, Severson C, Yang J, Wedlich D, Klymkowsky MW. Snail2 controls mesodermal BMP/Wnt induction of neural crest. Development. 2011 Aug; 138(15):3135-45.
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James PA, Culling B, Mullan G, Jenkins M, Elakis G, Turner AM, Mowat DM, Wilson M, Anderson P, Savarirayan R, Cliffe ST, Caramins M, Buckley MF, Tucker K, Roscioli T. Breast cancer risk is not increased in individuals with TWIST1 mutation confirmed Saethre-Chotzen syndrome: an Australian multicenter study. Genes Chromosomes Cancer. 2009 Jul; 48(7):533-8.
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Zhang C, Klymkowsky MW. Unexpected functional redundancy between Twist and Slug (Snail2) and their feedback regulation of NF-kappaB via Nodal and Cerberus. Dev Biol. 2009 Jul 15; 331(2):340-9.
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