 SELEX Aptamer Technique
"SELEX Aptamer Technique" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A method of generating a large library of randomized nucleotides and selecting NUCLEOTIDE APTAMERS by iterative rounds of in vitro selection. A modified procedure substitutes AMINO ACIDS in place of NUCLEOTIDES to make PEPTIDE APTAMERS.
| Descriptor ID |
D052156
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| MeSH Number(s) |
E05.197.312.500 J01.897.836.249.249.500
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| Concept/Terms |
SELEX Aptamer Technique- SELEX Aptamer Technique
- Aptamer Technique, SELEX
- Aptamer Techniques, SELEX
- SELEX Aptamer Techniques
- Technique, SELEX Aptamer
- Techniques, SELEX Aptamer
- Systematic Evolution of Ligands by Exponential Enrichment
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Below are MeSH descriptors whose meaning is more general than "SELEX Aptamer Technique".
Below are MeSH descriptors whose meaning is more specific than "SELEX Aptamer Technique".
This graph shows the total number of publications written about "SELEX Aptamer Technique" by people in this website by year, and whether "SELEX Aptamer Technique" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 3 | 0 | 3 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "SELEX Aptamer Technique" by people in Profiles.
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Lloyd NR, Wuttke DS. Cyp33 binds AU-rich RNA motifs via an extended interface that competitively disrupts the gene repressive Cyp33-MLL1 interaction in vitro. PLoS One. 2021; 16(2):e0237956.
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Janas T, Sapon K, Stowell MHB, Janas T. Selection of Membrane RNA Aptamers to Amyloid Beta Peptide: Implications for Exosome-Based Antioxidant Strategies. Int J Mol Sci. 2019 Jan 13; 20(2).
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Sedlyarova N, Rescheneder P, Mag?n A, Popitsch N, Rziha N, Bilusic I, Epshtein V, Zimmermann B, Lybecker M, Sedlyarov V, Schroeder R, Nudler E. Natural RNA Polymerase Aptamers Regulate Transcription in E. coli. Mol Cell. 2017 Jul 06; 67(1):30-43.e6.
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Drolet DW, Green LS, Gold L, Janjic N. Fit for the Eye: Aptamers in Ocular Disorders. Nucleic Acid Ther. 2016 06; 26(3):127-46.
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Gold L. SELEX: How It Happened and Where It will Go. J Mol Evol. 2015 Dec; 81(5-6):140-3.
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Walters RD, McSwiggen DT, Goodrich JA, Kugel JF. Selection and characterization of a DNA aptamer that can discriminate between cJun/cJun and cJun/cFos. PLoS One. 2014; 9(6):e101015.
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Ochsner UA, Green LS, Gold L, Janjic N. Systematic selection of modified aptamer pairs for diagnostic sandwich assays. Biotechniques. 2014; 56(3):125-8, 130, 132-3.
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Gupta S, Hirota M, Waugh SM, Murakami I, Suzuki T, Muraguchi M, Shibamori M, Ishikawa Y, Jarvis TC, Carter JD, Zhang C, Gawande B, Vrkljan M, Janjic N, Schneider DJ. Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor. J Biol Chem. 2014 Mar 21; 289(12):8706-19.
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Davies DR, Gelinas AD, Zhang C, Rohloff JC, Carter JD, O'Connell D, Waugh SM, Wolk SK, Mayfield WS, Burgin AB, Edwards TE, Stewart LJ, Gold L, Janjic N, Jarvis TC. Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets. Proc Natl Acad Sci U S A. 2012 Dec 04; 109(49):19971-6.
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Brody E, Gold L, Mehan M, Ostroff R, Rohloff J, Walker J, Zichi D. Life's simple measures: unlocking the proteome. J Mol Biol. 2012 Oct 05; 422(5):595-606.
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