Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology.
Meloche J, Courchesne A, Barrier M, Carter S, Bisserier M, Paulin R, Lauzon-Joset JF, Breuils-Bonnet S, Tremblay ?, Biardel S, Racine C, Courture C, Bonnet P, Majka SM, Deshaies Y, Picard F, Provencher S, Bonnet S. Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology. J Am Heart Assoc. 2013 Jan 16; 2(1):e005157.
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Adult
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Aged
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Animals
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Apoptosis
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Arterial Pressure
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Bone Morphogenetic Protein Receptors, Type II
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Case-Control Studies
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Cell Proliferation
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Cells, Cultured
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Disease Models, Animal
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Familial Primary Pulmonary Hypertension
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Female
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Glycation End Products, Advanced
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Humans
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Hypertension, Pulmonary
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Hypertrophy, Right Ventricular
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Hypoxia
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Indoles
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Male
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Middle Aged
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Monocrotaline
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Muscle, Smooth, Vascular
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Myocytes, Smooth Muscle
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PPAR gamma
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Pulmonary Artery
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Pyrroles
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Rats
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Rats, Sprague-Dawley
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Receptor for Advanced Glycation End Products
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Receptors, Immunologic
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RNA Interference
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S100 Proteins
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Signal Transduction
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STAT3 Transcription Factor
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Transfection
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Up-Regulation