TWEAK Receptor
"TWEAK Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor for TWEAK cytokine that is highly expressed by cells in the heart, placenta, and kidney. It plays a role in ANGIOGENESIS and the proliferation of endothelial cells; it may also modulate cellular adhesion to the extracellular matrix.
Descriptor ID |
D000074050
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MeSH Number(s) |
D12.776.543.750.705.852.760.974
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Concept/Terms |
TWEAK Receptor- TWEAK Receptor
- Receptor, TWEAK
- Fn14 TWEAK Receptor
- Receptor, Fn14 TWEAK
- TWEAK Receptor, Fn14
- TWEAK Receptor Fn14
- Fn14, TWEAK Receptor
- Receptor Fn14, TWEAK
- Tumor Necrosis Factor-like Weak Inducer of Apoptosis Receptor
- Tumor Necrosis Factor like Weak Inducer of Apoptosis Receptor
- CD266 Antigen
- Antigen, CD266
- Tumor Necrosis Factor Receptor Superfamily, Member 12A
- TNF Receptor Superfamily Member 12A
- TWEAKR
- Fn14 Receptor
- Receptor, Fn14
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Below are MeSH descriptors whose meaning is more general than "TWEAK Receptor".
Below are MeSH descriptors whose meaning is more specific than "TWEAK Receptor".
This graph shows the total number of publications written about "TWEAK Receptor" by people in this website by year, and whether "TWEAK Receptor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2011 | 0 | 1 | 1 | 2017 | 1 | 0 | 1 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "TWEAK Receptor" by people in Profiles.
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Holmberg R, Robinson M, Gilbert SF, Lujano-Olazaba O, Waters JA, Kogan E, Velasquez CLR, Stevenson D, Cruz LS, Alexander LJ, Lara J, Mu EM, Camillo JR, Bitler BG, Huxford T, House CD. TWEAK-Fn14-RelB Signaling Cascade Promotes Stem Cell-like Features that Contribute to Post-Chemotherapy Ovarian Cancer Relapse. Mol Cancer Res. 2023 02 01; 21(2):170-186.
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Lam ET, Eckhardt SG, Messersmith W, Jimeno A, O'Bryant CL, Ramanathan RK, Weiss GJ, Chadha M, Oey A, Ding HT, Culp PA, Keller SF, Zhao VY, Tsao LC, Singhal A, Holen KD, Von Hoff D. Phase I Study of Enavatuzumab, a First-in-Class Humanized Monoclonal Antibody Targeting the TWEAK Receptor, in Patients with Advanced Solid Tumors. Mol Cancer Ther. 2018 01; 17(1):215-221.
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Finlin BS, Varma V, Nolen GT, Dub? J, Starnes CP, Rasouli N, Kern PA, Peterson CA. DHA reduces the atrophy-associated Fn14 protein in differentiated myotubes during coculture with macrophages. J Nutr Biochem. 2012 Aug; 23(8):885-91.
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Iocca HA, Plant SR, Wang Y, Runkel L, O'Connor BP, Lundsmith ET, Hahm K, van Deventer HW, Burkly LC, Ting JP. TNF superfamily member TWEAK exacerbates inflammation and demyelination in the cuprizone-induced model. J Neuroimmunol. 2008 Feb; 194(1-2):97-106.
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