 Polymorphism, Single-Stranded Conformational
"Polymorphism, Single-Stranded Conformational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
| Descriptor ID |
D018807
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| MeSH Number(s) |
G05.365.795.600
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| Concept/Terms |
Polymorphism, Single-Stranded Conformational- Polymorphism, Single-Stranded Conformational
- Polymorphism, Single Stranded Conformational
- SSCP
- Single-Stranded Conformational Polymorphism
- Conformational Polymorphism, Single-Stranded
- Conformational Polymorphisms, Single-Stranded
- Polymorphisms, Single-Stranded Conformational
- Single Stranded Conformational Polymorphism
- Single-Stranded Conformational Polymorphisms
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Below are MeSH descriptors whose meaning is more general than "Polymorphism, Single-Stranded Conformational".
Below are MeSH descriptors whose meaning is more specific than "Polymorphism, Single-Stranded Conformational".
This graph shows the total number of publications written about "Polymorphism, Single-Stranded Conformational" by people in this website by year, and whether "Polymorphism, Single-Stranded Conformational" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 | | 1996 | 0 | 4 | 4 | | 1997 | 0 | 3 | 3 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 3 | 3 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 2 | 3 | | 2004 | 0 | 2 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polymorphism, Single-Stranded Conformational" by people in Profiles.
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Kusz-Zamelczyk K, Sajek M, Spik A, Glazar R, Jedrzejczak P, Latos-Bielenska A, Kotecki M, Pawelczyk L, Jaruzelska J. Mutations of NANOS1, a human homologue of the Drosophila morphogen, are associated with a lack of germ cells in testes or severe oligo-astheno-teratozoospermia. J Med Genet. 2013 Mar; 50(3):187-93.
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Yang LX, Razzaghi H, Hokanson JE, Kamboh MI. Identification and characterization of a novel 5 bp deletion in a putative insulin response element in the lipoprotein lipase gene. Biochim Biophys Acta. 2009 Nov; 1791(11):1057-65.
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Shao C, Xiong S, Li GM, Gu L, Mao G, Markesbery WR, Lovell MA. Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer's disease brain. Free Radic Biol Med. 2008 Sep 15; 45(6):813-9.
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Pine SR, Guo Q, Yin C, Jayabose S, Druschel CM, Sandoval C. Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome. Blood. 2007 Sep 15; 110(6):2128-31.
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Roth MJ, Hu N, Johnson LL, Quon-Hang W, Ahnen DJ, Iwamoto M, Dawsey SM, Taylor PR, Huppi K. beta-Catenin splice variants and downstream targets as markers for neoplastic progression of esophageal cancer. Genes Chromosomes Cancer. 2005 Dec; 44(4):423-8.
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Chong TW, Smith RL, Hughes MG, Camden J, Rudy CK, Evans HL, Sawyer RG, Pruett TL. Primary human hepatocytes in spheroid formation to study hepatitis C infection. J Surg Res. 2006 Jan; 130(1):52-7.
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Huang JL, Gao PS, Mathias RA, Yao TC, Chen LC, Kuo ML, Hsu SC, Plunkett B, Togias A, Barnes KC, Stellato C, Beaty TH, Huang SK. Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability. Hum Mol Genet. 2004 Nov 01; 13(21):2691-7.
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Oiso N, Riddle SR, Serikawa T, Kuramoto T, Spritz RA. The rat Ruby ( R) locus is Rab38: identical mutations in Fawn-hooded and Tester-Moriyama rats derived from an ancestral Long Evans rat sub-strain. Mamm Genome. 2004 Apr; 15(4):307-14.
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Wait SD, Vortmeyer AO, Lonser RR, Chang DT, Finn MA, Bhowmick DA, Pack SD, Oldfield EH, Zhuang Z. Somatic mutations in VHL germline deletion kindred correlate with mild phenotype. Ann Neurol. 2004 Feb; 55(2):236-40.
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Gault J, Hopkins J, Berger R, Drebing C, Logel J, Walton C, Short M, Vianzon R, Olincy A, Ross RG, Adler LE, Freedman R, Leonard S. Comparison of polymorphisms in the alpha7 nicotinic receptor gene and its partial duplication in schizophrenic and control subjects. Am J Med Genet B Neuropsychiatr Genet. 2003 Nov 15; 123B(1):39-49.
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