 Thrombotic Microangiopathies
"Thrombotic Microangiopathies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Diseases that result in THROMBOSIS in MICROVASCULATURE. The two most prominent diseases are PURPURA, THROMBOTIC THROMBOCYTOPENIC; and HEMOLYTIC-UREMIC SYNDROME. Multiple etiological factors include VASCULAR ENDOTHELIAL CELL damage due to SHIGA TOXIN; FACTOR H deficiency; and aberrant VON WILLEBRAND FACTOR formation.
| Descriptor ID |
D057049
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| MeSH Number(s) |
C15.378.140.855.925
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thrombotic Microangiopathies".
Below are MeSH descriptors whose meaning is more specific than "Thrombotic Microangiopathies".
This graph shows the total number of publications written about "Thrombotic Microangiopathies" by people in this website by year, and whether "Thrombotic Microangiopathies" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thrombotic Microangiopathies" by people in Profiles.
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Shah H, Chen H, Pan XZ, Metjian A, Brodsky RA, Braunstein EM, Chaturvedi S. C5 inhibition allows continued antineoplastic therapy in cancer- and chemotherapy-associated thrombotic microangiopathy. Blood Adv. 2022 12 13; 6(23):6071-6074.
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Petr V, Csuka D, Hruba P, Szil?gyi ?, Kollar M, Slavcev A, Proh?szka Z, Viklicky O. MCPggaac haplotype is associated with poor graft survival in kidney transplant recipients with de novo thrombotic microangiopathy. Front Immunol. 2022; 13:985766.
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Ariceta G, Dixon BP, Kim SH, Kapur G, Mauch T, Ortiz S, Vallee M, Denker AE, Kang HG, Greenbaum LA. The long-acting C5 inhibitor, ravulizumab, is effective and safe in pediatric patients with atypical hemolytic uremic syndrome na?ve to complement inhibitor treatment. Kidney Int. 2021 07; 100(1):225-237.
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Thurman JM. A Patient with Hemolytic Uremic Syndrome and Kidney Failure. Clin J Am Soc Nephrol. 2018 06 07; 13(6):933-936.
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Thurman JM, Frazer-Abel A, Holers VM. The Evolving Landscape for Complement Therapeutics in Rheumatic and Autoimmune Diseases. Arthritis Rheumatol. 2017 11; 69(11):2102-2113.
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Bendapudi PK, Hurwitz S, Fry A, Marques MB, Waldo SW, Li A, Sun L, Upadhyay V, Hamdan A, Brunner AM, Gansner JM, Viswanathan S, Kaufman RM, Uhl L, Stowell CP, Dzik WH, Makar RS. Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort study. Lancet Haematol. 2017 Apr; 4(4):e157-e164.
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Hunt R, Yalamanoglu A, Tumlin J, Schiller T, Baek JH, Wu A, Fogo AB, Yang H, Wong E, Miller P, Buehler PW, Kimchi-Sarfaty C. A mechanistic investigation of thrombotic microangiopathy associated with IV abuse of Opana ER. Blood. 2017 02 16; 129(7):896-905.
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Metjian A, Tanhehco YC, Aqui N, Bhoj VG, Jamensky L, Marques MB, Onwuemene O, Pham HP, Arepally GM. The thrombotic microangiopathy Registry of North America: A United States multi-institutional TMA network. J Clin Apher. 2016 Oct; 31(5):448-53.
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Jodele S, Fukuda T, Mizuno K, Vinks AA, Laskin BL, Goebel J, Dixon BP, Chima RS, Hirsch R, Teusink A, Lazear D, Lane A, Myers KC, Dandoy CE, Davies SM. Variable Eculizumab Clearance Requires Pharmacodynamic?Monitoring to Optimize Therapy?for?Thrombotic Microangiopathy after Hematopoietic?Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016 Feb; 22(2):307-315.
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Johnson RJ, Nangaku M. Endothelial Dysfunction: The Secret Agent Driving Kidney Disease. J Am Soc Nephrol. 2016 Jan; 27(1):3-5.
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