Myelinolysis, Central Pontine
"Myelinolysis, Central Pontine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
Descriptor ID |
D017590
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MeSH Number(s) |
C10.228.140.163.560 C10.314.500 C18.452.132.560
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Concept/Terms |
Myelinolysis, Central Pontine- Myelinolysis, Central Pontine
- Pontine Myelinolysis, Central
- Myelinoclasis, Central Pontine
- Central Pontine Myelinoclasis
- Central Pontine Myelinolysis
Extrapontine Myelinolysis- Extrapontine Myelinolysis
- Extrapontine Myelinolyses
- Myelinolyses, Extrapontine
- Myelinolysis, Extrapontine
- Extrapontine Myelinoclasis
- Extrapontine Myelinoclases
- Myelinoclases, Extrapontine
- Myelinoclasis, Extrapontine
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Below are MeSH descriptors whose meaning is more general than "Myelinolysis, Central Pontine".
Below are MeSH descriptors whose meaning is more specific than "Myelinolysis, Central Pontine".
This graph shows the total number of publications written about "Myelinolysis, Central Pontine" by people in this website by year, and whether "Myelinolysis, Central Pontine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 | 2000 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myelinolysis, Central Pontine" by people in Profiles.
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Barhaghi K, Molchanova-Cook O, Rosenburg M, Deal B, Palacios E, Nguyen J, Hanemann C. Osmotic Demyelination Syndrome Revisited: Review With Neuroimaging. J La State Med Soc. 2017 Jul-Aug; 169(4):89-93.
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Hurley RA, Filley CM, Taber KH. Central pontine myelinolysis: a metabolic disorder of myelin. J Neuropsychiatry Clin Neurosci. 2011; 23(4):369-74.
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Kleinschmidt-DeMasters BK, Filley CM, Rojiani AM. Overlapping features of extrapontine myelinolysis and acquired chronic (non-Wilsonian) hepatocerebral degeneration. Acta Neuropathol. 2006 Nov; 112(5):605-16.
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Kleinschmidt-Demasters BK, Rojiani AM, Filley CM. Central and extrapontine myelinolysis: then...and now. J Neuropathol Exp Neurol. 2006 Jan; 65(1):1-11.
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Bridgeford D, Arciniegas DB, Batkis M, Sandberg E, Beresford TP. Methylphenidate treatment of neuropsychiatric symptoms of central and extrapontine myelinolysis. J Stud Alcohol. 2000 Sep; 61(5):657-60.
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Kleinschmidt-DeMasters BK, Anderson CA, Rubinstein D. Asymptomatic pontine lesions found by magnetic resonance imaging: are they central pontine myelinolysis? J Neurol Sci. 1997 Jul; 149(1):27-35.
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