 Osteoclasts
"Osteoclasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.
| Descriptor ID |
D010010
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| MeSH Number(s) |
A11.329.372.700 A11.627.482.700
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| Concept/Terms |
Odontoclasts- Odontoclasts
- Cementoclast
- Odontoclast
- Cementoclasts
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Below are MeSH descriptors whose meaning is more general than "Osteoclasts".
Below are MeSH descriptors whose meaning is more specific than "Osteoclasts".
This graph shows the total number of publications written about "Osteoclasts" by people in this website by year, and whether "Osteoclasts" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2004 | 0 | 2 | 2 | | 2005 | 2 | 1 | 3 | | 2006 | 2 | 1 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 1 | 2 | 3 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 2 | 3 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 2 | 3 | | 2014 | 0 | 2 | 2 | | 2015 | 1 | 1 | 2 | | 2017 | 1 | 1 | 2 | | 2018 | 2 | 0 | 2 | | 2019 | 3 | 3 | 6 | | 2020 | 0 | 2 | 2 | | 2021 | 1 | 1 | 2 | | 2022 | 1 | 1 | 2 | | 2023 | 1 | 2 | 3 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Osteoclasts" by people in Profiles.
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Rizkalla CN, Tretiakova M, Suarez CJ, Williamson SR, Al-Obaidy KI, Acosta AM, Idrees MT, Chan E, Potterveld S, Sangoi AR. Urothelial carcinoma with osteoclast-like giant cells: An expanded immunohistochemical and molecular profile. Am J Clin Pathol. 2025 Aug 26; 164(2):257-264.
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Mullin BH, Zhu K, Brown SJ, Mullin S, Dudbridge F, Pavlos NJ, Richards JB, Grundberg E, Bell JT, Zeggini E, Walsh JP, Xu J, Wilson SG. Leveraging osteoclast genetic regulatory data to identify genes with a role in osteoarthritis. Genetics. 2023 10 04; 225(2).
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Rabjohns EM, Rampersad RR, Ghosh A, Hurst K, Eudy AM, Brozowski JM, Lee HH, Ren Y, Mirando A, Gladman J, Bowser JL, Berg K, Wani S, Ralston SH, Hilton MJ, Tarrant TK. Aged G Protein-Coupled Receptor Kinase 3 (Grk3)-Deficient Mice Exhibit Enhanced Osteoclastogenesis and Develop Bone Lesions Analogous to Human Paget's Disease of Bone. Cells. 2023 03 23; 12(7).
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Tan Q, Møller AMJ, Qiu C, Madsen JS, Shen H, Bechmann T, Delaisse JM, Kristensen BW, Deng HW, Karasik D, Søe K. A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome. Clin Epigenetics. 2023 03 13; 15(1):42.
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Khrystoforova I, Shochat-Carvalho C, Harari R, Henke K, Woronowicz K, Harris MP, Karasik D. Zebrafish mutants reveal unexpected role of Lrp5 in osteoclast regulation. Front Endocrinol (Lausanne). 2022; 13:985304.
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Payne KA, Shaw NM, Erickson CB, Yarger P, Yu Y, Baldini T, Kleck CJ, Patel VV, Burger EL. Blockade of Osteoclast-Mediated Bone Resorption With a RANKL-Inhibitor Enhances Bone Formation in a Rat Spinal Fusion Model. Spine (Phila Pa 1976). 2022 Aug 15; 47(16):1165-1171.
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Pin F, Prideaux M, Huot JR, Essex AL, Plotkin LI, Bonetto A, Bonewald LF. Non-bone metastatic cancers promote osteocyte-induced bone destruction. Cancer Lett. 2021 11 01; 520:80-90.
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Diboun I, Wani S, Ralston SH, Albagha OM. Epigenetic analysis of Paget's disease of bone identifies differentially methylated loci that predict disease status. Elife. 2021 04 30; 10.
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Coulombe JC, Senwar B, Ferguson VL. Spaceflight-Induced Bone Tissue Changes that Affect Bone Quality and Increase Fracture Risk. Curr Osteoporos Rep. 2020 02; 18(1):1-12.
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Elsayed R, Kurago Z, Cutler CW, Arce RM, Gerber J, Celis E, Sultan H, Elashiry M, Meghil M, Sun C, Auersvald CM, Awad ME, Zeitoun R, Elsayed R, Eldin M Elshikh M, Isales C, Elsalanty ME. Role of dendritic cell-mediated immune response in oral homeostasis: A new mechanism of osteonecrosis of the jaw. FASEB J. 2020 02; 34(2):2595-2608.
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