Large-Conductance Calcium-Activated Potassium Channels
"Large-Conductance Calcium-Activated Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.
Descriptor ID |
D051036
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MeSH Number(s) |
D12.776.157.530.400.600.150.500 D12.776.543.550.450.750.150.500 D12.776.543.585.400.750.150.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Large-Conductance Calcium-Activated Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Large-Conductance Calcium-Activated Potassium Channels".
This graph shows the total number of publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in this website by year, and whether "Large-Conductance Calcium-Activated Potassium Channels" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 | 2005 | 1 | 0 | 1 | 2009 | 1 | 0 | 1 | 2011 | 1 | 0 | 1 | 2012 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2014 | 1 | 0 | 1 | 2016 | 1 | 0 | 1 | 2017 | 0 | 1 | 1 | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in Profiles.
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Lorca RA, Wakle-Prabagaran M, Freeman WE, Pillai MK, England SK. The large-conductance voltage- and Ca2+ -activated K+ channel and its ?1-subunit modulate mouse uterine artery function during pregnancy. J Physiol. 2018 03 15; 596(6):1019-1033.
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Sharma V, Nair SV, Jaitley P, Nakade UP, Sharma A, Choudhury S, Garg SK. ATP-sensitive and maxi potassium channels regulate BRL 37344-induced tocolysis in buffaloes-an in?vitro study. Theriogenology. 2018 Feb; 107:194-202.
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Wakle-Prabagaran M, Lorca RA, Ma X, Stamnes SJ, Amazu C, Hsiao JJ, Karch CM, Hyrc KL, Wright ME, England SK. BKCa channel regulates calcium oscillations induced by alpha-2-macroglobulin in human myometrial smooth muscle cells. Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16):E2335-44.
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Li Y, Lorca RA, Ma X, Rhodes A, England SK. BK channels regulate myometrial contraction by modulating nuclear translocation of NF-?B. Endocrinology. 2014 Aug; 155(8):3112-22.
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Nystoriak MA, Nieves-Cintr?n M, Nygren PJ, Hinke SA, Nichols CB, Chen CY, Puglisi JL, Izu LT, Bers DM, Dell'acqua ML, Scott JD, Santana LF, Navedo MF. AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus. Circ Res. 2014 Feb 14; 114(4):607-15.
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Hypolite JA, Lei Q, Chang S, Zderic SA, Butler S, Wein AJ, Malykhina AP, Chacko S. Spontaneous and evoked contractions are regulated by PKC-mediated signaling in detrusor smooth muscle: involvement of BK channels. Am J Physiol Renal Physiol. 2013 Mar 01; 304(5):F451-62.
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Choudhury S, Garg SK, Singh TU, Mishra SK. Functional and molecular characterization of maxi K+ -channels (BK(Ca)) in buffalo myometrium. Anim Reprod Sci. 2011 Jul; 126(3-4):173-8.
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Mayer CA, Macklin WB, Avishai N, Balan K, Wilson CG, Miller MJ. Mutation in the myelin proteolipid protein gene alters BK and SK channel function in the caudal medulla. Respir Physiol Neurobiol. 2009 Dec 31; 169(3):303-14.
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Kang LS, Kim S, Dominguez JM, Sindler AL, Dick GM, Muller-Delp JM. Aging and muscle fiber type alter K+ channel contributions to the myogenic response in skeletal muscle arterioles. J Appl Physiol (1985). 2009 Aug; 107(2):389-98.
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Resnik E, Herron J, Fu R, Ivy DD, Cornfield DN. Oxygen tension modulates the expression of pulmonary vascular BKCa channel alpha- and beta-subunits. Am J Physiol Lung Cell Mol Physiol. 2006 Apr; 290(4):L761-L768.
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