 Dendrimers
"Dendrimers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tree-like, highly branched, polymeric compounds. They grow three-dimensionally by the addition of shells of branched molecules to a central core. The overall globular shape and presence of cavities gives potential as drug carriers and CONTRAST AGENTS.
| Descriptor ID |
D050091
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| MeSH Number(s) |
D05.750.327 E02.319.300.380.200 J01.637.512.600.200
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| Concept/Terms |
Dendrimers- Dendrimers
- Dendritic Compounds
- Compound, Dendritic
- Dendritic Compound
- Dendrons
- Dendrimer
- Dendritic Polymers
- Dendritic Polymer
- Polymer, Dendritic
- Polymers, Dendritic
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Below are MeSH descriptors whose meaning is more general than "Dendrimers".
Below are MeSH descriptors whose meaning is more specific than "Dendrimers".
This graph shows the total number of publications written about "Dendrimers" by people in this website by year, and whether "Dendrimers" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 1 | 1 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dendrimers" by people in Profiles.
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Lee JG, Petraccione J, Trese KA, Hughes AC, Ausec TR, Salzmann-Sullivan M, Su LJ, Kim MT, Roh S, Goodwin AP, Feng FX, Flaig TW, Shields CW. Soft Extrudable Dendritic Particles with Nanostructured Tendrils for Local Adhesion and Drug Release to Bladder Cancers. Adv Mater. 2025 Sep; 37(38):e2505231.
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Wu LP, Ficker M, Christensen JB, Simberg D, Trohopoulos PN, Moghimi SM. Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking. Nat Commun. 2021 08 11; 12(1):4858.
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Zhang D, Atochina-Vasserman EN, Maurya DS, Huang N, Xiao Q, Ona N, Liu M, Shahnawaz H, Ni H, Kim K, Billingsley MM, Pochan DJ, Mitchell MJ, Weissman D, Percec V. One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA. J Am Chem Soc. 2021 08 11; 143(31):12315-12327.
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Ma W, Fu F, Zhu J, Huang R, Zhu Y, Liu Z, Wang J, Conti PS, Shi X, Chen K. 64Cu-Labeled multifunctional dendrimers for targeted tumor PET imaging. Nanoscale. 2018 Mar 29; 10(13):6113-6124.
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Hodgson SM, McNelles SA, Abdullahu L, Marozas IA, Anseth KS, Adronov A. Reproducible Dendronized PEG Hydrogels via SPAAC Cross-Linking. Biomacromolecules. 2017 Dec 11; 18(12):4054-4059.
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Pryor JB, Harper BJ, Harper SL. Comparative toxicological assessment of PAMAM and thiophosphoryl dendrimers using embryonic zebrafish. Int J Nanomedicine. 2014; 9:1947-56.
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Kullberg M, McCarthy R, Anchordoquy TJ. Systemic tumor-specific gene delivery. J Control Release. 2013 Dec 28; 172(3):730-6.
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Yang H, Tyagi P, Kadam RS, Holden CA, Kompella UB. Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration. ACS Nano. 2012 Sep 25; 6(9):7595-606.
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Zhou J, Neff CP, Liu X, Zhang J, Li H, Smith DD, Swiderski P, Aboellail T, Huang Y, Du Q, Liang Z, Peng L, Akkina R, Rossi JJ. Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice. Mol Ther. 2011 Dec; 19(12):2228-38.
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Holden CA, Tyagi P, Thakur A, Kadam R, Jadhav G, Kompella UB, Yang H. Polyamidoamine dendrimer hydrogel for enhanced delivery of antiglaucoma drugs. Nanomedicine. 2012 Jul; 8(5):776-83.
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