 Polysorbates
"Polysorbates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.
| Descriptor ID |
D011136
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| MeSH Number(s) |
D02.033.455.250.700.690 D05.750.741.700 D25.720.741.700 J01.637.051.720.741.700
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| Concept/Terms |
Polysorbates- Polysorbates
- PSML
- Polyoxyethylene Sorbitan Monolaurate
- Monolaurate, Polyoxyethylene Sorbitan
- Sorbitan Monolaurate, Polyoxyethylene
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Below are MeSH descriptors whose meaning is more general than "Polysorbates".
Below are MeSH descriptors whose meaning is more specific than "Polysorbates".
This graph shows the total number of publications written about "Polysorbates" by people in this website by year, and whether "Polysorbates" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1998 | 3 | 1 | 4 | | 1999 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 1 | 1 | 2 | | 2007 | 0 | 2 | 2 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 3 | 3 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 1 | 2 | | 2019 | 1 | 1 | 2 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 2 | 3 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polysorbates" by people in Profiles.
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Smith CL, Bednarchik B, Aung H, Wilk DJ, Boxer RS, Daddato AE, Wilson BM, Gravenstein S, Canaday DH. Humoral and Cellular Immunity Induced by Adjuvanted and Standard Trivalent Influenza Vaccine in Older Nursing Home Residents. J Infect Dis. 2023 09 15; 228(6):704-714.
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Greenhawt M, Shaker M. Reply to "Polyethylene glycol/polysorbate skin testing can be useful in risk assessment and management of allergic/pseudoallergic reactions to nanolipid/adenoviral vaccines". J Allergy Clin Immunol Pract. 2023 02; 11(2):666-667.
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Greenhawt M, Shaker M, Golden DBK, Abrams EM, Blumenthal KG, Wolfson AR, Stone CA, Krantz MS, Chu DK, Dwamena BA. Diagnostic accuracy of vaccine and vaccine excipient testing in the setting of allergic reactions to COVID-19 vaccines: A?systematic review and meta-analysis. Allergy. 2023 01; 78(1):71-83.
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Zoeller MP, Hafiz S, Marx A, Erwin N, Fricker G, Carpenter JF. Exploring the Protein Stabilizing Capability of Surfactants Against Agitation Stress and the Underlying Mechanisms. J Pharm Sci. 2022 12; 111(12):3261-3274.
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Calderon CP, Krhac Levacic A, Helbig C, Wuchner K, Menzen T. Combining Machine Learning and Backgrounded Membrane Imaging: A Case Study in Comparing and Classifying Different Types of Biopharmaceutically Relevant Particles. J Pharm Sci. 2022 09; 111(9):2422-2434.
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Preston KB, Wong TAS, Lieberman MM, To A, Lai CY, Granados A, Thomasson H, Misamore J, Yalley-Ogunro J, Cabus M, Andersen H, Donini O, Lehrer AT, Randolph TW. Lyophilized Filovirus Glycoprotein Vaccines: Peroxides in a Vaccine Formulation with Polysorbate 80-Containing Adjuvant are Associated with Reduced Neutralizing Antibody Titers in Both Mice and Non-Human Primates. J Pharm Sci. 2022 12; 111(12):3424-3434.
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Greenhawt M, Shaker M, Golden DBK. PEG/Polysorbate Skin Testing Has No Utility in the Assessment of Suspected Allergic Reactions to SARS-CoV-2 Vaccines. J Allergy Clin Immunol Pract. 2021 09; 9(9):3321-3322.
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Kim NA, Kar S, Li Z, Das TK, Carpenter JF. Mimicking Low pH Virus Inactivation Used in Antibody Manufacturing Processes: Effect of Processing Conditions and Biophysical Properties on Antibody Aggregation and Particle Formation. J Pharm Sci. 2021 09; 110(9):3188-3199.
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Wu H, Chisholm CF, Puryear M, Movafaghi S, Smith SD, Pokhilchuk Y, Lengsfeld CS, Randolph TW. Container Surfaces Control Initiation of Cavitation and Resulting Particle Formation in Protein Formulations After Application of Mechanical Shock. J Pharm Sci. 2020 03; 109(3):1270-1280.
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Her C, Carpenter JF. Effects of Tubing Type, Formulation, and Postpumping Agitation on Nanoparticle and Microparticle Formation in Intravenous Immunoglobulin Solutions Processed With a Peristaltic Filling Pump. J Pharm Sci. 2020 01; 109(1):739-749.
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