 Leukemia, Megakaryoblastic, Acute
"Leukemia, Megakaryoblastic, Acute" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acute myeloid leukemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. MYELOFIBROSIS or increased bone marrow RETICULIN is common.
| Descriptor ID |
D007947
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| MeSH Number(s) |
C04.557.337.539.275.450
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| Concept/Terms |
Leukemia, Megakaryoblastic, Acute- Leukemia, Megakaryoblastic, Acute
- Myeloid Leukemia, Acute, M7
- Megakaryocytic Leukemia
- Leukemia, Megakaryocytic, Acute
- Megakaryoblastic Leukemia, Acute
- Acute Megakaryoblastic Leukemia
- Acute Megakaryoblastic Leukemias
- Leukemia, Acute Megakaryoblastic
- Leukemias, Acute Megakaryoblastic
- Megakaryoblastic Leukemias, Acute
- Leukemia, Megakaryocytic
- Leukemias, Megakaryocytic
- Megakaryocytic Leukemias
- Leukemia, Myeloid, Acute, M7
- Megakaryocytic Leukemia, Acute
- Acute Megakaryocytic Leukemia
- Acute Megakaryocytic Leukemias
- Leukemia, Acute Megakaryocytic
- Leukemias, Acute Megakaryocytic
- Megakaryocytic Leukemias, Acute
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Below are MeSH descriptors whose meaning is more general than "Leukemia, Megakaryoblastic, Acute".
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Megakaryoblastic, Acute".
This graph shows the total number of publications written about "Leukemia, Megakaryoblastic, Acute" by people in this website by year, and whether "Leukemia, Megakaryoblastic, Acute" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2005 | 2 | 0 | 2 | | 2007 | 2 | 0 | 2 | | 2012 | 2 | 0 | 2 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukemia, Megakaryoblastic, Acute" by people in Profiles.
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Evans EJ, DeGregori J. Dissecting stepwise mutational impairment of megakaryopoiesis in a model of Down syndrome-associated leukemia. J Clin Invest. 2022 07 15; 132(14).
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Seewald L, Taub JW, Maloney KW, McCabe ER. Acute leukemias in children with Down syndrome. Mol Genet Metab. 2012 Sep; 107(1-2):25-30.
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Liang C, Chan KH, Yoon PJ, Lovell MA. Clinicopathological characteristics of extramedullary acute megakaryoblastic leukemia (AMKL): report of a case with initial mastoid presentation and review of literature to compare extramedullary AMKL and non-AMKL cases. Pediatr Dev Pathol. 2012 Sep-Oct; 15(5):385-92.
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Lee AB, Harker-Murray P, Ferrieri P, Schleiss MR, Tolar J. Bacterial meningitis from Rothia mucilaginosa in patients with malignancy or undergoing hematopoietic stem cell transplantation. Pediatr Blood Cancer. 2008 Mar; 50(3):673-6.
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Pine SR, Guo Q, Yin C, Jayabose S, Druschel CM, Sandoval C. Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome. Blood. 2007 Sep 15; 110(6):2128-31.
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Sandoval C, Pine SR. Down syndrome and GATA1-related transient leukemia. J Pediatr. 2007 Mar; 150(3):e34.
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Pine SR, Guo Q, Yin C, Jayabose S, Levendoglu-Tugal O, Ozkaynak MF, Sandoval C. GATA1 as a new target to detect minimal residual disease in both transient leukemia and megakaryoblastic leukemia of Down syndrome. Leuk Res. 2005 Nov; 29(11):1353-6.
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Sandoval C, Pine SR, Guo Q, Sastry S, Stewart J, Kronn D, Jayabose S. Tetrasomy 21 transient leukemia with a GATA1 mutation in a phenotypically normal trisomy 21 mosaic infant: case report and review of the literature. Pediatr Blood Cancer. 2005 Jan; 44(1):85-91.
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Polski JM, Galambos C, Gale GB, Dunphy CH, Evans HL, Batanian JR. Acute megakaryoblastic leukemia after transient myeloproliferative disorder with clonal karyotype evolution in a phenotypically normal neonate. J Pediatr Hematol Oncol. 2002 Jan; 24(1):50-4.
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Olson JL, May MJ, Stork L, Kadan N, Bateman JB. Acute megakaryoblastic leukemia in Down syndrome: orbital infiltration. Am J Ophthalmol. 2000 Jul; 130(1):128-30.
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