 Receptor, Bradykinin B2
"Receptor, Bradykinin B2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and pain response. It has high specificity for intact forms of BRADYKININ and KALLIDIN. The receptor is coupled to G-PROTEIN, GQ-G11 ALPHA FAMILY and G-PROTEIN, GI-GO ALPHA FAMILY signaling proteins.
| Descriptor ID |
D043782
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| MeSH Number(s) |
D12.776.543.750.695.080.500 D12.776.543.750.720.600.220.500 D12.776.543.750.750.555.220.500
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| Concept/Terms |
Receptor, Bradykinin B2- Receptor, Bradykinin B2
- B2 Receptor, Bradykinin
- Receptor, Bradykinin Type 2
- Bradykinin Type 2 Receptor
- Bradykinin B2 Receptors
- B2 Receptors, Bradykinin
- Receptors, Bradykinin B2
- Bradykinin B2 Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptor, Bradykinin B2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Bradykinin [D12.776.543.750.695.080]
- Receptor, Bradykinin B2 [D12.776.543.750.695.080.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Bradykinin [D12.776.543.750.720.600.220]
- Receptor, Bradykinin B2 [D12.776.543.750.720.600.220.500]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Bradykinin [D12.776.543.750.750.555.220]
- Receptor, Bradykinin B2 [D12.776.543.750.750.555.220.500]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Bradykinin B2".
This graph shows the total number of publications written about "Receptor, Bradykinin B2" by people in this website by year, and whether "Receptor, Bradykinin B2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Bradykinin B2" by people in Profiles.
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Marceau F, Bawolak MT, Fortin JP, Morissette G, Roy C, Bachelard H, Gera L, Charest-Morin X. Bifunctional ligands of the bradykinin B2 and B1 receptors: An exercise in peptide hormone plasticity. Peptides. 2018 07; 105:37-50.
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Moran CS, Rush CM, Dougan T, Jose RJ, Biros E, Norman PE, Gera L, Golledge J. Modulation of Kinin B2 Receptor Signaling Controls Aortic Dilatation and Rupture in the Angiotensin II-Infused Apolipoprotein E-Deficient Mouse. Arterioscler Thromb Vasc Biol. 2016 05; 36(5):898-907.
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Gera L, Roy C, Charest-Morin X, Marceau F. Vasopeptidase-activated latent ligands of the histamine receptor-1. Int Immunopharmacol. 2013 Nov; 17(3):677-83.
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Gera L, Roy C, Marceau F. Bifunctional epitope-agonist ligands of the bradykinin B(2) receptor. Biol Chem. 2013 Mar; 394(3):379-83.
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Charest-Morin X, Fortin S, Lodge R, Roy C, Gera L, Gaudreault RC, Marceau F. Inhibitory effects of cytoskeleton disrupting drugs and GDP-locked Rab mutants on bradykinin B2 receptor cycling. Pharmacol Res. 2013 May; 71:44-52.
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Bawolak MT, Roy C, Gera L, Marceau F. Prolonged signalling and trafficking of the bradykinin B2 receptor stimulated with the amphibian peptide maximakinin: insight into the endosomal inactivation of kinins. Pharmacol Res. 2012 Feb; 65(2):247-53.
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Gera L, Bawolak MT, Roy C, Lodge R, Marceau F. Design of fluorescent bradykinin analogs: application to imaging of B2 receptor-mediated agonist endocytosis and trafficking and angiotensin-converting enzyme. J Pharmacol Exp Ther. 2011 Apr; 337(1):33-41.
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Marceau F, deBlois D, Petitclerc E, Levesque L, Drapeau G, Audet R, Godin D, Larriv?e JF, Houle S, Sabourin T, Fortin JP, Morissette G, Gera L, Bawolak MT, Koumbadinga GA, Bouthillier J. Vascular smooth muscle contractility assays for inflammatory and immunological mediators. Int Immunopharmacol. 2010 Nov; 10(11):1344-53.
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Bawolak MT, Fortin S, Bouthillier J, Adam A, Gera L, C-Gaudreault R, Marceau F. Effects of inactivation-resistant agonists on the signalling, desensitization and down-regulation of bradykinin B(2) receptors. Br J Pharmacol. 2009 Nov; 158(5):1375-86.
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Bawolak MT, Gera L, Morissette G, Stewart JM, Marceau F. B-9972 (D-Arg-[Hyp3,Igl5,Oic7,Igl8]-bradykinin) is an inactivation-resistant agonist of the bradykinin B2 receptor derived from the peptide antagonist B-9430 (D-Arg-[Hyp3,Igl5,D-Igl7,Oic8]-bradykinin): pharmacologic profile and effective induction of receptor degradation. J Pharmacol Exp Ther. 2007 Nov; 323(2):534-46.
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