 Receptor, Bradykinin B1
"Receptor, Bradykinin B1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of BRADYKININ RECEPTOR that is induced in response to INFLAMMATION. It may play a role in chronic inflammation and has a high specificity for KININS lacking the C-terminal ARGININE such as des-Arg(10)-kallidin and des-Arg(9)-bradykinin. The receptor is coupled to G-PROTEIN, GQ-G11 ALPHA FAMILY and G-PROTEIN, GI-GO ALPHA FAMILY signaling proteins.
| Descriptor ID |
D043783
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| MeSH Number(s) |
D12.776.543.750.695.080.249 D12.776.543.750.720.600.220.249 D12.776.543.750.750.555.220.249
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| Concept/Terms |
Receptor, Bradykinin B1- Receptor, Bradykinin B1
- Bradykinin Type 1 Receptor
- Bradykinin B1 Receptor
- Bradykinin B1 Receptors
- Receptors, Bradykinin B1
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Below are MeSH descriptors whose meaning is more general than "Receptor, Bradykinin B1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Bradykinin [D12.776.543.750.695.080]
- Receptor, Bradykinin B1 [D12.776.543.750.695.080.249]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Bradykinin [D12.776.543.750.720.600.220]
- Receptor, Bradykinin B1 [D12.776.543.750.720.600.220.249]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Bradykinin [D12.776.543.750.750.555.220]
- Receptor, Bradykinin B1 [D12.776.543.750.750.555.220.249]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Bradykinin B1".
This graph shows the total number of publications written about "Receptor, Bradykinin B1" by people in this website by year, and whether "Receptor, Bradykinin B1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Bradykinin B1" by people in Profiles.
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Marceau F, Bawolak MT, Fortin JP, Morissette G, Roy C, Bachelard H, Gera L, Charest-Morin X. Bifunctional ligands of the bradykinin B2 and B1 receptors: An exercise in peptide hormone plasticity. Peptides. 2018 07; 105:37-50.
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Roy C, Marceau E, Gera L, Marceau F. An in vitro reconstitution system to address the mechanism of the vascular expression of the bradykinin B1 receptor in response to angiotensin converting enzyme inhibition. Vascul Pharmacol. 2012 Aug 19; 57(1):15-23.
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Bawolak MT, Gera L, Morissette G, Bouthillier J, Stewart JM, Gobeil LA, Lodge R, Adam A, Marceau F. Fluorescent ligands of the bradykinin B1 receptors: pharmacologic characterization and application to the study of agonist-induced receptor translocation and cell surface receptor expression. J Pharmacol Exp Ther. 2009 Apr; 329(1):159-68.
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Bawolak MT, Gera L, Bouthillier J, Stewart JM, Adam A, Marceau F. A fluorescent version of the bradykinin B2 receptor antagonist B-9430: pharmacological characterization and use in live cell imaging. Peptides. 2008 Sep; 29(9):1626-30.
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Morissette G, Houle S, Gera L, Stewart JM, Marceau F. Antagonist, partial agonist and antiproliferative actions of B-9870 (CU201) as a function of the expression and density of the bradykinin B1 and B2 receptors. Br J Pharmacol. 2007 Feb; 150(3):369-79.
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DomBourian MG, Turner NA, Gerovac TA, Vemuganti R, Miranpuri GS, T?reyen K, Satriotomo I, Miletic V, Resnick DK. B1 and TRPV-1 receptor genes and their relationship to hyperalgesia following spinal cord injury. Spine (Phila Pa 1976). 2006 Nov 15; 31(24):2778-82.
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Fortin JP, Gera L, Bouthillier J, Stewart JM, Adam A, Marceau F. Endogenous aminopeptidase N decreases the potency of peptide agonists and antagonists of the kinin B1 receptors in the rabbit aorta. J Pharmacol Exp Ther. 2005 Sep; 314(3):1169-76.
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Tsch?pe C, Spillmann F, Altmann C, Koch M, Westermann D, Dhayat N, Dhayat S, Bascands JL, Gera L, Hoffmann S, Schultheiss HP, Walther T. The bradykinin B1 receptor contributes to the cardioprotective effects of AT1 blockade after experimental myocardial infarction. Cardiovasc Res. 2004 Feb 15; 61(3):559-69.
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Larriv?e JF, Gera L, Houle S, Bouthillier J, Bachvarov DR, Stewart JM, Marceau F. Non-competitive pharmacological antagonism at the rabbit B(1) receptor. Br J Pharmacol. 2000 Nov; 131(5):885-92.
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Sejbal J, Wang Y, Cann JR, Stewart JM, Gera L, Kotovych G. A comparative NMR and molecular dynamics study of the conformations of bradykinin B1 and B2, B2, and B1-specific receptor antagonists B-9430, B-9436, and B-9858. Biopolymers. 1997 Oct 15; 42(5):521-35.
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