Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia.

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Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia.

Netea MG, Fantuzzi G, Kullberg BJ, Stuyt RJ, Pulido EJ, McIntyre RC, Joosten LA, Van der Meer JW, Dinarello CA. Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia. J Immunol. 2000 Mar 01; 164(5):2644-9.

View in: PubMed

subject areas

Animals
Cell Movement
Chemokines
Endotoxemia
Escherichia coli Infections
Immune Sera
Injections, Intraperitoneal
Interferon-gamma
Interleukin-18
Lipopolysaccharides
Liver
Lung
Mice
Mice, Inbred C57BL
Mice, Knockout
Neutrophils
Peroxidase
Salmonella Infections, Animal
Salmonella typhimurium
Tumor Necrosis Factor-alpha

authors with profiles

Charles A Dinarello

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