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Aaron Whiteley

TitleAsst Professor
InstitutionUniversity of Colorado Boulder
DepartmentBiochemistry

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Govande AA, Duncan-Lowey B, Eaglesham JB, Whiteley AT, Kranzusch PJ. Molecular basis of CD-NTase nucleotide selection in CBASS anti-phage defense. Cell Rep. 2021 Jun 01; 35(9):109206. PMID: 34077735.
      View in: PubMed
    2. Kibby EM, Whiteley AT. The Linguistics of Bacterial Conflict Systems Reveal Ancient Origins of Eukaryotic Innate Immunity. J Bacteriol. 2020 11 19; 202(24). PMID: 32958633.
      View in: PubMed
    3. Chang D, Whiteley AT, Bugda Gwilt K, Lencer WI, Mekalanos JJ, Thiagarajah JR. Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling. Proc Natl Acad Sci U S A. 2020 11 03; 117(44):27502-27508. PMID: 33087577.
      View in: PubMed
    4. Peterson BN, Young MKM, Luo S, Wang J, Whiteley AT, Woodward JJ, Tong L, Wang JD, Portnoy DA. (p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes. mBio. 2020 08 25; 11(4). PMID: 32843560.
      View in: PubMed
    5. Lowey B, Whiteley AT, Keszei AFA, Morehouse BR, Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P, Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY, Kranzusch PJ. CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection. Cell. 2020 07 09; 182(1):38-49.e17. PMID: 32544385.
      View in: PubMed
    6. Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews IT, Watrous JD, Ego K, Whiteley AT, Lowey B, Mekalanos JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD. Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity. Mol Cell. 2020 02 20; 77(4):723-733.e6. PMID: 31932164.
      View in: PubMed
    7. Zhou W, Whiteley AT, Kranzusch PJ. Analysis of human cGAS activity and structure. Methods Enzymol. 2019; 625:13-40. PMID: 31455523.
      View in: PubMed
    8. Whiteley AT, Eaglesham JB, de Oliveira Mann CC, Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King DS, Lee ASY, Mekalanos JJ, Kranzusch PJ. Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature. 2019 03; 567(7747):194-199. PMID: 30787435.
      View in: PubMed
    9. Zhou W, Whiteley AT, de Oliveira Mann CC, Morehouse BR, Nowak RP, Fischer ES, Gray NS, Mekalanos JJ, Kranzusch PJ. Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance. Cell. 2018 07 12; 174(2):300-311.e11. PMID: 30007416.
      View in: PubMed
    10. Mitchell G, Cheng MI, Chen C, Nguyen BN, Whiteley AT, Kianian S, Cox JS, Green DR, McDonald KL, Portnoy DA. Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):E210-E217. PMID: 29279409.
      View in: PubMed
    11. Portman JL, Dubensky SB, Peterson BN, Whiteley AT, Portnoy DA. Activation of the Listeria monocytogenes Virulence Program by a Reducing Environment. mBio. 2017 10 17; 8(5). PMID: 29042499.
      View in: PubMed
    12. Whiteley AT, Ruhland BR, Edrozo MB, Reniere ML. A Redox-Responsive Transcription Factor Is Critical for Pathogenesis and Aerobic Growth of Listeria monocytogenes. Infect Immun. 2017 05; 85(5). PMID: 28193635.
      View in: PubMed
    13. Whiteley AT, Garelis NE, Peterson BN, Choi PH, Tong L, Woodward JJ, Portnoy DA. c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation. Mol Microbiol. 2017 04; 104(2):212-233. PMID: 28097715.
      View in: PubMed
    14. Reniere ML, Whiteley AT, Portnoy DA. An In Vivo Selection Identifies Listeria monocytogenes Genes Required to Sense the Intracellular Environment and Activate Virulence Factor Expression. PLoS Pathog. 2016 07; 12(7):e1005741. PMID: 27414028.
      View in: PubMed
    15. Whiteley AT, Pollock AJ, Portnoy DA. The PAMP c-di-AMP Is Essential for Listeria monocytogenes Growth in Rich but Not Minimal Media due to a Toxic Increase in (p)ppGpp. [corrected]. . 2015 Jun 10; 17(6):788-98. PMID: 26028365.
      View in: PubMed
    16. Kellenberger CA, Chen C, Whiteley AT, Portnoy DA, Hammond MC. RNA-Based Fluorescent Biosensors for Live Cell Imaging of Second Messenger Cyclic di-AMP. J Am Chem Soc. 2015 May 27; 137(20):6432-5. PMID: 25965978.
      View in: PubMed
    17. Reniere ML, Whiteley AT, Hamilton KL, John SM, Lauer P, Brennan RG, Portnoy DA. Glutathione activates virulence gene expression of an intracellular pathogen. Nature. 2015 Jan 08; 517(7533):170-3. PMID: 25567281.
      View in: PubMed
    18. Witte CE, Whiteley AT, Burke TP, Sauer JD, Portnoy DA, Woodward JJ. Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection. mBio. 2013 May 28; 4(3):e00282-13. PMID: 23716572.
      View in: PubMed
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