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Jessica Lynne Jones-Carson

TitleClinical Instructor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Immunology Microbiology

    Collapse Research 
    Collapse research activities and funding
    K01RR016082     (JONES-CARSON, JESSICA L)Apr 1, 2001 - Mar 31, 2007
    Systemic immunity induced by mucosal CD18+ cells
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tapscott T, Kim JS, Crawford MA, Fitzsimmons L, Liu L, Jones-Carson J, Vázquez-Torres A. Guanosine tetraphosphate relieves the negative regulation of Salmonella pathogenicity island-2 gene transcription exerted by the AT-rich ssrA discriminator region. Sci Rep. 2018 Jun 21; 8(1):9465. PMID: 29930310.
      View in: PubMed
    2. Fitzsimmons LF, Liu L, Kim JS, Jones-Carson J, Vázquez-Torres A. Salmonella Reprograms Nucleotide Metabolism in Its Adaptation to Nitrosative Stress. MBio. 2018 02 27; 9(1). PMID: 29487237.
      View in: PubMed
    3. Jones-Carson J, Husain M, Liu L, Orlicky DJ, Vázquez-Torres A. Cytochrome bd-Dependent Bioenergetics and Antinitrosative Defenses in Salmonella Pathogenesis. MBio. 2016 12 20; 7(6). PMID: 27999164.
      View in: PubMed
    4. Jones-Carson J, Zweifel AE, Tapscott T, Austin C, Brown JM, Jones KL, Voskuil MI, Vázquez-Torres A. Nitric oxide from IFN?-primed macrophages modulates the antimicrobial activity of ß-lactams against the intracellular pathogens Burkholderia pseudomallei and Nontyphoidal Salmonella. PLoS Negl Trop Dis. 2014 Aug; 8(8):e3079. PMID: 25121731; PMCID: PMC4133387.
    5. Husain M, Jones-Carson J, Liu L, Song M, Saah JR, Troxell B, Mendoza M, Hassan H, Vázquez-Torres A. Ferric uptake regulator-dependent antinitrosative defenses in Salmonella enterica serovar Typhimurium pathogenesis. Infect Immun. 2014 Jan; 82(1):333-40. PMID: 24166960; PMCID: PMC3911868.
    6. Song M, Husain M, Jones-Carson J, Liu L, Henard CA, Vázquez-Torres A. Low-molecular-weight thiol-dependent antioxidant and antinitrosative defences in Salmonella pathogenesis. Mol Microbiol. 2013 Feb; 87(3):609-22. PMID: 23217033; PMCID: PMC3885168.
    7. Jones-Carson J, Laughlin JR, Stewart AL, Voskuil MI, Vázquez-Torres A. Nitric oxide-dependent killing of aerobic, anaerobic and persistent Burkholderia pseudomallei. Nitric Oxide. 2012 Jun 30; 27(1):25-31. PMID: 22521523; PMCID: PMC3517295.
    8. Zajdowicz SL, Jones-Carson J, Vazquez-Torres A, Jobling MG, Gill RE, Holmes RK. Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker. PLoS One. 2011; 6(6):e21523. PMID: 21720554; PMCID: PMC3123353.
    9. Evans MR, Fink RC, Vazquez-Torres A, Porwollik S, Jones-Carson J, McClelland M, Hassan HM. Analysis of the ArcA regulon in anaerobically grown Salmonella enterica sv. Typhimurium. BMC Microbiol. 2011 Mar 21; 11:58. PMID: 21418628; PMCID: PMC3075218.
    10. Troxell B, Sikes ML, Fink RC, Vazquez-Torres A, Jones-Carson J, Hassan HM. Fur negatively regulates hns and is required for the expression of HilA and virulence in Salmonella enterica serovar Typhimurium. J Bacteriol. 2011 Jan; 193(2):497-505. PMID: 21075923; PMCID: PMC3019815.
    11. Husain M, Jones-Carson J, Song M, McCollister BD, Bourret TJ, Vázquez-Torres A. Redox sensor SsrB Cys203 enhances Salmonella fitness against nitric oxide generated in the host immune response to oral infection. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14396-401. PMID: 20660761; PMCID: PMC2922535.
    12. Jones-Carson J, Laughlin J, Hamad MA, Stewart AL, Voskuil MI, Vázquez-Torres A. Inactivation of [Fe-S] metalloproteins mediates nitric oxide-dependent killing of Burkholderia mallei. PLoS One. 2008 Apr 09; 3(4):e1976. PMID: 18398486; PMCID: PMC2276317.
    13. Husain M, Bourret TJ, McCollister BD, Jones-Carson J, Laughlin J, Vázquez-Torres A. Nitric oxide evokes an adaptive response to oxidative stress by arresting respiration. J Biol Chem. 2008 Mar 21; 283(12):7682-9. PMID: 18198179.
      View in: PubMed
    14. Vazquez-Torres A, Stevanin T, Jones-Carson J, Castor M, Read RC, Fang FC. Analysis of nitric oxide-dependent antimicrobial actions in macrophages and mice. Methods Enzymol. 2008; 437:521-38. PMID: 18433645; PMCID: PMC2704381.
    15. McCollister BD, Myers JT, Jones-Carson J, Husain M, Bourret TJ, Vázquez-Torres A. N(2)O(3) enhances the nitrosative potential of IFNgamma-primed macrophages in response to Salmonella. Immunobiology. 2007; 212(9-10):759-69. PMID: 18086377; PMCID: PMC2329578.
    16. McCollister BD, Myers JT, Jones-Carson J, Voelker DR, Vázquez-Torres A. Constitutive acid sphingomyelinase enhances early and late macrophage killing of Salmonella enterica serovar Typhimurium. Infect Immun. 2007 Nov; 75(11):5346-52. PMID: 17698574; PMCID: PMC2168317.
    17. Jones-Carson J, McCollister BD, Clambey ET, Vázquez-Torres A. Systemic CD8 T-cell memory response to a Salmonella pathogenicity island 2 effector is restricted to Salmonella enterica encountered in the gastrointestinal mucosa. Infect Immun. 2007 Jun; 75(6):2708-16. PMID: 17403871; PMCID: PMC1932863.
    18. Fink RC, Evans MR, Porwollik S, Vazquez-Torres A, Jones-Carson J, Troxell B, Libby SJ, McClelland M, Hassan HM. FNR is a global regulator of virulence and anaerobic metabolism in Salmonella enterica serovar Typhimurium (ATCC 14028s). J Bacteriol. 2007 Mar; 189(6):2262-73. PMID: 17220229; PMCID: PMC1899381.
    19. McCollister BD, Bourret TJ, Gill R, Jones-Carson J, Vázquez-Torres A. Repression of SPI2 transcription by nitric oxide-producing, IFNgamma-activated macrophages promotes maturation of Salmonella phagosomes. J Exp Med. 2005 Sep 05; 202(5):625-35. PMID: 16129704; PMCID: PMC2212872.
    20. Jones-Carson J, Fantuzzi G, Siegmund B, Dinarello C, Tracey KJ, Wang H, Fang FC, Vazquez-Torres A. Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock. J Infect Dis. 2005 Sep 15; 192(6):1039-46. PMID: 16107957.
      View in: PubMed
    21. Siegmund B, Sennello JA, Jones-Carson J, Gamboni-Robertson F, Lehr HA, Batra A, Fedke I, Zeitz M, Fantuzzi G. Leptin receptor expression on T lymphocytes modulates chronic intestinal inflammation in mice. Gut. 2004 Jul; 53(7):965-72. PMID: 15194645; PMCID: PMC1774108.
    22. Vazquez-Torres A, Vallance BA, Bergman MA, Finlay BB, Cookson BT, Jones-Carson J, Fang FC. Toll-like receptor 4 dependence of innate and adaptive immunity to Salmonella: importance of the Kupffer cell network. J Immunol. 2004 May 15; 172(10):6202-8. PMID: 15128808.
      View in: PubMed
    23. Testerman TL, Vazquez-Torres A, Xu Y, Jones-Carson J, Libby SJ, Fang FC. The alternative sigma factor sigmaE controls antioxidant defences required for Salmonella virulence and stationary-phase survival. Mol Microbiol. 2002 Feb; 43(3):771-82. PMID: 11929531.
      View in: PubMed
    24. Vazquez-Torres A, Jones-Carson J, Mastroeni P, Ischiropoulos H, Fang FC. Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro. J Exp Med. 2000 Jul 17; 192(2):227-36. PMID: 10899909.
      View in: PubMed
    25. Jones-Carson J, Vazquez-Torres A, Warner T, Balish E. Disparate requirement for T cells in resistance to mucosal and acute systemic candidiasis. Infect Immun. 2000 Apr; 68(4):2363-5. PMID: 10722645; PMCID: PMC97429.
    26. Vazquez-Torres A, Xu Y, Jones-Carson J, Holden DW, Lucia SM, Dinauer MC, Mastroeni P, Fang FC. Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase. Science. 2000 Mar 03; 287(5458):1655-8. PMID: 10698741.
      View in: PubMed
    27. Faggioni R, Jones-Carson J, Reed DA, Dinarello CA, Feingold KR, Grunfeld C, Fantuzzi G. Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18. Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5):2367-72. PMID: 10681432; PMCID: PMC15807.
    28. Vazquez-Torres A, Jones-Carson J, Bäumler AJ, Falkow S, Valdivia R, Brown W, Le M, Berggren R, Parks WT, Fang FC. Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes. Nature. 1999 Oct 21; 401(6755):804-8. PMID: 10548107.
      View in: PubMed
    29. Kench JA, Russell DM, Fadok VA, Young SK, Worthen GS, Jones-Carson J, Henson JE, Henson PM, Nemazee D. Aberrant wound healing and TGF-beta production in the autoimmune-prone MRL/+ mouse. Clin Immunol. 1999 Sep; 92(3):300-10. PMID: 10479535.
      View in: PubMed
    30. Balish E, Wagner RD, Vazquez-Torres A, Jones-Carson J, Pierson C, Warner T. Mucosal and systemic candidiasis in IL-8Rh-/- BALB/c mice. J Leukoc Biol. 1999 Jul; 66(1):144-50. PMID: 10411002.
      View in: PubMed
    31. Vazquez-Torres A, Jones-Carson J, Wagner RD, Warner T, Balish E. Early resistance of interleukin-10 knockout mice to acute systemic candidiasis. Infect Immun. 1999 Feb; 67(2):670-4. PMID: 9916075; PMCID: PMC96371.
    32. Born W, Cady C, Jones-Carson J, Mukasa A, Lahn M, O'Brien R. Immunoregulatory functions of gamma delta T cells. Adv Immunol. 1999; 71:77-144. PMID: 9917911.
      View in: PubMed
    33. Jones-Carson J, Balish E, Uehling DT. Susceptibility of immunodeficient gene-knockout mice to urinary tract infection. J Urol. 1999 Jan; 161(1):338-41. PMID: 10037434.
      View in: PubMed
    34. Jones-Carson J, Vazquez-Torres FA, Balish E. B cell-independent selection of memory T cells after mucosal immunization with Candida albicans. J Immunol. 1997 May 01; 158(9):4328-35. PMID: 9126995.
      View in: PubMed
    35. Boivin GP, Ormsby I, Jones-Carson J, O'Toole BA, Doetschman T. Germ-free and barrier-raised TGF beta 1-deficient mice have similar inflammatory lesions. Transgenic Res. 1997 May; 6(3):197-202. PMID: 9167267.
      View in: PubMed
    36. Balish E, Vazquez-Torres FA, Jones-Carson J, Wagner RD, Warner T. Importance of beta2-microglobulin in murine resistance to mucosal and systemic candidiasis. Infect Immun. 1996 Dec; 64(12):5092-7. PMID: 8945551; PMCID: PMC174493.
    37. Wagner RD, Vazquez-Torres A, Jones-Carson J, Warner T, Balish E. B cell knockout mice are resistant to mucosal and systemic candidiasis of endogenous origin but susceptible to experimental systemic candidiasis. J Infect Dis. 1996 Sep; 174(3):589-97. PMID: 8769618.
      View in: PubMed
    38. Vazquez-Torres A, Jones-Carson J, Balish E. Peroxynitrite contributes to the candidacidal activity of nitric oxide-producing macrophages. Infect Immun. 1996 Aug; 64(8):3127-33. PMID: 8757843; PMCID: PMC174197.
    39. Vazquez-Torres A, Jones-Carson J, Warner T, Balish E. Nitric oxide enhances resistance of SCID mice to mucosal candidiasis. J Infect Dis. 1995 Jul; 172(1):192-8. PMID: 7541062.
      View in: PubMed
    40. Jones-Carson J, Vazquez-Torres A, Balish E. Defective killing of Candida albicans hyphae by neutrophils from beige mice. J Infect Dis. 1995 Jun; 171(6):1664-7. PMID: 7769315.
      View in: PubMed
    41. Jones-Carson J, Vazquez-Torres A, van der Heyde HC, Warner T, Wagner RD, Balish E. Gamma delta T cell-induced nitric oxide production enhances resistance to mucosal candidiasis. Nat Med. 1995 Jun; 1(6):552-7. PMID: 7585122.
      View in: PubMed
    42. Vazquez-Torres A, Jones-Carson J, Balish E. Nitric oxide production does not directly increase macrophage candidacidal activity. Infect Immun. 1995 Mar; 63(3):1142-4. PMID: 7868241; PMCID: PMC173125.
    43. Vazquez-Torres A, Jones-Carson J, Balish E. Candidacidal activity of macrophages from immunocompetent and congenitally immunodeficient mice. J Infect Dis. 1994 Jul; 170(1):180-8. PMID: 8014495.
      View in: PubMed
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