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Sally P Stabler

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-4086

    Collapse Research 
    Collapse research activities and funding
    F32GM009968     (STABLER, SALLY P)Jan 10, 1985
    NIH/NIGMS
    CHARACTERIZATION OF D, L-METHYLMALONYL-COA RACEMASE
    Role: Principal Investigator

    R01DK037165     (STABLER, SALLY P)Apr 15, 1986 - Mar 31, 1989
    NIH/NIDDK
    METABOLIC ASPECTS OF COBALAMIN AND FOLATE PATHWAYS
    Role: Principal Investigator

    R01AG009834     (STABLER, SALLY P)Jun 1, 1991 - Jun 30, 2009
    NIH/NIA
    B12 Nutrition in the Aged
    Role: Principal Investigator

    R13DK103410     (STABLER, SALLY P)Jun 1, 2014 - May 31, 2015
    NIH/NIDDK
    FASEB SRC on Folic Acid, Vitamin B12 and One Carbon Metabolism
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Maclean KN, Jiang H, Aivazidis S, Kim E, Shearn CT, Harris PS, Petersen DR, Allen RH, Stabler SP, Roede JR. Taurine treatment prevents derangement of the hepatic ?-glutamyl cycle and methylglyoxal metabolism in a mouse model of classical homocystinuria: regulatory crosstalk between thiol and sulfinic acid metabolism. FASEB J. 2017 Nov 03. PMID: 29101223.
      View in: PubMed
    2. Green R, Allen LH, Bjørke-Monsen AL, Brito A, Guéant JL, Miller JW, Molloy AM, Nexo E, Stabler S, Toh BH, Ueland PM, Yajnik C. Vitamin B12 deficiency. Nat Rev Dis Primers. 2017 Jun 29; 3:17040. PMID: 28660890.
      View in: PubMed
    3. Stabler SP, Freehauf C, Allen RH, Thomas J, Gallagher R. Potential Misdiagnosis of Hyperhomocysteinemia due to Cystathionine Beta-Synthase Deficiency During Pregnancy. JIMD Rep. 2017 Mar 09. PMID: 28275971.
      View in: PubMed
    4. Tang YS, Khan RA, Xiao S, Hansen DK, Stabler SP, Kusumanchi P, Jayaram HN, Antony AC. Evidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells. J Nutr. 2017 Apr; 147(4):482-498. PMID: 28250194.
      View in: PubMed
    5. Kelly KB, Kennelly JP, Ordonez M, Nelson R, Leonard K, Stabler S, Gomez-Muñoz A, Field CJ, Jacobs RL. Excess Folic Acid Increases Lipid Storage, Weight Gain, and Adipose Tissue Inflammation in High Fat Diet-Fed Rats. Nutrients. 2016 Sep 23; 8(10). PMID: 27669293.
      View in: PubMed
    6. Sørensen JT, Gaustadnes M, Stabler SP, Allen RH, Mudd SH, Hvas AM. Molecular and biochemical investigations of patients with intermediate or severe hyperhomocysteinemia. Mol Genet Metab. 2016 Mar; 117(3):344-50. PMID: 26750749.
      View in: PubMed
    7. Chien YH, Abdenur JE, Baronio F, Bannick AA, Corrales F, Couce M, Donner MG, Ficicioglu C, Freehauf C, Frithiof D, Gotway G, Hirabayashi K, Hofstede F, Hoganson G, Hwu WL, James P, Kim S, Korman SH, Lachmann R, Levy H, Lindner M, Lykopoulou L, Mayatepek E, Muntau A, Okano Y, Raymond K, Rubio-Gozalbo E, Scholl-Bürgi S, Schulze A, Singh R, Stabler S, Stuy M, Thomas J, Wagner C, Wilson WG, Wortmann S, Yamamoto S, Pao M, Blom HJ. Mudd's disease (MAT I/III deficiency): a survey of data for MAT1A homozygotes and compound heterozygotes. Orphanet J Rare Dis. 2015 Aug 20; 10:99. PMID: 26289392; PMCID: PMC4545930.
    8. Jiang H, Hurt KJ, Breen K, Stabler SP, Allen RH, Orlicky DJ, Maclean KN. Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap. Biol Open. 2015 Aug 14; 4(9):1154-62. PMID: 26276101; PMCID: PMC4582125.
    9. Blatch SA, Stabler SP, Harrison JF. The effects of folate intake on DNA and single-carbon pathway metabolism in the fruit fly Drosophila melanogaster compared to mammals. Comp Biochem Physiol B Biochem Mol Biol. 2015 Nov; 189:34-9. PMID: 26219578.
      View in: PubMed
    10. Bae S, West AA, Yan J, Jiang X, Perry CA, Malysheva O, Stabler SP, Allen RH, Caudill MA. Vitamin B-12 Status Differs among Pregnant, Lactating, and Control Women with Equivalent Nutrient Intakes. J Nutr. 2015 Jul; 145(7):1507-14. PMID: 25995278.
      View in: PubMed
    11. Davenport C, Yan J, Taesuwan S, Shields K, West AA, Jiang X, Perry CA, Malysheva OV, Stabler SP, Allen RH, Caudill MA. Choline intakes exceeding recommendations during human lactation improve breast milk choline content by increasing PEMT pathway metabolites. J Nutr Biochem. 2015 Sep; 26(9):903-11. PMID: 26025328.
      View in: PubMed
    12. Blom HJ, Stabler S, Wagner C. In memoriam: S. Harvey Mudd. Am J Med Genet A. 2015 May; 167A(5):994-6. PMID: 25820490.
      View in: PubMed
    13. Kurnat-Thoma EL, Pangilinan F, Matteini AM, Wong B, Pepper GA, Stabler SP, Guralnik JM, Brody LC. Association of Transcobalamin II (TCN2) and Transcobalamin II-Receptor (TCblR) Genetic Variations With Cobalamin Deficiency Parameters in Elderly Women. Biol Res Nurs. 2015 Jul; 17(4):444-54. PMID: 25657319.
      View in: PubMed
    14. Stabler SP. Anemias due to essential nutrient deficiencies. World Rev Nutr Diet. 2015; 111:164-8. PMID: 25418407.
      View in: PubMed
    15. Quintana AM, Geiger EA, Achilly N, Rosenblatt DS, Maclean KN, Stabler SP, Artinger KB, Appel B, Shaikh TH. Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating mmachc expression. Dev Biol. 2014 Dec 01; 396(1):94-106. PMID: 25281006; PMCID: PMC4391465.
    16. Brito A, Chiquette J, Stabler SP, Allen RH, Girard CL. Supplementing lactating dairy cows with a vitamin B12 precursor, 5,6-dimethylbenzimidazole, increases the apparent ruminal synthesis of vitamin B12. Animal. 2015 Jan; 9(1):67-75. PMID: 25171056.
      View in: PubMed
    17. Jiang H, Stabler SP, Allen RH, Abman SH, Maclean KN. Altered hepatic sulfur metabolism in cystathionine ß-synthase-deficient homocystinuria: regulatory role of taurine on competing cysteine oxidation pathways. FASEB J. 2014 Sep; 28(9):4044-54. PMID: 24891521.
      View in: PubMed
    18. Yan J, Jiang X, West AA, Perry CA, Malysheva OV, Brenna JT, Stabler SP, Allen RH, Gregory JF, Caudill MA. Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women. Am J Clin Nutr. 2013 Dec; 98(6):1459-67. PMID: 24132975.
      View in: PubMed
    19. Joachim E, Goldenberg NA, Bernard TJ, Armstrong-Wells J, Stabler S, Manco-Johnson MJ. The methylenetetrahydrofolate reductase polymorphism (MTHFR c.677C>T) and elevated plasma homocysteine levels in a U.S. pediatric population with incident thromboembolism. Thromb Res. 2013 Aug; 132(2):170-4. PMID: 23866722; PMCID: PMC4115647.
    20. Stabler SP, Korson M, Jethva R, Allen RH, Kraus JP, Spector EB, Wagner C, Mudd SH. Metabolic profiling of total homocysteine and related compounds in hyperhomocysteinemia: utility and limitations in diagnosing the cause of puzzling thrombophilia in a family. JIMD Rep. 2013; 11:149-63. PMID: 23733603; PMCID: PMC3755560.
    21. Stabler SP. Vitamin B12 deficiency. N Engl J Med. 2013 May 23; 368(21):2041-2. PMID: 23697526.
      View in: PubMed
    22. Abarinov EV, Beaudin AE, Field MS, Perry CA, Allen RH, Stabler SP, Stover PJ. Disruption of shmt1 impairs hippocampal neurogenesis and mnemonic function in mice. J Nutr. 2013 Jul; 143(7):1028-35. PMID: 23700346; PMCID: PMC3681542.
    23. Delaney C, Garg SK, Fernandes C, Hoeltzel M, Allen RH, Stabler S, Yung R. Maternal diet supplemented with methyl-donors protects against atherosclerosis in F1 ApoE(-/-) mice. PLoS One. 2013; 8(2):e56253. PMID: 23437105; PMCID: PMC3578836.
    24. Stabler SP. Clinical practice. Vitamin B12 deficiency. N Engl J Med. 2013 Jan 10; 368(2):149-60. PMID: 23301732.
      View in: PubMed
    25. Davey A, Dai T, Woodard JL, Miller LS, Gondo Y, Johnson MA, Hausman DB, Martin P, Green RC, Allen RH, Stabler SP, Poon LW. Profiles of cognitive functioning in a population-based sample of centenarians using factor mixture analysis. Exp Aging Res. 2013; 39(2):125-44. PMID: 23421635; PMCID: PMC3579538.
    26. Field MS, Shields KS, Abarinov EV, Malysheva OV, Allen RH, Stabler SP, Ash JA, Strupp BJ, Stover PJ, Caudill MA. Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration. J Nutr. 2013 Jan; 143(1):41-5. PMID: 23190757; PMCID: PMC3521460.
    27. Yi S, Seth EC, Men YJ, Stabler SP, Allen RH, Alvarez-Cohen L, Taga ME. Versatility in corrinoid salvaging and remodeling pathways supports corrinoid-dependent metabolism in Dehalococcoides mccartyi. Appl Environ Microbiol. 2012 Nov; 78(21):7745-52. PMID: 22923412; PMCID: PMC3485714.
    28. Maclean KN, Greiner LS, Evans JR, Sood SK, Lhotak S, Markham NE, Stabler SP, Allen RH, Austin RC, Balasubramaniam V, Jiang H. Cystathionine protects against endoplasmic reticulum stress-induced lipid accumulation, tissue injury, and apoptotic cell death. J Biol Chem. 2012 Sep 14; 287(38):31994-2005. PMID: 22854956; PMCID: PMC3442531.
    29. Flores KG, Stidley CA, Mackey AJ, Picchi MA, Stabler SP, Siegfried JM, Byers T, Berwick M, Belinsky SA, Leng S. Sex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in the lung epithelium of smokers. Carcinogenesis. 2012 Aug; 33(8):1542-7. PMID: 22665368; PMCID: PMC3499054.
    30. Jiang H, Stabler SP, Allen RH, Maclean KN. Altered expression of apoA-I, apoA-IV and PON-1 activity in CBS deficient homocystinuria in the presence and absence of treatment: possible implications for cardiovascular outcomes. Mol Genet Metab. 2012 Sep; 107(1-2):55-65. PMID: 22633282.
      View in: PubMed
    31. Yan J, Jiang X, West AA, Perry CA, Malysheva OV, Devapatla S, Pressman E, Vermeylen F, Stabler SP, Allen RH, Caudill MA. Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans. Am J Clin Nutr. 2012 May; 95(5):1060-71. PMID: 22418088.
      View in: PubMed
    32. Beaudin AE, Perry CA, Stabler SP, Allen RH, Stover PJ. Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. Am J Clin Nutr. 2012 Apr; 95(4):882-91. PMID: 22378735; PMCID: PMC3302363.
    33. Xiao S, Tang YS, Khan RA, Zhang Y, Kusumanchi P, Stabler SP, Jayaram HN, Antony AC. Influence of physiologic folate deficiency on human papillomavirus type 16 (HPV16)-harboring human keratinocytes in vitro and in vivo. J Biol Chem. 2012 Apr 06; 287(15):12559-77. PMID: 22351779; PMCID: PMC3321005.
    34. Maclean KN, Jiang H, Greiner LS, Allen RH, Stabler SP. Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk. Mol Genet Metab. 2012 Mar; 105(3):395-403. PMID: 22192524.
      View in: PubMed
    35. Mudd SH, Wagner C, Luka Z, Stabler SP, Allen RH, Schroer R, Wood T, Wang J, Wong LJ. Two patients with hepatic mtDNA depletion syndromes and marked elevations of S-adenosylmethionine and methionine. Mol Genet Metab. 2012 Feb; 105(2):228-36. PMID: 22137549; PMCID: PMC3264801.
    36. MacFarlane AJ, Anderson DD, Flodby P, Perry CA, Allen RH, Stabler SP, Stover PJ. Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA. J Biol Chem. 2011 Dec 23; 286(51):44015-22. PMID: 22057276; PMCID: PMC3243516.
    37. Hausman DB, Johnson MA, Davey A, Woodard JL, Poon LW, Allen RH, Stabler SP. The oldest old: red blood cell and plasma folate in African American and white octogenarians and centenarians in Georgia. J Nutr Health Aging. 2011 Nov; 15(9):744-50. PMID: 22089222; PMCID: PMC3233985.
    38. Medici V, Virata MC, Peerson JM, Stabler SP, French SW, Gregory JF, Albanese A, Bowlus CL, Devaraj S, Panacek EA, Richards JR, Halsted CH. S-adenosyl-L-methionine treatment for alcoholic liver disease: a double-blinded, randomized, placebo-controlled trial. Alcohol Clin Exp Res. 2011 Nov; 35(11):1960-5. PMID: 22044287; PMCID: PMC3315189.
    39. Haslam A, Hausman DB, Johnson MA, Davey A, Poon LW, Allen RH, Stabler SP. Prevalence and predictors of anemia in a population-based study of octogenarians and centenarians in Georgia. J Gerontol A Biol Sci Med Sci. 2012 Jan; 67(1):100-6. PMID: 21896502; PMCID: PMC3260487.
    40. Stabler S, Koyama T, Zhao Z, Martinez-Ferrer M, Allen RH, Luka Z, Loukachevitch LV, Clark PE, Wagner C, Bhowmick NA. Serum methionine metabolites are risk factors for metastatic prostate cancer progression. PLoS One. 2011; 6(8):e22486. PMID: 21853037; PMCID: PMC3154200.
    41. Benight NM, Stoll B, Chacko S, da Silva VR, Marini JC, Gregory JF, Stabler SP, Burrin DG. B-vitamin deficiency is protective against DSS-induced colitis in mice. Am J Physiol Gastrointest Liver Physiol. 2011 Aug; 301(2):G249-59. PMID: 21596995; PMCID: PMC3154603.
    42. Yetley EA, Pfeiffer CM, Phinney KW, Bailey RL, Blackmore S, Bock JL, Brody LC, Carmel R, Curtin LR, Durazo-Arvizu RA, Eckfeldt JH, Green R, Gregory JF, Hoofnagle AN, Jacobsen DW, Jacques PF, Lacher DA, Molloy AM, Massaro J, Mills JL, Nexo E, Rader JI, Selhub J, Sempos C, Shane B, Stabler S, Stover P, Tamura T, Tedstone A, Thorpe SJ, Coates PM, Johnson CL, Picciano MF. Biomarkers of vitamin B-12 status in NHANES: a roundtable summary. Am J Clin Nutr. 2011 Jul; 94(1):313S-321S. PMID: 21593512; PMCID: PMC3127527.
    43. Yetley EA, Pfeiffer CM, Phinney KW, Fazili Z, Lacher DA, Bailey RL, Blackmore S, Bock JL, Brody LC, Carmel R, Curtin LR, Durazo-Arvizu RA, Eckfeldt JH, Green R, Gregory JF, Hoofnagle AN, Jacobsen DW, Jacques PF, Molloy AM, Massaro J, Mills JL, Nexo E, Rader JI, Selhub J, Sempos C, Shane B, Stabler S, Stover P, Tamura T, Tedstone A, Thorpe SJ, Coates PM, Johnson CL, Picciano MF. Biomarkers of folate status in NHANES: a roundtable summary. Am J Clin Nutr. 2011 Jul; 94(1):303S-312S. PMID: 21593502; PMCID: PMC3127517.
    44. Keating AK, Freehauf C, Jiang H, Brodsky GL, Stabler SP, Allen RH, Graham DK, Thomas JA, Van Hove JL, Maclean KN. Constitutive induction of pro-inflammatory and chemotactic cytokines in cystathionine beta-synthase deficient homocystinuria. Mol Genet Metab. 2011 Aug; 103(4):330-7. PMID: 21601502; PMCID: PMC4141465.
    45. Beaudin AE, Abarinov EV, Noden DM, Perry CA, Chu S, Stabler SP, Allen RH, Stover PJ. Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice. Am J Clin Nutr. 2011 Apr; 93(4):789-98. PMID: 21346092; PMCID: PMC3057548.
    46. Yan J, Wang W, Gregory JF, Malysheva O, Brenna JT, Stabler SP, Allen RH, Caudill MA. MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline. Am J Clin Nutr. 2011 Feb; 93(2):348-55. PMID: 21123458; PMCID: PMC3021427.
    47. Grubbs R, Vugrek O, Deisch J, Wagner C, Stabler S, Allen R, Baric I, Rados M, Mudd SH. S-adenosylhomocysteine hydrolase deficiency: two siblings with fetal hydrops and fatal outcomes. J Inherit Metab Dis. 2010 Dec; 33(6):705-13. PMID: 20852937.
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    48. Fernández-Irigoyen J, Santamaría E, Chien YH, Hwu WL, Korman SH, Faghfoury H, Schulze A, Hoganson GE, Stabler SP, Allen RH, Wagner C, Mudd SH, Corrales FJ. Enzymatic activity of methionine adenosyltransferase variants identified in patients with persistent hypermethioninemia. Mol Genet Metab. 2010 Oct-Nov; 101(2-3):172-7. PMID: 20675163.
      View in: PubMed
    49. Maclean KN, Sikora J, Kožich V, Jiang H, Greiner LS, Kraus E, Krijt J, Overdier KH, Collard R, Brodsky GL, Meltesen L, Crnic LS, Allen RH, Stabler SP, Elleder M, Rozen R, Patterson D, Kraus JP. A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment. Mol Genet Metab. 2010 Oct-Nov; 101(2-3):153-62. PMID: 20638879; PMCID: PMC2954364.
    50. Maclean KN, Sikora J, Kožich V, Jiang H, Greiner LS, Kraus E, Krijt J, Crnic LS, Allen RH, Stabler SP, Elleder M, Kraus JP. Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment. Mol Genet Metab. 2010 Oct-Nov; 101(2-3):163-71. PMID: 20638882; PMCID: PMC2954358.
    51. Medici V, Peerson JM, Stabler SP, French SW, Gregory JF, Virata MC, Albanese A, Bowlus CL, Devaraj S, Panacek EA, Rahim N, Richards JR, Rossaro L, Halsted CH. Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease. J Hepatol. 2010 Sep; 53(3):551-7. PMID: 20561703; PMCID: PMC2923260.
    52. Johnson MA, Hausman DB, Davey A, Poon LW, Allen RH, Stabler SP. Vitamin B12 deficiency in African American and white octogenarians and centenarians in Georgia. J Nutr Health Aging. 2010 May; 14(5):339-45. PMID: 20424799; PMCID: PMC2978918.
    53. Bor MV, von Castel-Roberts KM, Kauwell GP, Stabler SP, Allen RH, Maneval DR, Bailey LB, Nexo E. Daily intake of 4 to 7 microg dietary vitamin B-12 is associated with steady concentrations of vitamin B-12-related biomarkers in a healthy young population. Am J Clin Nutr. 2010 Mar; 91(3):571-7. PMID: 20071646.
      View in: PubMed
    54. Matteini AM, Walston JD, Bandeen-Roche K, Arking DE, Allen RH, Fried LP, Chakravarti A, Stabler SP, Fallin MD. Transcobalamin-II variants, decreased vitamin B12 availability and increased risk of frailty. J Nutr Health Aging. 2010 Jan; 14(1):73-7. PMID: 20082058; PMCID: PMC3042247.
    55. Guerra-Shinohara EM, Pereira PM, Kubota AM, Silva TA, Reis JL, Miyashita GS, D'Almeida V, Allen RH, Stabler SP. Increased MMA concentration and body mass index are associated with spontaneous abortion in Brazilian women: a pilot study. Clin Chim Acta. 2010 Mar; 411(5-6):423-7. PMID: 20036223.
      View in: PubMed
    56. Girard CL, Santschi DE, Stabler SP, Allen RH. Apparent ruminal synthesis and intestinal disappearance of vitamin B12 and its analogs in dairy cows. J Dairy Sci. 2009 Sep; 92(9):4524-9. PMID: 19700714.
      View in: PubMed
    57. Stabler SP, Sekhar J, Allen RH, O'Neill HC, White CW. Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine. Free Radic Biol Med. 2009 Oct 15; 47(8):1147-53. PMID: 19616616; PMCID: PMC2782850.
    58. Vanderjagt DJ, Ujah IA, Patel A, Kellywood J, Crossey MJ, Allen RH, Stabler SP, Obande OS, Glew RH. Subclinical vitamin B12 deficiency in pregnant women attending an antenatal clinic in Nigeria. J Obstet Gynaecol. 2009 May; 29(4):288-95. PMID: 19835494.
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    59. Kraus JP, Hasek J, Kozich V, Collard R, Venezia S, Janosíková B, Wang J, Stabler SP, Allen RH, Jakobs C, Finn CT, Chien YH, Hwu WL, Hegele RA, Mudd SH. Cystathionine gamma-lyase: Clinical, metabolic, genetic, and structural studies. Mol Genet Metab. 2009 Aug; 97(4):250-9. PMID: 19428278; PMCID: PMC2752209.
    60. Girard CL, Berthiaume R, Stabler SP, Allen RH. Identification of cobalamin and cobalamin analogues along the gastrointestinal tract of dairy cows. Arch Anim Nutr. 2009; 63(5):379-88. PMID: 26967796.
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    61. MacFarlane AJ, Perry CA, Girnary HH, Gao D, Allen RH, Stabler SP, Shane B, Stover PJ. Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. J Biol Chem. 2009 Jan 16; 284(3):1533-9. PMID: 19033438; PMCID: PMC2615521.
    62. Panayiotidis MI, Stabler SP, Allen RH, Pappa A, White CW. Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells. Mutat Res. 2009 Mar 31; 674(1-2):23-30. PMID: 19010443.
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    63. Lopreato FR, Stabler SP, Carvalho FR, Hirata RD, Hirata MH, Robi DL, Sampaio-Neto LF, Allen RH, Guerra-Shinohara EM. Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates. Clin Chim Acta. 2008 Dec; 398(1-2):134-9. PMID: 18823966.
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    64. MacFarlane AJ, Liu X, Perry CA, Flodby P, Allen RH, Stabler SP, Stover PJ. Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice. J Biol Chem. 2008 Sep 19; 283(38):25846-53. PMID: 18644786; PMCID: PMC2533799.
    65. Allen RH, Stabler SP. Identification and quantitation of cobalamin and cobalamin analogues in human feces. Am J Clin Nutr. 2008 May; 87(5):1324-35. PMID: 18469256; PMCID: PMC2900183.
    66. Matteini AM, Walston JD, Fallin MD, Bandeen-Roche K, Kao WH, Semba RD, Allen RH, Guralnik J, Fried LP, Stabler SP. Markers of B-vitamin deficiency and frailty in older women. J Nutr Health Aging. 2008 May; 12(5):303-8. PMID: 18443711; PMCID: PMC2739594.
    67. Gibson RS, Abebe Y, Stabler S, Allen RH, Westcott JE, Stoecker BJ, Krebs NF, Hambidge KM. Zinc, gravida, infection, and iron, but not vitamin B-12 or folate status, predict hemoglobin during pregnancy in Southern Ethiopia. J Nutr. 2008 Mar; 138(3):581-6. PMID: 18287370; PMCID: PMC2440679.
    68. Barbosa PR, Stabler SP, Trentin R, Carvalho FR, Luchessi AD, Hirata RD, Hirata MH, Allen RH, Guerra-Shinohara EM. Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women. Clin Chim Acta. 2008 Feb; 388(1-2):139-47. PMID: 18023275.
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    69. Chandler RJ, Sloan J, Fu H, Tsai M, Stabler S, Allen R, Kaestner KH, Kazazian HH, Venditti CP. Metabolic phenotype of methylmalonic acidemia in mice and humans: the role of skeletal muscle. BMC Med Genet. 2007 Oct 15; 8:64. PMID: 17937813; PMCID: PMC2140053.
    70. Sekhar J, Stabler SP. Life-threatening megaloblastic pancytopenia with normal mean cell volume: Case series. Eur J Intern Med. 2007 Nov; 18(7):548-50. PMID: 17967337; PMCID: PMC2735269.
    71. Vitvitsky V, Prudova A, Stabler S, Dayal S, Lentz SR, Banerjee R. Testosterone regulation of renal cystathionine beta-synthase: implications for sex-dependent differences in plasma homocysteine levels. Am J Physiol Renal Physiol. 2007 Aug; 293(2):F594-600. PMID: 17537983.
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    72. Barbosa PR, Stabler SP, Machado AL, Braga RC, Hirata RD, Hirata MH, Sampaio-Neto LF, Allen RH, Guerra-Shinohara EM. Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women. Eur J Clin Nutr. 2008 Aug; 62(8):1010-21. PMID: 17522601.
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    73. Fischer LM, daCosta KA, Kwock L, Stewart PW, Lu TS, Stabler SP, Allen RH, Zeisel SH. Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr. 2007 May; 85(5):1275-85. PMID: 17490963; PMCID: PMC2435503.
    74. Strauss KA, Morton DH, Puffenberger EG, Hendrickson C, Robinson DL, Wagner C, Stabler SP, Allen RH, Chwatko G, Jakubowski H, Niculescu MD, Mudd SH. Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency. Mol Genet Metab. 2007 Jun; 91(2):165-75. PMID: 17409006.
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    75. Guerra-Shinohara EM, Morita OE, Pagliusi RA, Blaia-d'Avila VL, Allen RH, Stabler SP. Elevated serum S-adenosylhomocysteine in cobalamin-deficient megaloblastic anemia. Metabolism. 2007 Mar; 56(3):339-47. PMID: 17292722; PMCID: PMC1974902.
    76. Mudd SH, Brosnan JT, Brosnan ME, Jacobs RL, Stabler SP, Allen RH, Vance DE, Wagner C. Methyl balance and transmethylation fluxes in humans. Am J Clin Nutr. 2007 Jan; 85(1):19-25. PMID: 17209172.
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    77. Moat SJ, Madhavan A, Taylor SY, Payne N, Allen RH, Stabler SP, Goodfellow J, McDowell IF, Lewis MJ, Lang D. High- but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest. 2006 Dec; 36(12):850-9. PMID: 17087779.
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    79. Chandler RJ, Aswani V, Tsai MS, Falk M, Wehrli N, Stabler S, Allen R, Sedensky M, Kazazian HH, Venditti CP. Propionyl-CoA and adenosylcobalamin metabolism in Caenorhabditis elegans: evidence for a role of methylmalonyl-CoA epimerase in intermediary metabolism. Mol Genet Metab. 2006 Sep-Oct; 89(1-2):64-73. PMID: 16843692; PMCID: PMC2761207.
    80. Walter S, Stabler S, Lefkowitz JB. Fibrinogen Denver: a dysfibrinogenemia associated with an abnormal Reptilase time and significant bleeding. Haemophilia. 2006 Jul; 12(4):393-7. PMID: 16834739.
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    81. Buist NR, Glenn B, Vugrek O, Wagner C, Stabler S, Allen RH, Pogribny I, Schulze A, Zeisel SH, Baric I, Mudd SH. S-adenosylhomocysteine hydrolase deficiency in a 26-year-old man. J Inherit Metab Dis. 2006 Aug; 29(4):538-45. PMID: 16736098; PMCID: PMC2430673.
    82. Park S, Johnson MA, Shea-Miller K, De Chicchis AR, Allen RH, Stabler SP. Age-related hearing loss, methylmalonic acid, and vitamin B12 status in older adults. J Nutr Elder. 2006; 25(3-4):105-20. PMID: 18032219.
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    83. Panayiotidis MI, Stabler SP, Ahmad A, Pappa A, Legros LH, Hernandez-Saavedra D, Schneider BK, Allen RH, Vasiliou V, McCord JM, Kotb M, White CW. Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia. Free Radic Biol Med. 2006 Jan 15; 40(2):348-58. PMID: 16413417.
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    84. Robertson J, Iemolo F, Stabler SP, Allen RH, Spence JD. Vitamin B12, homocysteine and carotid plaque in the era of folic acid fortification of enriched cereal grain products. CMAJ. 2005 Jun 07; 172(12):1569-73. PMID: 15939916; PMCID: PMC558171.
    85. Wright CB, Paik MC, Brown TR, Stabler SP, Allen RH, Sacco RL, DeCarli C. Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study. Stroke. 2005 Jun; 36(6):1207-11. PMID: 15879345; PMCID: PMC1352322.
    86. Doshi S, McDowell I, Goodfellow J, Stabler S, Boger R, Allen R, Newcombe R, Lewis M, Moat S. Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia. Metabolism. 2005 Mar; 54(3):351-60. PMID: 15736113.
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    87. Baric I, Cuk M, Fumic K, Vugrek O, Allen RH, Glenn B, Maradin M, Pazanin L, Pogribny I, Rados M, Sarnavka V, Schulze A, Stabler S, Wagner C, Zeisel SH, Mudd SH. S-Adenosylhomocysteine hydrolase deficiency: a second patient, the younger brother of the index patient, and outcomes during therapy. J Inherit Metab Dis. 2005; 28(6):885-902. PMID: 16435181; PMCID: PMC2441944.
    88. Xiao S, Hansen DK, Horsley ET, Tang YS, Khan RA, Stabler SP, Jayaram HN, Antony AC. Maternal folate deficiency results in selective upregulation of folate receptors and heterogeneous nuclear ribonucleoprotein-E1 associated with multiple subtle aberrations in fetal tissues. Birth Defects Res A Clin Mol Teratol. 2005 Jan; 73(1):6-28. PMID: 15641086.
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    89. Lewis MS, Miller LS, Johnson MA, Dolce EB, Allen RH, Stabler SP. Elevated methylmalonic acid is related to cognitive impairement in older adults enrolled in an elderly nutrition program. J Nutr Elder. 2005; 24(3):47-65. PMID: 15911524.
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    90. Guerra-Shinohara EM, Morita OE, Peres S, Pagliusi RA, Sampaio Neto LF, D'Almeida V, Irazusta SP, Allen RH, Stabler SP. Low ratio of S-adenosylmethionine to S-adenosylhomocysteine is associated with vitamin deficiency in Brazilian pregnant women and newborns. Am J Clin Nutr. 2004 Nov; 80(5):1312-21. PMID: 15531681.
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    91. Sacco RL, Anand K, Lee HS, Boden-Albala B, Stabler S, Allen R, Paik MC. Homocysteine and the risk of ischemic stroke in a triethnic cohort: the NOrthern MAnhattan Study. Stroke. 2004 Oct; 35(10):2263-9. PMID: 15345803.
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    92. Wright CB, Lee HS, Paik MC, Stabler SP, Allen RH, Sacco RL. Total homocysteine and cognition in a tri-ethnic cohort: the Northern Manhattan Study. Neurology. 2004 Jul 27; 63(2):254-60. PMID: 15277617; PMCID: PMC1352321.
    93. Baric I, Fumic K, Glenn B, Cuk M, Schulze A, Finkelstein JD, James SJ, Mejaski-Bosnjak V, Pazanin L, Pogribny IP, Rados M, Sarnavka V, Scukanec-Spoljar M, Allen RH, Stabler S, Uzelac L, Vugrek O, Wagner C, Zeisel S, Mudd SH. S-adenosylhomocysteine hydrolase deficiency in a human: a genetic disorder of methionine metabolism. Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12):4234-9. PMID: 15024124; PMCID: PMC384724.
    94. Vitvitsky V, Dayal S, Stabler S, Zhou Y, Wang H, Lentz SR, Banerjee R. Perturbations in homocysteine-linked redox homeostasis in a murine model for hyperhomocysteinemia. Am J Physiol Regul Integr Comp Physiol. 2004 Jul; 287(1):R39-46. PMID: 15016621.
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    95. Panayiotidis MI, Stabler SP, Allen RH, Ahmad A, White CW. Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells. Chem Biol Interact. 2004 Jan 15; 147(1):87-97. PMID: 14726155.
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    96. Antony A, Tang YS, Khan RA, Biju MP, Xiao X, Li QJ, Sun XL, Jayaram HN, Stabler SP. Translational upregulation of folate receptors is mediated by homocysteine via RNA-heterogeneous nuclear ribonucleoprotein E1 interactions. J Clin Invest. 2004 Jan; 113(2):285-301. PMID: 14722620; PMCID: PMC310746.
    97. Stabler SP, Allen RH. Vitamin B12 deficiency as a worldwide problem. Annu Rev Nutr. 2004; 24:299-326. PMID: 15189123.
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    98. Stabler SP, Allen RH. Quantification of serum and urinary S-adenosylmethionine and S-adenosylhomocysteine by stable-isotope-dilution liquid chromatography-mass spectrometry. Clin Chem. 2004 Feb; 50(2):365-72. PMID: 14656903.
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    99. Stabler SP. Vitamins, homocysteine, and cognition. Am J Clin Nutr. 2003 Sep; 78(3):359-60. PMID: 12936915.
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    100. Harvey Mudd S, Braverman N, Pomper M, Tezcan K, Kronick J, Jayakar P, Garganta C, Ampola MG, Levy HL, McCandless SE, Wiltse H, Stabler SP, Allen RH, Wagner C, Borschel MW. Infantile hypermethioninemia and hyperhomocysteinemia due to high methionine intake: a diagnostic trap. Mol Genet Metab. 2003 May; 79(1):6-16. PMID: 12765841.
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    101. Stabler SP, Mudd SH. Population screening. N Engl J Med. 2003 Apr 17; 348(16):1604-5; author reply 1604-5. PMID: 12700387.
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    102. Hoots WK, Leissinger C, Stabler S, Schwartz BA, White G, Dasani H, Massion C, Negrier C, Schindel F, Schulman S. Continuous intravenous infusion of a plasma-derived factor IX concentrate (Mononine) in haemophilia B. Haemophilia. 2003 Mar; 9(2):164-72. PMID: 12614367.
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    103. Johnson MA, Hawthorne NA, Brackett WR, Fischer JG, Gunter EW, Allen RH, Stabler SP. Hyperhomocysteinemia and vitamin B-12 deficiency in elderly using Title IIIc nutrition services. Am J Clin Nutr. 2003 Jan; 77(1):211-20. PMID: 12499344.
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    104. Augoustides-Savvopoulou P, Luka Z, Karyda S, Stabler SP, Allen RH, Patsiaoura K, Wagner C, Mudd SH. Glycine N -methyltransferase deficiency: a new patient with a novel mutation. J Inherit Metab Dis. 2003; 26(8):745-59. PMID: 14739680.
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    105. Orendác M, Zeman J, Stabler SP, Allen RH, Kraus JP, Bodamer O, Stöckler-Ipsiroglu S, Kvasnicka J, Kozich V. Homocystinuria due to cystathionine beta-synthase deficiency: novel biochemical findings and treatment efficacy. J Inherit Metab Dis. 2003; 26(8):761-73. PMID: 14739681.
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    106. Mudd SH, Tangerman A, Stabler SP, Allen RH, Wagner C, Zeisel SH, Levy HL. Maternal methionine adenosyltransferase I/III deficiency: reproductive outcomes in a woman with four pregnancies. J Inherit Metab Dis. 2003; 26(5):443-58. PMID: 14518826.
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    107. Rajan S, Wallace JI, Brodkin KI, Beresford SA, Allen RH, Stabler SP. Response of elevated methylmalonic acid to three dose levels of oral cobalamin in older adults. J Am Geriatr Soc. 2002 Nov; 50(11):1789-95. PMID: 12410896.
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    108. Stabler SP, Steegborn C, Wahl MC, Oliveriusova J, Kraus JP, Allen RH, Wagner C, Mudd SH. Elevated plasma total homocysteine in severe methionine adenosyltransferase I/III deficiency. Metabolism. 2002 Aug; 51(8):981-8. PMID: 12145770.
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    109. Maclean KN, Gaustadnes M, Oliveriusová J, Janosík M, Kraus E, Kozich V, Kery V, Skovby F, Rüdiger N, Ingerslev J, Stabler SP, Allen RH, Kraus JP. High homocysteine and thrombosis without connective tissue disorders are associated with a novel class of cystathionine beta-synthase (CBS) mutations. Hum Mutat. 2002 Jun; 19(6):641-55. PMID: 12007221.
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    110. Cottington EM, LaMantia C, Stabler SP, Allen RH, Tangerman A, Wagner C, Zeisel SH, Mudd SH. Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol. 2002 Jun 01; 22(6):1046-50. PMID: 12067919.
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    111. Niyikiza C, Baker SD, Seitz DE, Walling JM, Nelson K, Rusthoven JJ, Stabler SP, Paoletti P, Calvert AH, Allen RH. Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy. Mol Cancer Ther. 2002 May; 1(7):545-52. PMID: 12479273.
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    112. Rajan S, Wallace JI, Beresford SA, Brodkin KI, Allen RA, Stabler SP. Screening for cobalamin deficiency in geriatric outpatients: prevalence and influence of synthetic cobalamin intake. J Am Geriatr Soc. 2002 Apr; 50(4):624-30. PMID: 11982661.
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    113. Yaghmai R, Kashani AH, Geraghty MT, Okoh J, Pomper M, Tangerman A, Wagner C, Stabler SP, Allen RH, Mudd SH, Braverman N. Progressive cerebral edema associated with high methionine levels and betaine therapy in a patient with cystathionine beta-synthase (CBS) deficiency. Am J Med Genet. 2002 Feb 15; 108(1):57-63. PMID: 11857551.
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    114. Look MP, Riezler R, Berthold HK, Stabler SP, Schliefer K, Allen RH, Sauerbruch T, Rockstroh JK. Decrease of elevated N,N-dimethylglycine and N-methylglycine in human immunodeficiency virus infection during short-term highly active antiretroviral therapy. Metabolism. 2001 Nov; 50(11):1275-81. PMID: 11699044.
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    115. Mudd SH, Cerone R, Schiaffino MC, Fantasia AR, Minniti G, Caruso U, Lorini R, Watkins D, Matiaszuk N, Rosenblatt DS, Schwahn B, Rozen R, LeGros L, Kotb M, Capdevila A, Luka Z, Finkelstein JD, Tangerman A, Stabler SP, Allen RH, Wagner C. Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia. J Inherit Metab Dis. 2001 Aug; 24(4):448-64. PMID: 11596649.
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    116. Cohen JA, Jeffers BW, Stabler S, Schrier RW, Estascio R. Increasing homocysteine levels and diabetic autonomic neuropathy. Auton Neurosci. 2001 Mar 23; 87(2-3):268-73. PMID: 11476288.
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    117. Koehler KM, Baumgartner RN, Garry PJ, Allen RH, Stabler SP, Rimm EB. Association of folate intake and serum homocysteine in elderly persons according to vitamin supplementation and alcohol use. Am J Clin Nutr. 2001 Mar; 73(3):628-37. PMID: 11237942.
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    118. Stabler SP, Morton RL, Winski SL, Allen RH, White CW. Effects of parenteral cysteine and glutathione feeding in a baboon model of severe prematurity. Am J Clin Nutr. 2000 Dec; 72(6):1548-57. PMID: 11101485.
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    119. Look MP, Altfeld M, Kreuzer KA, Riezler R, Stabler SP, Allen RH, Sauerbruch T, Rockstroh JK. Parallel decrease in neurotoxin quinolinic acid and soluble tumor necrosis factor receptor p75 in serum during highly active antiretroviral therapy of HIV type 1 disease. AIDS Res Hum Retroviruses. 2000 Sep 01; 16(13):1215-21. PMID: 10957719.
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    120. Look MP, Riezler R, Reichel C, Brensing KA, Rockstroh JK, Stabler SP, Spengler U, Berthold HK, Sauerbruch T. Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at the level of gamma-cystathionase? Scand J Gastroenterol. 2000 Aug; 35(8):866-72. PMID: 10994627.
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    121. Sponne IE, Gaire D, Stabler SP, Droesch S, Barbé FM, Allen RH, Lambert DA, Nicolas JP. Inhibition of vitamin B12 metabolism by OH-cobalamin c-lactam in rat oligodendrocytes in culture: a model for studying neuropathy due to vitamin B12 deficiency. Neurosci Lett. 2000 Jul 21; 288(3):191-4. PMID: 10889340.
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    122. Mudd SH, Finkelstein JD, Refsum H, Ueland PM, Malinow MR, Lentz SR, Jacobsen DW, Brattström L, Wilcken B, Wilcken DE, Blom HJ, Stabler SP, Allen RH, Selhub J, Rosenberg IH. Homocysteine and its disulfide derivatives: a suggested consensus terminology. Arterioscler Thromb Vasc Biol. 2000 Jul; 20(7):1704-6. PMID: 10894806.
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    123. Savage DG, Ogundipe A, Allen RH, Stabler SP, Lindenbaum J. Etiology and diagnostic evaluation of macrocytosis. Am J Med Sci. 2000 Jun; 319(6):343-52. PMID: 10875288.
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    124. Penninx BW, Guralnik JM, Ferrucci L, Fried LP, Allen RH, Stabler SP. Vitamin B(12) deficiency and depression in physically disabled older women: epidemiologic evidence from the Women's Health and Aging Study. Am J Psychiatry. 2000 May; 157(5):715-21. PMID: 10784463.
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    125. Stabler SP. Using homocysteine and related metabolites to diagnose vitamin deficiency states. Biofactors. 2000; 11(1-2):51-2. PMID: 10705959.
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    126. Stabler SP, Allen RH, Fried LP, Pahor M, Kittner SJ, Penninx BW, Guralnik JM. Racial differences in prevalence of cobalamin and folate deficiencies in disabled elderly women. Am J Clin Nutr. 1999 Nov; 70(5):911-9. PMID: 10539754.
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    127. Stabler SP, Estacio R, Jeffers BW, Cohen JA, Allen RH, Schrier RW. Total homocysteine is associated with nephropathy in non-insulin-dependent diabetes mellitus. Metabolism. 1999 Sep; 48(9):1096-101. PMID: 10484047.
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    128. Savage DG, Allen RH, Gangaidzo IT, Levy LM, Gwanzura C, Moyo A, Mudenge B, Kiire C, Mukiibi J, Stabler SP, Lindenbaum J. Pancytopenia in Zimbabwe. Am J Med Sci. 1999 Jan; 317(1):22-32. PMID: 9892268.
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    129. Kuzminski AM, Del Giacco EJ, Allen RH, Stabler SP. Oral cobalamin therapy in patients who absorb it normally. Blood. 1998 Dec 15; 92(12):4879-80. PMID: 9988549.
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    130. Stabler SP. Vitamin B12 deficiency in older people: improving diagnosis and preventing disability. J Am Geriatr Soc. 1998 Oct; 46(10):1317-9. PMID: 9777920.
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    131. Kuzminski AM, Del Giacco EJ, Allen RH, Stabler SP, Lindenbaum J. Effective treatment of cobalamin deficiency with oral cobalamin. Blood. 1998 Aug 15; 92(4):1191-8. PMID: 9694707.
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    132. Allen RH, Stabler SP, Lindenbaum J. Relevance of vitamins, homocysteine and other metabolites in neuropsychiatric disorders. Eur J Pediatr. 1998 Apr; 157 Suppl 2:S122-6. PMID: 9587039.
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    133. Stabler SP, Lindenbaum J, Allen RH. Vitamin B-12 deficiency in the elderly: current dilemmas. Am J Clin Nutr. 1997 Oct; 66(4):741-9. PMID: 9322547.
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    134. Verhoef P, Hennekens CH, Allen RH, Stabler SP, Willett WC, Stampfer MJ. Plasma total homocysteine and risk of angina pectoris with subsequent coronary artery bypass surgery. Am J Cardiol. 1997 Mar 15; 79(6):799-801. PMID: 9070565.
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    135. Zubenko GS, Henderson R, Stiffler JS, Stabler S, Rosen J, Kaplan BB. Association of the APOE epsilon 4 allele with clinical subtypes of late life depression. Biol Psychiatry. 1996 Nov 15; 40(10):1008-16. PMID: 8915560.
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    136. Ragni MV, Belle SH, Jaffe R, Locker J, Duerstein SL, Bass DC, Addiego JE, Aledort LM, Barron LE, Brettler DB, Buchanan GR, Gill JC, Ewenstein BM, Green D, Hilgartner MW, Hoots WK, Kisker CT, Lovrien EW, Rutherford CJ, Sanders NL, Smith KJ, Stabler SP, Swindells S, White GC, Kingsley LA. AIDS-associated non-Hodgkin's lymphomas as primary and secondary AIDS diagnoses in hemophiliacs. Hemophilia Malignancy Study Group. J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Sep; 13(1):78-86. PMID: 8797689.
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    137. Koehler KM, Romero LJ, Stauber PM, Pareo-Tubbeh SL, Liang HC, Baumgartner RN, Garry PJ, Allen RH, Stabler SP. Vitamin supplementation and other variables affecting serum homocysteine and methylmalonic acid concentrations in elderly men and women. J Am Coll Nutr. 1996 Aug; 15(4):364-76. PMID: 8829092.
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    138. Ubbink JB, van der Merwe A, Delport R, Allen RH, Stabler SP, Riezler R, Vermaak WJ. The effect of a subnormal vitamin B-6 status on homocysteine metabolism. J Clin Invest. 1996 Jul 01; 98(1):177-84. PMID: 8690790; PMCID: PMC507414.
    139. Verhoef P, Stampfer MJ, Buring JE, Gaziano JM, Allen RH, Stabler SP, Reynolds RD, Kok FJ, Hennekens CH, Willett WC. Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate. Am J Epidemiol. 1996 May 01; 143(9):845-59. PMID: 8610698.
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    140. Herzlich BC, Lichstein E, Schulhoff N, Weinstock M, Pagala M, Ravindran K, Namba T, Nieto FJ, Stabler SP, Allen RH, Malinow MR. Relationship among homocyst(e)ine, vitamin B-12 and cardiac disease in the elderly: association between vitamin B-12 deficiency and decreased left ventricular ejection fraction. J Nutr. 1996 Apr; 126(4 Suppl):1249S-53S. PMID: 8642465.
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    141. Stabler SP, Lindenbaum J, Allen RH. The use of homocysteine and other metabolites in the specific diagnosis of vitamin B-12 deficiency. J Nutr. 1996 Apr; 126(4 Suppl):1266S-72S. PMID: 8642468.
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    142. Halsted CH, Villanueva J, Chandler CJ, Stabler SP, Allen RH, Muskhelishvili L, James SJ, Poirier L. Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation. Hepatology. 1996 Mar; 23(3):497-505. PMID: 8617429.
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    143. Sumner AE, Chin MM, Abrahm JL, Berry GT, Gracely EJ, Allen RH, Stabler SP. Elevated methylmalonic acid and total homocysteine levels show high prevalence of vitamin B12 deficiency after gastric surgery. Ann Intern Med. 1996 Mar 01; 124(5):469-76. PMID: 8602704.
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    144. Allen RH, Lindenbaum J, Stabler SP. High prevalence of cobalamin deficiency in the elderly. Trans Am Clin Climatol Assoc. 1996; 107:37-45; discussion 45-7. PMID: 8725558; PMCID: PMC2376575.
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    146. Naurath HJ, Joosten E, Riezler R, Stabler SP, Allen RH, Lindenbaum J. Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. Lancet. 1995 Jul 08; 346(8967):85-9. PMID: 7603218.
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    147. Adams MJ, Khoury MJ, Scanlon KS, Stevenson RE, Knight GJ, Haddow JE, Sylvester GC, Cheek JE, Henry JP, Stabler SP, et al. Elevated midtrimester serum methylmalonic acid levels as a risk factor for neural tube defects. Teratology. 1995 May; 51(5):311-7. PMID: 7482352.
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    148. Lindenbaum J, Healton EB, Savage DG, Brust JC, Garrett TJ, Podell ER, Marcell PD, Stabler SP, Allen RH. Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. 1988. Nutrition. 1995 Mar-Apr; 11(2):181; discussion 180, 182. PMID: 7647490.
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    149. Bostom AG, Shemin D, Nadeau MR, Shih V, Stabler SP, Allen RH, Selhub J. Short term betaine therapy fails to lower elevated fasting total plasma homocysteine concentrations in hemodialysis patients maintained on chronic folic acid supplementation. Atherosclerosis. 1995 Feb; 113(1):129-32. PMID: 7755649.
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    150. White CW, Stabler SP, Allen RH, Moreland S, Rosenberg AA. Plasma cysteine concentrations in infants with respiratory distress. J Pediatr. 1994 Nov; 125(5 Pt 1):769-77. PMID: 7965433.
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    151. Zubenko GS, Stiffler S, Stabler S, Kopp U, Hughes HB, Cohen BM, Moossy J. Association of the apolipoprotein E epsilon 4 allele with clinical subtypes of autopsy-confirmed Alzheimer's disease. Am J Med Genet. 1994 Sep 15; 54(3):199-205. PMID: 7810577.
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    152. Lindenbaum J, Rosenberg IH, Wilson PW, Stabler SP, Allen RH. Prevalence of cobalamin deficiency in the Framingham elderly population. Am J Clin Nutr. 1994 Jul; 60(1):2-11. PMID: 8017332.
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    153. Savage DG, Lindenbaum J, Stabler SP, Allen RH. Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies. Am J Med. 1994 Mar; 96(3):239-46. PMID: 8154512.
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    154. Stabler SP, Jones RT, Head C, Shih DT, Fairbanks VF. Hemoglobin Denver [alpha 2 beta 2(41) (C7) Phe-->Ser]: a low-O2-affinity variant associated with chronic cyanosis and anemia. Mayo Clin Proc. 1994 Mar; 69(3):237-43. PMID: 8133661.
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    155. Allen RH, Stabler SP, Lindenbaum J. Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism. Metabolism. 1993 Nov; 42(11):1448-60. PMID: 7694037.
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    156. Allen RH, Stabler SP, Savage DG, Lindenbaum J. Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency. FASEB J. 1993 Nov; 7(14):1344-53. PMID: 7901104.
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    157. Joosten E, van den Berg A, Riezler R, Naurath HJ, Lindenbaum J, Stabler SP, Allen RH. Metabolic evidence that deficiencies of vitamin B-12 (cobalamin), folate, and vitamin B-6 occur commonly in elderly people. Am J Clin Nutr. 1993 Oct; 58(4):468-76. PMID: 8037789.
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    158. Ueland PM, Refsum H, Stabler SP, Malinow MR, Andersson A, Allen RH. Total homocysteine in plasma or serum: methods and clinical applications. Clin Chem. 1993 Sep; 39(9):1764-79. PMID: 8375046.
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    159. Allen RH, Stabler SP, Savage DG, Lindenbaum J. Elevation of 2-methylcitric acid I and II levels in serum, urine, and cerebrospinal fluid of patients with cobalamin deficiency. Metabolism. 1993 Aug; 42(8):978-88. PMID: 8345822.
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    160. Stabler SP, Lindenbaum J, Savage DG, Allen RH. Elevation of serum cystathionine levels in patients with cobalamin and folate deficiency. Blood. 1993 Jun 15; 81(12):3404-13. PMID: 8507876.
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    161. Kolhouse JF, Stabler SP, Allen RH. Identification and perturbation of mutant human fibroblasts based on measurements of methylmalonic acid and total homocysteine in the culture media. Arch Biochem Biophys. 1993 Jun; 303(2):355-60. PMID: 8099783.
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    162. Ragni MV, Belle SH, Jaffe RA, Duerstein SL, Bass DC, McMillan CW, Lovrien EW, Aledort LM, Kisker CT, Stabler SP, et al. Acquired immunodeficiency syndrome-associated non-Hodgkin's lymphomas and other malignancies in patients with hemophilia. Blood. 1993 Apr 01; 81(7):1889-97. PMID: 8461474.
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    163. Rusakow LS, White CW, Stabler SP. O2-induced changes in lung and storage pool thiols in mice: effect of superoxide dismutase. J Appl Physiol (1985). 1993 Mar; 74(3):989-97. PMID: 8482694.
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    164. Pennypacker LC, Allen RH, Kelly JP, Matthews LM, Grigsby J, Kaye K, Lindenbaum J, Stabler SP. High prevalence of cobalamin deficiency in elderly outpatients. J Am Geriatr Soc. 1992 Dec; 40(12):1197-204. PMID: 1447433.
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    165. Allen RH, Stabler SP, Savage DG, Lindenbaum J. New approaches to the diagnosis of cobalamin (Cbl, vitamin B12) deficiency in neuropsychiatric disorders. J Nutr Sci Vitaminol (Tokyo). 1992; Spec No:130-3. PMID: 1297723.
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    166. Kolhouse JF, Utley C, Stabler SP, Allen RH. Mechanism of conversion of human apo- to holomethionine synthase by various forms of cobalamin. J Biol Chem. 1991 Dec 05; 266(34):23010-5. PMID: 1744096.
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    167. Stabler SP, Allen RH, Barrett RE, Savage DG, Lindenbaum J. Cerebrospinal fluid methylmalonic acid levels in normal subjects and patients with cobalamin deficiency. Neurology. 1991 Oct; 41(10):1627-32. PMID: 1922806.
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    168. Stabler SP, Brass EP, Marcell PD, Allen RH. Inhibition of cobalamin-dependent enzymes by cobalamin analogues in rats. J Clin Invest. 1991 Apr; 87(4):1422-30. PMID: 1672697; PMCID: PMC295189.
    169. Krahenbuhl S, Ray DB, Stabler SP, Allen RH, Brass EP. Increased hepatic mitochondrial capacity in rats with hydroxy-cobalamin[c-lactam]-induced methylmalonic aciduria. J Clin Invest. 1990 Dec; 86(6):2054-61. PMID: 1701451; PMCID: PMC329844.
    170. Stabler SP, Allen RH, Savage DG, Lindenbaum J. Clinical spectrum and diagnosis of cobalamin deficiency. Blood. 1990 Sep 01; 76(5):871-81. PMID: 2393714.
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    171. Allen RH, Stabler SP, Savage DG, Lindenbaum J. Diagnosis of cobalamin deficiency I: usefulness of serum methylmalonic acid and total homocysteine concentrations. Am J Hematol. 1990 Jun; 34(2):90-8. PMID: 2339683.
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    172. Lindenbaum J, Savage DG, Stabler SP, Allen RH. Diagnosis of cobalamin deficiency: II. Relative sensitivities of serum cobalamin, methylmalonic acid, and total homocysteine concentrations. Am J Hematol. 1990 Jun; 34(2):99-107. PMID: 2339684.
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    173. Brass EP, Allen RH, Ruff LJ, Stabler SP. Effect of hydroxycobalamin[c-lactam] on propionate and carnitine metabolism in the rat. Biochem J. 1990 Mar 15; 266(3):809-15. PMID: 2327967; PMCID: PMC1131211.
    174. Brass EP, Tahiliani AG, Allen RH, Stabler SP. Coenzyme A metabolism in vitamin B-12-deficient rats. J Nutr. 1990 Mar; 120(3):290-7. PMID: 2319347.
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    175. Broxson EH, Stork LC, Allen RH, Stabler SP, Kolhouse JF. Changes in plasma methionine and total homocysteine levels in patients receiving methotrexate infusions. Cancer Res. 1989 Nov 01; 49(21):5879-83. PMID: 2790801.
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    176. Brass EP, Stabler SP. Carnitine metabolism in the vitamin B-12-deficient rat. Biochem J. 1988 Oct 01; 255(1):153-9. PMID: 3196310; PMCID: PMC1135203.
    177. Lindenbaum J, Healton EB, Savage DG, Brust JC, Garrett TJ, Podell ER, Marcell PD, Stabler SP, Allen RH. Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med. 1988 Jun 30; 318(26):1720-8. PMID: 3374544.
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    178. Stabler SP, Lindenbaum J, Allen RH. Failure to detect beta-leucine in human blood or leucine 2,3-aminomutase in rat liver using capillary gas chromatography-mass spectrometry. J Biol Chem. 1988 Apr 25; 263(12):5581-8. PMID: 3356699.
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    179. Stabler SP, Marcell PD, Podell ER, Allen RH, Savage DG, Lindenbaum J. Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry. J Clin Invest. 1988 Feb; 81(2):466-74. PMID: 3339129; PMCID: PMC329593.
    180. Stabler SP, Allen RH. DL-methylmalonyl-CoA racemase from rat liver. Methods Enzymol. 1988; 166:400-6. PMID: 3071715.
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    181. Kovachy RJ, Stabler SP, Allen RH. D-methylmalonyl-CoA hydrolase. Methods Enzymol. 1988; 166:393-400. PMID: 3071714.
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    182. Kolhouse JF, Stabler SP, Allen RH. L-methylmalonyl-CoA mutase from human placenta. Methods Enzymol. 1988; 166:407-14. PMID: 2907367.
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    183. Stabler SP, Marcell PD, Podell ER, Allen RH. Quantitation of total homocysteine, total cysteine, and methionine in normal serum and urine using capillary gas chromatography-mass spectrometry. Anal Biochem. 1987 Apr; 162(1):185-96. PMID: 3605587.
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    184. Stabler SP, Marcell PD, Podell ER, Allen RH, Lindenbaum J. Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry. J Clin Invest. 1986 May; 77(5):1606-12. PMID: 3700655; PMCID: PMC424564.
    185. Marcell PD, Stabler SP, Podell ER, Allen RH. Quantitation of methylmalonic acid and other dicarboxylic acids in normal serum and urine using capillary gas chromatography-mass spectrometry. Anal Biochem. 1985 Oct; 150(1):58-66. PMID: 4083484.
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    186. Stabler SP, Marcell PD, Allen RH. Isolation and characterization of DL-methylmalonyl-coenzyme A racemase from rat liver. Arch Biochem Biophys. 1985 Aug 15; 241(1):252-64. PMID: 2862845.
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