 In Situ Nick-End Labeling
"In Situ Nick-End Labeling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.
| Descriptor ID |
D020287
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| MeSH Number(s) |
E05.393.475
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| Concept/Terms |
In Situ Nick-End Labeling- In Situ Nick-End Labeling
- TUNEL
- Nick-End Labeling, In Situ
- In Situ Nick End Labelling
- In Situ Nick End Labeling
- In Situ Nick End-Labelling
- In Situ Nick-End Labelling
- Nick End-Labeling, In Situ
- Nick End Labeling, In Situ
- Nick End-Labelling, In Situ
- Nick End Labelling, In Situ
- Nick-End Labelling, In Situ
- In Situ Nick End-Labeling
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Below are MeSH descriptors whose meaning is more general than "In Situ Nick-End Labeling".
Below are MeSH descriptors whose meaning is more specific than "In Situ Nick-End Labeling".
This graph shows the total number of publications written about "In Situ Nick-End Labeling" by people in this website by year, and whether "In Situ Nick-End Labeling" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 10 | 10 | | 2002 | 1 | 7 | 8 | | 2003 | 0 | 4 | 4 | | 2004 | 0 | 8 | 8 | | 2005 | 0 | 6 | 6 | | 2006 | 0 | 6 | 6 | | 2007 | 0 | 10 | 10 | | 2008 | 0 | 2 | 2 | | 2009 | 0 | 4 | 4 | | 2010 | 0 | 10 | 10 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 3 | 3 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 2 | 2 | | 2015 | 0 | 3 | 3 | | 2016 | 0 | 2 | 2 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "In Situ Nick-End Labeling" by people in Profiles.
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Gange WS, Qiao JB, Park PJ, McDonnell JF, Tan Z, Perlman JI, Bu P. Protection of Retinal Function by Nucleoside Reverse Transcriptase Inhibitors Following Retinal Ischemia/Reperfusion Injury. J Ocul Pharmacol Ther. 2021 10; 37(8):485-491.
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Curtis BJ, Shults JA, Boe DM, Ramirez L, Kovacs EJ. Mesenchymal stem cell treatment attenuates liver and lung inflammation after ethanol intoxication and burn injury. Alcohol. 2019 11; 80:139-148.
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Iannitti RG, Napolioni V, Oikonomou V, De Luca A, Galosi C, Pariano M, Massi-Benedetti C, Borghi M, Puccetti M, Lucidi V, Colombo C, Fiscarelli E, Lass-Fl?rl C, Majo F, Cariani L, Russo M, Porcaro L, Ricciotti G, Ellemunter H, Ratclif L, De Benedictis FM, Talesa VN, Dinarello CA, van de Veerdonk FL, Romani L. IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis. Nat Commun. 2016 Mar 14; 7:10791.
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Gaba RC, Emmadi R, Parvinian A, Casadaban LC. Correlation of Doxorubicin Delivery and Tumor Necrosis after Drug-eluting Bead Transarterial Chemoembolization of Rabbit VX2 Liver Tumors. Radiology. 2016 09; 280(3):752-61.
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Yang B, Brahmbhatt A, Nieves Torres E, Thielen B, McCall DL, Engel S, Bansal A, Pandey MK, Dietz AB, Leof EB, DeGrado TR, Mukhopadhyay D, Misra S. Tracking and Therapeutic Value of Human Adipose Tissue-derived Mesenchymal Stem Cell Transplantation in Reducing Venous Neointimal Hyperplasia Associated with Arteriovenous Fistula. Radiology. 2016 May; 279(2):513-22.
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Nichols CE, Shepherd DL, Knuckles TL, Thapa D, Stricker JC, Stapleton PA, Minarchick VC, Erdely A, Zeidler-Erdely PC, Alway SE, Nurkiewicz TR, Hollander JM. Cardiac and mitochondrial dysfunction following acute pulmonary exposure to mountaintop removal mining particulate matter. Am J Physiol Heart Circ Physiol. 2015 Dec 15; 309(12):H2017-30.
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Charepalli V, Reddivari L, Radhakrishnan S, Vadde R, Agarwal R, Vanamala JK. Anthocyanin-containing purple-fleshed potatoes suppress colon tumorigenesis via elimination of colon cancer stem cells. J Nutr Biochem. 2015 Dec; 26(12):1641-9.
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Aherne CM, Saeedi B, Collins CB, Masterson JC, McNamee EN, Perrenoud L, Rapp CR, Curtis VF, Bayless A, Fletcher A, Glover LE, Evans CM, Jedlicka P, Furuta GT, de Zoeten EF, Colgan SP, Eltzschig HK. Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis. Mucosal Immunol. 2015 Nov; 8(6):1324-38.
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Ahmad F, Lal H, Zhou J, Vagnozzi RJ, Yu JE, Shang X, Woodgett JR, Gao E, Force T. Cardiomyocyte-specific deletion of Gsk3a mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure. J Am Coll Cardiol. 2014 Aug 19; 64(7):696-706.
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Bahr B, Galan HL, Arroyo JA. Decreased expression of phosphorylated placental heat shock protein 27 in human and ovine intrauterine growth restriction (IUGR). Placenta. 2014 Jun; 35(6):404-10.
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