 Transfection
"Transfection" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
| Descriptor ID |
D014162
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| MeSH Number(s) |
E05.393.350.810 G05.355.760.860
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transfection".
Below are MeSH descriptors whose meaning is more specific than "Transfection".
This graph shows the total number of publications written about "Transfection" by people in this website by year, and whether "Transfection" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 1 | 0 | 1 | | 1985 | 0 | 2 | 2 | | 1986 | 0 | 1 | 1 | | 1987 | 1 | 1 | 2 | | 1988 | 1 | 2 | 3 | | 1989 | 1 | 6 | 7 | | 1990 | 2 | 13 | 15 | | 1991 | 4 | 16 | 20 | | 1992 | 4 | 21 | 25 | | 1993 | 2 | 21 | 23 | | 1994 | 0 | 26 | 26 | | 1995 | 0 | 24 | 24 | | 1996 | 0 | 25 | 25 | | 1997 | 2 | 21 | 23 | | 1998 | 2 | 20 | 22 | | 1999 | 0 | 27 | 27 | | 2000 | 0 | 42 | 42 | | 2001 | 2 | 43 | 45 | | 2002 | 0 | 37 | 37 | | 2003 | 6 | 55 | 61 | | 2004 | 2 | 44 | 46 | | 2005 | 0 | 41 | 41 | | 2006 | 0 | 40 | 40 | | 2007 | 1 | 30 | 31 | | 2008 | 4 | 28 | 32 | | 2009 | 2 | 35 | 37 | | 2010 | 1 | 20 | 21 | | 2011 | 2 | 25 | 27 | | 2012 | 1 | 34 | 35 | | 2013 | 4 | 17 | 21 | | 2014 | 1 | 12 | 13 | | 2015 | 3 | 22 | 25 | | 2016 | 1 | 19 | 20 | | 2017 | 1 | 11 | 12 |
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Below are the most recent publications written about "Transfection" by people in Profiles.
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Zhang S, Hu Z, Tanji H, Jiang S, Das N, Li J, Sakaniwa K, Jin J, Bian Y, Ohto U, Shimizu T, Yin H. Small-molecule inhibition of TLR8 through stabilization of its resting state. Nat Chem Biol. 2018 Jan; 14(1):58-64.
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McNally KE, Faulkner R, Steinberg F, Gallon M, Ghai R, Pim D, Langton P, Pearson N, Danson CM, Nägele H, Morris LL, Singla A, Overlee BL, Heesom KJ, Sessions R, Banks L, Collins BM, Berger I, Billadeau DD, Burstein E, Cullen PJ. Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling. Nat Cell Biol. 2017 Oct; 19(10):1214-1225.
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Mura CV, Delgado R, Delgado MG, Restrepo D, Bacigalupo J. A CLCA regulatory protein present in the chemosensory cilia of olfactory sensory neurons induces a Ca2+-activated Cl- current when transfected into HEK293. BMC Neurosci. 2017 Aug 11; 18(1):61.
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Kästle M, Bartel S, Geillinger-Kästle K, Irmler M, Beckers J, Ryffel B, Eickelberg O, Krauss-Etschmann S. microRNA cluster 106a~363 is involved in T helper 17 cell differentiation. Immunology. 2017 11; 152(3):402-413.
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Bitler BG, Wu S, Park PH, Hai Y, Aird KM, Wang Y, Zhai Y, Kossenkov AV, Vara-Ailor A, Rauscher FJ, Zou W, Speicher DW, Huntsman DG, Conejo-Garcia JR, Cho KR, Christianson DW, Zhang R. ARID1A-mutated ovarian cancers depend on HDAC6 activity. Nat Cell Biol. 2017 08; 19(8):962-973.
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Goodell DJ, Zaegel V, Coultrap SJ, Hell JW, Bayer KU. DAPK1 Mediates LTD by Making CaMKII/GluN2B Binding LTP Specific. Cell Rep. 2017 06 13; 19(11):2231-2243.
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Li F, Song R, Ao L, Reece TB, Cleveland JC, Dong N, Fullerton DA, Meng X. ADAMTS5 Deficiency in Calcified Aortic Valves Is Associated With Elevated Pro-Osteogenic Activity in Valvular Interstitial Cells. Arterioscler Thromb Vasc Biol. 2017 07; 37(7):1339-1351.
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Yang N, Leung EL, Liu C, Li L, Eguether T, Jun Yao XJ, Jones EC, Norris DA, Liu A, Clark RA, Roop DR, Pazour GJ, Shroyer KR, Chen J. INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma. Oncogene. 2017 08 31; 36(35):4997-5005.
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Potter H, Heller R. Transfection by Electroporation. Curr Protoc Immunol. 2017 Apr 03; 117:10.15.1-10.15.9.
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Wang X, Goodrich KJ, Gooding AR, Naeem H, Archer S, Paucek RD, Youmans DT, Cech TR, Davidovich C. Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines. Mol Cell. 2017 Mar 16; 65(6):1056-1067.e5.
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