Receptors, Prolactin
"Receptors, Prolactin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Labile proteins on or in prolactin-sensitive cells that bind prolactin initiating the cells' physiological response to that hormone. Mammary casein synthesis is one of the responses. The receptors are also found in placenta, liver, testes, kidneys, ovaries, and other organs and bind and respond to certain other hormones and their analogs and antagonists. This receptor is related to the growth hormone receptor.
Descriptor ID |
D011981
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MeSH Number(s) |
D12.776.543.750.720.600.710 D12.776.543.750.750.555.710 D12.776.543.750.750.660.350.725
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Concept/Terms |
Receptors, Prolactin- Receptors, Prolactin
- Prolactin Receptors
- Receptors, PRL
- PRL Receptors
- Prolactin Receptor
- Receptor, Prolactin
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Below are MeSH descriptors whose meaning is more general than "Receptors, Prolactin".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Prolactin [D12.776.543.750.720.600.710]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Prolactin [D12.776.543.750.750.555.710]
- Receptors, Pituitary Hormone [D12.776.543.750.750.660]
- Receptors, Gonadotropin [D12.776.543.750.750.660.350]
- Receptors, Prolactin [D12.776.543.750.750.660.350.725]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Prolactin".
This graph shows the total number of publications written about "Receptors, Prolactin" by people in this website by year, and whether "Receptors, Prolactin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 | 1999 | 1 | 0 | 1 | 2000 | 0 | 1 | 1 | 2011 | 1 | 0 | 1 | 2012 | 1 | 0 | 1 | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Prolactin" by people in Profiles.
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Roach CM, Bidne KL, Romoser MR, Ross JW, Baumgard LH, Keating AF. Impact of heat stress on prolactin-mediated ovarian JAK-STAT signaling in postpubertal gilts. J Anim Sci. 2022 Jul 01; 100(7).
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Tufa DM, Shank T, Yingst AM, Trahan GD, Shim S, Lake J, Woods R, Jones K, Verneris MR. Prolactin Acts on Myeloid Progenitors to Modulate SMAD7 Expression and Enhance Hematopoietic Stem Cell Differentiation into the NK Cell Lineage. Sci Rep. 2020 04 14; 10(1):6335.
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Fiorillo AA, Medler TR, Feeney YB, Wetz SM, Tommerdahl KL, Clevenger CV. The prolactin receptor transactivation domain is associated with steroid hormone receptor expression and malignant progression of breast cancer. Am J Pathol. 2013 Jan; 182(1):217-33.
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Fiorillo AA, Medler TR, Feeney YB, Liu Y, Tommerdahl KL, Clevenger CV. HMGN2 inducibly binds a novel transactivation domain in nuclear PRLr to coordinate Stat5a-mediated transcription. Mol Endocrinol. 2011 Sep; 25(9):1550-64.
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Garc?a-Mart?nez JM, Calcabrini A, Gonz?lez L, Mart?n-Forero E, Agull?-Ortu?o MT, Simon V, Watkin H, Anderson SM, Roche S, Mart?n-P?rez J. A non-catalytic function of the Src family tyrosine kinases controls prolactin-induced Jak2 signaling. Cell Signal. 2010 Mar; 22(3):415-26.
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Trott JF, Horigan KC, Gloviczki JM, Costa KM, Freking BA, Farmer C, Hayashi K, Spencer T, Morabito JE, Hovey RC. Tissue-specific regulation of porcine prolactin receptor expression by estrogen, progesterone, and prolactin. J Endocrinol. 2009 Jul; 202(1):153-66.
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Schwertfeger KL, Hunter S, Heasley LE, Levresse V, Leon RP, DeGregori J, Anderson SM. Prolactin stimulates activation of c-jun N-terminal kinase (JNK). Mol Endocrinol. 2000 Oct; 14(10):1592-602.
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Lee RC, Walters JA, Reyland ME, Anderson SM. Constitutive activation of the prolactin receptor results in the induction of growth factor-independent proliferation and constitutive activation of signaling molecules. J Biol Chem. 1999 Apr 09; 274(15):10024-34.
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Ganguly TC, O'Brien ML, Karpen SJ, Hyde JF, Suchy FJ, Vore M. Regulation of the rat liver sodium-dependent bile acid cotransporter gene by prolactin. Mediation of transcriptional activation by Stat5. J Clin Invest. 1997 Jun 15; 99(12):2906-14.
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