Endoribonucleases
"Endoribonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of enzymes that catalyze the endonucleolytic cleavage of RNA. It includes EC 3.1.26.-, EC 3.1.27.-, EC 3.1.30.-, and EC 3.1.31.-.
Descriptor ID |
D004722
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MeSH Number(s) |
D08.811.277.352.355.350 D08.811.277.352.700.350
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Endoribonucleases".
Below are MeSH descriptors whose meaning is more specific than "Endoribonucleases".
This graph shows the total number of publications written about "Endoribonucleases" by people in this website by year, and whether "Endoribonucleases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 | 1996 | 3 | 0 | 3 | 1997 | 1 | 0 | 1 | 1998 | 2 | 0 | 2 | 1999 | 1 | 0 | 1 | 2000 | 2 | 0 | 2 | 2001 | 1 | 1 | 2 | 2002 | 2 | 1 | 3 | 2003 | 2 | 0 | 2 | 2004 | 1 | 1 | 2 | 2005 | 0 | 1 | 1 | 2007 | 3 | 2 | 5 | 2008 | 2 | 1 | 3 | 2010 | 1 | 1 | 2 | 2011 | 2 | 0 | 2 | 2013 | 2 | 1 | 3 | 2014 | 3 | 0 | 3 | 2015 | 3 | 1 | 4 | 2016 | 1 | 1 | 2 | 2017 | 1 | 1 | 2 | 2019 | 2 | 0 | 2 | 2021 | 2 | 1 | 3 | 2022 | 0 | 1 | 1 | 2024 | 1 | 1 | 2 | 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Endoribonucleases" by people in Profiles.
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Youle RL, Lista MJ, Bouton C, Kunzelmann S, Wilson H, Cottee MA, Purkiss AG, Morris ER, Neil SJD, Taylor IA, Swanson CM. Structural and functional characterization of the extended-diKH domain from the antiviral endoribonuclease KHNYN. J Biol Chem. 2025 Apr; 301(4):108336.
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Oguh AU, Haemmerle MW, Sen S, Rozo AV, Shrestha S, Cartailler JP, Fazelinia H, Ding H, Preza S, Yang J, Yang X, Sussel L, Alvarez-Dominguez JR, Doliba N, Spruce LA, Arrojo E Drigo R, Stoffers DA. E3 ligase substrate adaptor SPOP fine-tunes the UPR of pancreatic ? cells. Genes Dev. 2025 Feb 03; 39(3-4):261-279.
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Murthy A, Rodriguez LR, Dimopoulos T, Bui S, Iyer S, Chavez K, Tomer Y, Abraham V, Cooper C, Renner DM, Katzen JB, Bentley ID, Ghadiali SN, Englert JA, Weiss SR, Beers MF. Activation of alveolar epithelial ER stress by ?-coronavirus infection disrupts surfactant homeostasis in mice: implications for COVID-19 respiratory failure. Am J Physiol Lung Cell Mol Physiol. 2024 Aug 01; 327(2):L232-L249.
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Cooley JC, Redente EF. Getting the Timing Right: Controlling BCL-2 Inhibition as an Antifibrotic Therapy. Am J Respir Cell Mol Biol. 2024 Apr; 70(4):231-232.
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Cusic R, Watkins JM, Burke JM. Single-cell analysis of RNase L-mediated mRNA decay. Methods Enzymol. 2023; 692:157-175.
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Burke JM, Ripin N, Ferretti MB, St Clair LA, Worden-Sapper ER, Salgado F, Sawyer SL, Perera R, Lynch KW, Parker R. RNase L activation in the cytoplasm induces aberrant processing of mRNAs in the nucleus. PLoS Pathog. 2022 11; 18(11):e1010930.
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Sweet LA, Kuss-Duerkop SK, Keestra-Gounder AM. IRE1a-Driven Inflammation Promotes Clearance of Citrobacter rodentium Infection. Infect Immun. 2022 01 25; 90(1):e0048121.
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Burke JM, St Clair LA, Perera R, Parker R. SARS-CoV-2 infection triggers widespread host mRNA decay leading to an mRNA export block. RNA. 2021 11; 27(11):1318-1329.
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Canal B, Fujisawa R, McClure AW, Deegan TD, Wu M, Ulferts R, Weissmann F, Drury LS, Bertolin AP, Zeng J, Beale R, Howell M, Labib K, Diffley JFX. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease. Biochem J. 2021 07 16; 478(13):2465-2479.
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Burke JM, Gilchrist AR, Sawyer SL, Parker R. RNase L limits host and viral protein synthesis via inhibition of mRNA export. Sci Adv. 2021 06; 7(23).
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