 GTP-Binding Protein alpha Subunits, Gq-G11
"GTP-Binding Protein alpha Subunits, Gq-G11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of heterotrimeric GTP-binding protein alpha subunits that activate TYPE C PHOSPHOLIPASES dependent signaling pathways. The Gq-G11 part of the name is also spelled Gq/G11.
| Descriptor ID |
D043802
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| MeSH Number(s) |
D08.811.277.040.330.300.200.100.300 D12.644.360.360.100.300 D12.776.157.325.332.100.300 D12.776.476.375.100.300 D12.776.543.325.100.300
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| Concept/Terms |
GTP-Binding Protein alpha Subunits, Gq-G11- GTP-Binding Protein alpha Subunits, Gq-G11
- GTP Binding Protein alpha Subunits, Gq G11
- Gq-G11 G-Proteins
- G-Proteins, Gq-G11
- Gq G11 G Proteins
- Gq-G11 G-Protein Family
- Family, Gq-G11 G-Protein
- G-Protein Family, Gq-G11
- Gq G11 G Protein Family
- G-Protein, Gq-G11 alpha Family
- G Protein, Gq G11 alpha Family
- G-Protein, Gq-G11
- G Protein, Gq G11
- Gq-G11 G-Protein
GTP-Binding Protein alpha Subunit, Gq- GTP-Binding Protein alpha Subunit, Gq
- GTP Binding Protein alpha Subunit, Gq
- G alpha q Protein
- Galphaq Protein
- G-Protein, Gq
- G Protein, Gq
- Gq G-Protein
- G-Protein, Gq alpha Family
- G Protein, Gq alpha Family
- G alpha Protein q
- Gq Protein
GTP-Binding Protein alpha Subunit, G11- GTP-Binding Protein alpha Subunit, G11
- GTP Binding Protein alpha Subunit, G11
- G alpha11 Protein
- Protein, G alpha11
- alpha11 Protein, G
- Galpha11 Protein
- Protein, Galpha11
- G-Protein, G11
- G Protein, G11
- G11 G-Protein
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits, Gq-G11".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits, Gq-G11".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits, Gq-G11" by people in this website by year, and whether "GTP-Binding Protein alpha Subunits, Gq-G11" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2008 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTP-Binding Protein alpha Subunits, Gq-G11" by people in Profiles.
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Kanai SM, Garcia CR, Augustus MR, Sharafeldeen SA, Brooks EP, Sucharov J, Lencer ES, Nichols JT, Clouthier DE. The Gq/11 family of Ga subunits is necessary and sufficient for lower jaw development. Development. 2025 Apr 15; 152(8).
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Cvetkovic C, Patel R, Shetty A, Hogan MK, Anderson M, Basu N, Aghlara-Fotovat S, Ramesh S, Sardar D, Veiseh O, Ward ME, Deneen B, Horner PJ, Krencik R. Assessing Gq-GPCR-induced human astrocyte reactivity using bioengineered neural organoids. J Cell Biol. 2022 02 09; 221(4).
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Xie AX, Madayag A, Minton SK, McCarthy KD, Malykhina AP. Sensory satellite glial Gq-GPCR activation alleviates inflammatory pain via peripheral adenosine 1 receptor activation. Sci Rep. 2020 08 25; 10(1):14181.
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Singh P, Sharma P, Nakade UP, Sharma A, Gari M, Choudhury S, Shukla A, Garg SK. Endocannabinoid-mediated modulation of Gq protein-coupled receptor mediates vascular hyporeactivity to nor-adrenaline during polymicrobial sepsis. Pharmacol Rep. 2018 Dec; 70(6):1150-1157.
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Harraz OF, Longden TA, Dabertrand F, Hill-Eubanks D, Nelson MT. Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP2 depletion. Proc Natl Acad Sci U S A. 2018 04 10; 115(15):E3569-E3577.
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Kanai SM, Edwards AJ, Rurik JG, Osei-Owusu P, Blumer KJ. Proteolytic degradation of regulator of G protein signaling 2 facilitates temporal regulation of Gq/11 signaling and vascular contraction. J Biol Chem. 2017 11 24; 292(47):19266-19278.
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Chandran SS, Somerville RPT, Yang JC, Sherry RM, Klebanoff CA, Goff SL, Wunderlich JR, Danforth DN, Zlott D, Paria BC, Sabesan AC, Srivastava AK, Xi L, Pham TH, Raffeld M, White DE, Toomey MA, Rosenberg SA, Kammula US. Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study. Lancet Oncol. 2017 06; 18(6):792-802.
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Lim YH, Bacchiocchi A, Qiu J, Straub R, Bruckner A, Bercovitch L, Narayan D, McNiff J, Ko C, Robinson-Bostom L, Antaya R, Halaban R, Choate KA. GNA14 Somatic Mutation Causes Congenital and Sporadic Vascular Tumors by MAPK Activation. Am J Hum Genet. 2016 Aug 04; 99(2):443-50.
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Tilley DG, Zhu W, Myers VD, Barr LA, Gao E, Li X, Song J, Carter RL, Makarewich CA, Yu D, Troupes CD, Grisanti LA, Coleman RC, Koch WJ, Houser SR, Cheung JY, Feldman AM. ?-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling. Circulation. 2014 Nov 11; 130(20):1800-11.
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Avasarala S, Bikkavilli RK, Van Scoyk M, Zhang W, Lapite A, Hostetter L, Byers JT, Heasley LE, Sohn JW, Winn RA. Heterotrimeric G-protein, Ga16, is a critical downstream effector of non-canonical Wnt signaling and a potent inhibitor of transformed cell growth in non small cell lung cancer. PLoS One. 2013; 8(10):e76895.
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