 Bombesin
"Bombesin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tetradecapeptide originally obtained from the skins of toads Bombina bombina and B. variegata. It is also an endogenous neurotransmitter in many animals including mammals. Bombesin affects vascular and other smooth muscle, gastric secretion, and renal circulation and function.
| Descriptor ID |
D001839
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| MeSH Number(s) |
D06.472.699.100 D12.644.400.085 D12.644.548.100 D12.776.631.650.085 D20.888.033.137 D23.946.833.033.137
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Bombesin".
Below are MeSH descriptors whose meaning is more specific than "Bombesin".
This graph shows the total number of publications written about "Bombesin" by people in this website by year, and whether "Bombesin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bombesin" by people in Profiles.
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Bandara N, Stott Reynolds TJ, Schehr R, Bandari RP, Diebolder PJ, Krieger S, Xu J, Miao Y, Rogers BE, Smith CJ. Matched-pair, 86Y/90Y-labeled, bivalent RGD/bombesin antagonist, [RGD-Glu-[DO3A]-6-Ahx-RM2], as a potential theranostic agent for prostate cancer. Nucl Med Biol. 2018 Jul - Aug; 62-63:71-77.
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Stott Reynolds TJ, Schehr R, Liu D, Xu J, Miao Y, Hoffman TJ, Rold TL, Lewis MR, Smith CJ. Characterization and evaluation of DOTA-conjugated Bombesin/RGD-antagonists for prostate cancer tumor imaging and therapy. Nucl Med Biol. 2015 Feb; 42(2):99-108.
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Erickson CS, Barlow AJ, Pierre JF, Heneghan AF, Epstein ML, Kudsk KA, Gosain A. Colonic enteric nervous system analysis during parenteral nutrition. J Surg Res. 2013 Sep; 184(1):132-7.
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Subramaniam M, Bausch C, Twomey A, Andreeva S, Yoder BA, Chang L, Crapo JD, Pierce RA, Cuttitta F, Sunday ME. Bombesin-like peptides modulate alveolarization and angiogenesis in bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2007 Nov 01; 176(9):902-12.
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Chen X, Park R, Hou Y, Tohme M, Shahinian AH, Bading JR, Conti PS. microPET and autoradiographic imaging of GRP receptor expression with 64Cu-DOTA-[Lys3]bombesin in human prostate adenocarcinoma xenografts. J Nucl Med. 2004 Aug; 45(8):1390-7.
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Olincy A, Leonard S, Young DA, Sullivan B, Freedman R. Decreased bombesin peptide response to cigarette smoking in schizophrenia. Neuropsychopharmacology. 1999 Jan; 20(1):52-9.
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Scher H, Miller YE, Aguayo SM, Johnson KJ, Miller JE, McCray PB. Urinary bombesin-like peptide levels in infants and children with bronchopulmonary dysplasia and cystic fibrosis. Pediatr Pulmonol. 1998 Nov; 26(5):326-31.
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Cohen AJ, King TE, Gilman LB, Magill-Solc C, Miller YE. High expression of neutral endopeptidase in idiopathic diffuse hyperplasia of pulmonary neuroendocrine cells. Am J Respir Crit Care Med. 1998 Nov; 158(5 Pt 1):1593-9.
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Charlesworth A, Broad S, Rozengurt E. The bombesin/GRP receptor transfected into Rat-1 fibroblasts couples to phospholipase C activation, tyrosine phosphorylation of p125FAK and paxillin and cell proliferation. Oncogene. 1996 Mar 21; 12(6):1337-45.
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Mitchell FM, Heasley LE, Qian NX, Zamarripa J, Johnson GL. Differential modulation of bombesin-stimulated phospholipase C beta and mitogen-activated protein kinase activity by [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P. J Biol Chem. 1995 Apr 14; 270(15):8623-8.
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