 Adrenomedullin
"Adrenomedullin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 52-amino acid peptide with multi-functions. It was originally isolated from PHEOCHROMOCYTOMA and ADRENAL MEDULLA but is widely distributed throughout the body including lung and kidney tissues. Besides controlling fluid-electrolyte homeostasis, adrenomedullin is a potent vasodilator and can inhibit pituitary ACTH secretion.
| Descriptor ID |
D053607
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| MeSH Number(s) |
D06.472.699.077 D12.644.548.017
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| Concept/Terms |
PAMP(1-20)NH2- PAMP(1-20)NH2
- Proadrenomedullin N-Terminal 20 Peptide
- Proadrenomedullin N Terminal 20 Peptide
- Proadrenomedullin (1-20)
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Below are MeSH descriptors whose meaning is more general than "Adrenomedullin".
Below are MeSH descriptors whose meaning is more specific than "Adrenomedullin".
This graph shows the total number of publications written about "Adrenomedullin" by people in this website by year, and whether "Adrenomedullin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Adrenomedullin" by people in Profiles.
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Florin TA, Ambroggio L, Shah SS, Ruddy RM, Nylen ES, Balmert L. Urinary Proadrenomedullin and Disease Severity in Children With Suspected Community-acquired Pneumonia. Pediatr Infect Dis J. 2021 Dec 01; 40(12):1070-1075.
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Florin TA, Ambroggio L, Brokamp C, Zhang Y, Nylen ES, Rattan M, Crotty E, Belsky MA, Krueger S, Epperson TN, Kachelmeyer A, Ruddy RM, Shah SS. Proadrenomedullin Predicts Severe Disease in Children With Suspected Community-acquired Pneumonia. Clin Infect Dis. 2021 08 02; 73(3):e524-e530.
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Idrovo JP, Yang WL, Jacob A, Ajakaiye MA, Cheyuo C, Wang Z, Prince JM, Nicastro J, Coppa GF, Wang P. Combination of adrenomedullin with its binding protein accelerates cutaneous wound healing. PLoS One. 2015; 10(3):e0120225.
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Sena JA, Wang L, Pawlus MR, Hu CJ. HIFs enhance the transcriptional activation and splicing of adrenomedullin. Mol Cancer Res. 2014 May; 12(5):728-41.
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MacManus CF, Campbell EL, Keely S, Burgess A, Kominsky DJ, Colgan SP. Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization. FASEB J. 2011 Jun; 25(6):1856-64.
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