Transposases
"Transposases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that recombine DNA segments by a process which involves the formation of a synapse between two DNA helices, the cleavage of single strands from each DNA helix and the ligation of a DNA strand from one DNA helix to the other. The resulting DNA structure is called a Holliday junction which can be resolved by DNA REPLICATION or by HOLLIDAY JUNCTION RESOLVASES.
Descriptor ID |
D019895
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MeSH Number(s) |
D08.811.739.500.667 D08.811.913.696.445.825
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transposases".
Below are MeSH descriptors whose meaning is more specific than "Transposases".
This graph shows the total number of publications written about "Transposases" by people in this website by year, and whether "Transposases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 | 2014 | 2 | 1 | 3 | 2016 | 2 | 0 | 2 | 2020 | 0 | 1 | 1 | 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Transposases" by people in Profiles.
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Xu W, Yang W, Zhang Y, Chen Y, Hong N, Zhang Q, Wang X, Hu Y, Song K, Jin W, Chen X. ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells. Nat Methods. 2022 10; 19(10):1243-1249.
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Gupta A, Sasse SK, Berman R, Gruca MA, Dowell RD, Chu HW, Downey GP, Gerber AN. Integrated genomics approaches identify transcriptional mediators and epigenetic responses to Afghan desert particulate matter in small airway epithelial cells. Physiol Genomics. 2022 10 01; 54(10):389-401.
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Nagy D, Verheyen S, Wigby KM, Borovikov A, Sharkov A, Slegesky V, Larson A, Fagerberg C, Brasch-Andersen C, Kib?k M, Bader I, Hernan R, High FA, Chung WK, Schieving JH, Behunova J, Smogavec M, Laccone F, Witsch-Baumgartner M, Zobel J, Duba HC, Weis D. Genotype-Phenotype Comparison in POGZ-Related Neurodevelopmental Disorders by Using Clinical Scoring. Genes (Basel). 2022 01 15; 13(1).
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Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, Shen Y, He Y, Mackiewicz M, Pauli-Behn F, Williams BA, Mortazavi A, Keller CA, Zhang XO, Elhajjajy SI, Huey J, Dickel DE, Snetkova V, Wei X, Wang X, Rivera-Mulia JC, Rozowsky J, Zhang J, Chhetri SB, Zhang J, Victorsen A, White KP, Visel A, Yeo GW, Burge CB, L?cuyer E, Gilbert DM, Dekker J, Rinn J, Mendenhall EM, Ecker JR, Kellis M, Klein RJ, Noble WS, Kundaje A, Guig? R, Farnham PJ, Cherry JM, Myers RM, Ren B, Graveley BR, Gerstein MB, Pennacchio LA, Snyder MP, Bernstein BE, Wold B, Hardison RC, Gingeras TR, Stamatoyannopoulos JA, Weng Z. Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature. 2020 07; 583(7818):699-710.
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Harmacek LD, Patel P, Woolaver R, Reinhardt RL, O'Connor BP. Library Preparation for ATAC-Sequencing of Mouse CD4+ T Cells Isolated from the Lung and Lymph Nodes After Helminth Infection. Methods Mol Biol. 2018; 1799:327-340.
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Morris ER, Grey H, McKenzie G, Jones AC, Richardson JM. A bend, flip and trap mechanism for transposon integration. Elife. 2016 05 25; 5.
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Deniger DC, Pasetto A, Tran E, Parkhurst MR, Cohen CJ, Robbins PF, Cooper LJ, Rosenberg SA. Stable, Nonviral Expression of Mutated Tumor Neoantigen-specific T-cell Receptors Using the Sleeping Beauty Transposon/Transposase System. Mol Ther. 2016 06; 24(6):1078-1089.
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Forsberg KJ, Patel S, Gibson MK, Lauber CL, Knight R, Fierer N, Dantas G. Bacterial phylogeny structures soil resistomes across habitats. Nature. 2014 May 29; 509(7502):612-6.
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Trubitsyna M, Morris ER, Finnegan DJ, Richardson JM. Biochemical characterization and comparison of two closely related active mariner transposases. Biochemistry. 2014 Feb 04; 53(4):682-9.
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Wolkowicz UM, Morris ER, Robson M, Trubitsyna M, Richardson JM. Structural basis of Mos1 transposase inhibition by the anti-retroviral drug Raltegravir. ACS Chem Biol. 2014 Mar 21; 9(3):743-51.
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