 Choline-Phosphate Cytidylyltransferase
"Choline-Phosphate Cytidylyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the transfer of cytidylate (CMP) to choline phosphate to form CDPcholine. It is the rate-limiting enzyme in the choline pathway for the biosynthesis of phosphatidylcholine. Its activity is increased by glucocorticoids. EC 2.7.7.15.
| Descriptor ID |
D019916
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| MeSH Number(s) |
D08.811.913.696.445.184
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| Concept/Terms |
Choline-Phosphate Cytidylyltransferase- Choline-Phosphate Cytidylyltransferase
- Choline Phosphate Cytidylyltransferase
- Cytidylyltransferase, Choline-Phosphate
- CTP Phosphocholine Cytidylyl-Transferase
- CTP Phosphocholine Cytidylyl Transferase
- Cytidylyl-Transferase, CTP Phosphocholine
- Phosphocholine Cytidylyl-Transferase, CTP
- Phosphorylcholine Cytidyl Transferase
- Cytidyl Transferase, Phosphorylcholine
- Transferase, Phosphorylcholine Cytidyl
- CTP Phosphorylcholine Cytidyltransferase
- Cytidyltransferase, CTP Phosphorylcholine
- Phosphorylcholine Cytidyltransferase, CTP
- Phosphocholine Cytidyltransferase
- Cytidyltransferase, Phosphocholine
- CDP-Choline Synthetase
- CDP Choline Synthetase
- Synthetase, CDP-Choline
- CTP Phosphocholine Cytidylyltransferase
- Cytidylyltransferase, CTP Phosphocholine
- Phosphocholine Cytidylyltransferase, CTP
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Below are MeSH descriptors whose meaning is more general than "Choline-Phosphate Cytidylyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Choline-Phosphate Cytidylyltransferase".
This graph shows the total number of publications written about "Choline-Phosphate Cytidylyltransferase" by people in this website by year, and whether "Choline-Phosphate Cytidylyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Choline-Phosphate Cytidylyltransferase" by people in Profiles.
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Vaezi AE, Bepler G, Bhagwat NR, Malysa A, Rubatt JM, Chen W, Hood BL, Conrads TP, Wang L, Kemp CE, Niedernhofer LJ. Choline phosphate cytidylyltransferase-a is a novel antigen detected by the anti-ERCC1 antibody 8F1 with biomarker value in patients with lung and head and neck squamous cell carcinomas. Cancer. 2014 Jun 15; 120(12):1898-907.
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Darpolor MM, Kennealey PT, Le HC, Zakian KL, Ackerstaff E, Rizwan A, Chen JH, Sambol EB, Schwartz GK, Singer S, Koutcher JA. Preclinical study of treatment response in HCT-116 cells and xenografts with (1) H-decoupled (31) P MRS. NMR Biomed. 2011 Nov; 24(9):1159-68.
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Dobrzyn A, Dobrzyn P, Miyazaki M, Sampath H, Chu K, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases CTP:choline cytidylyltransferase translocation into the membrane and enhances phosphatidylcholine synthesis in liver. J Biol Chem. 2005 Jun 17; 280(24):23356-62.
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