HIV Long Terminal Repeat
"HIV Long Terminal Repeat" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.
Descriptor ID |
D016325
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MeSH Number(s) |
G02.111.570.080.708.850.400 G05.360.080.708.850.400
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Concept/Terms |
HIV Long Terminal Repeat- HIV Long Terminal Repeat
- LTR, Human Immunodeficiency Virus
- Human Immunodeficiency Virus LTR
- Long Terminal Repeat, HIV
- Human Immunodeficiency Virus Long Terminal Repeat
Trans-Acting Responsive Region, HIV- Trans-Acting Responsive Region, HIV
- Trans Acting Responsive Region, HIV
- HIV Trans-Acting Responsive Region
- HIV Trans Acting Responsive Region
- Trans-Activation Responsive Element, HIV
- Trans Activation Responsive Element, HIV
- Trans-Activation Responsive Region, HIV
- Trans Activation Responsive Region, HIV
- TAR Element, HIV
- HIV TAR Element
- HIV TAR Elements
- TAR Elements, HIV
Sp1-Binding Site, HIV- Sp1-Binding Site, HIV
- Sp1 Binding Site, HIV
- HIV Sp1-Binding Site
- HIV Sp1 Binding Site
- HIV Sp1-Binding Sites
- Sp1-Binding Sites, HIV
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Below are MeSH descriptors whose meaning is more general than "HIV Long Terminal Repeat".
Below are MeSH descriptors whose meaning is more specific than "HIV Long Terminal Repeat".
This graph shows the total number of publications written about "HIV Long Terminal Repeat" by people in this website by year, and whether "HIV Long Terminal Repeat" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 | 2003 | 2 | 0 | 2 | 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "HIV Long Terminal Repeat" by people in Profiles.
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Zhou J, Lazar D, Li H, Xia X, Satheesan S, Charlins P, O'Mealy D, Akkina R, Saayman S, Weinberg MS, Rossi JJ, Morris KV. Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1. Theranostics. 2018; 8(6):1575-1590.
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Han Y, Wang S, Zhang Z, Ma X, Li W, Zhang X, Deng J, Wei H, Li Z, Zhang XE, Cui Z. In vivo imaging of protein-protein and RNA-protein interactions using novel far-red fluorescence complementation systems. Nucleic Acids Res. 2014 Jul; 42(13):e103.
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Musselman C, Pitt SW, Gulati K, Foster LL, Andricioaei I, Al-Hashimi HM. Impact of static and dynamic A-form heterogeneity on the determination of RNA global structural dynamics using NMR residual dipolar couplings. J Biomol NMR. 2006 Dec; 36(4):235-49.
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Giffin MJ, Stroud JC, Bates DL, von Koenig KD, Hardin J, Chen L. Structure of NFAT1 bound as a dimer to the HIV-1 LTR kappa B element. Nat Struct Biol. 2003 Oct; 10(10):800-6.
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Gomes N, Garber ME, Jones KA. Techniques to analyze the HIV-1 Tat and TAR RNA-dependent recruitment and activation of the cyclin T1: CDK9 (P-TEFb) transcription elongation factor. Methods Enzymol. 2003; 371:324-36.
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Corboy JR, Garl PJ. HIV-1 LTR DNA sequence variation in brain-derived isolates. J Neurovirol. 1997 Oct; 3(5):331-41.
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Corboy JR, Buzy JM, Zink MC, Clements JE. Expression directed from HIV long terminal repeats in the central nervous system of transgenic mice. Science. 1992 Dec 11; 258(5089):1804-8.
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Batey RT, Inada M, Kujawinski E, Puglisi JD, Williamson JR. Preparation of isotopically labeled ribonucleotides for multidimensional NMR spectroscopy of RNA. Nucleic Acids Res. 1992 Sep 11; 20(17):4515-23.
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Vickers T, Baker BF, Cook PD, Zounes M, Buckheit RW, Germany J, Ecker DJ. Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element. Nucleic Acids Res. 1991 Jun 25; 19(12):3359-68.
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Harrison GS, Maxwell F, Long CJ, Rosen CA, Glode LM, Maxwell IH. Activation of a diphtheria toxin A gene by expression of human immunodeficiency virus-1 Tat and Rev proteins in transfected cells. Hum Gene Ther. 1991; 2(1):53-60.
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