 Macrophage Activation
"Macrophage Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.
| Descriptor ID |
D008262
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| MeSH Number(s) |
G12.287.500
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| Concept/Terms |
Macrophage Activation- Macrophage Activation
- Activation, Macrophage
- Activations, Macrophage
- Macrophage Activations
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Below are MeSH descriptors whose meaning is more general than "Macrophage Activation".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Activation".
This graph shows the total number of publications written about "Macrophage Activation" by people in this website by year, and whether "Macrophage Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 1 | 2 | | 1991 | 1 | 2 | 3 | | 1992 | 1 | 1 | 2 | | 1993 | 0 | 3 | 3 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 4 | 4 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 2000 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 3 | 2 | 5 | | 2006 | 1 | 3 | 4 | | 2007 | 3 | 2 | 5 | | 2008 | 3 | 3 | 6 | | 2009 | 2 | 1 | 3 | | 2010 | 3 | 0 | 3 | | 2011 | 2 | 2 | 4 | | 2012 | 4 | 3 | 7 | | 2013 | 3 | 4 | 7 | | 2014 | 4 | 2 | 6 | | 2015 | 1 | 4 | 5 | | 2016 | 0 | 3 | 3 | | 2017 | 3 | 1 | 4 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Macrophage Activation" by people in Profiles.
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Svedberg FR, Brown SL, Krauss MZ, Campbell L, Sharpe C, Clausen M, Howell GJ, Clark H, Madsen J, Evans CM, Sutherland TE, Ivens AC, Thornton DJ, Grencis RK, Hussell T, Cunoosamy DM, Cook PC, MacDonald AS. The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation. Nat Immunol. 2019 05; 20(5):571-580.
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Anttila JE, Albert K, Wires ES, Mätlik K, Loram LC, Watkins LR, Rice KC, Wang Y, Harvey BK, Airavaara M. Post-stroke Intranasal (+)-Naloxone Delivery Reduces Microglial Activation and Improves Behavioral Recovery from Ischemic Injury. eNeuro. 2018 Mar-Apr; 5(2).
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Quick ED, Seitz S, Clarke P, Tyler KL. Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection. J Virol. 2017 11 15; 91(22).
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Coakley G, McCaskill JL, Borger JG, Simbari F, Robertson E, Millar M, Harcus Y, McSorley HJ, Maizels RM, Buck AH. Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity. Cell Rep. 2017 05 23; 19(8):1545-1557.
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Eshleman EM, Delgado C, Kearney SJ, Friedman RS, Lenz LL. Down regulation of macrophage IFNGR1 exacerbates systemic L. monocytogenes infection. PLoS Pathog. 2017 May; 13(5):e1006388.
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Pugliese SC, Kumar S, Janssen WJ, Graham BB, Frid MG, Riddle SR, El Kasmi KC, Stenmark KR. A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension. J Immunol. 2017 06 15; 198(12):4802-4812.
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Sultana F, Neog MK, Rasool M. Withaferin-A, a steroidal lactone encapsulated mannose decorated liposomes ameliorates rheumatoid arthritis by intriguing the macrophage repolarization in adjuvant-induced arthritic rats. Colloids Surf B Biointerfaces. 2017 Jul 01; 155:349-365.
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Carias AM, Allen SA, Fought AJ, Kotnik Halavaty K, Anderson MR, Jimenez ML, McRaven MD, Gioia CJ, Henning TR, Kersh EN, Smith JM, Pereira LE, Butler K, McNicholl SJ, Hendry RM, Kiser PF, Veazey RS, Hope TJ. Increases in Endogenous or Exogenous Progestins Promote Virus-Target Cell Interactions within the Non-human Primate Female Reproductive Tract. PLoS Pathog. 2016 09; 12(9):e1005885.
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Shults JA, Curtis BJ, Boe DM, Ramirez L, Kovacs EJ. Ethanol intoxication prolongs post-burn pulmonary inflammation: role of alveolar macrophages. J Leukoc Biol. 2016 11; 100(5):1037-1045.
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Albright JM, Dunn RC, Shults JA, Boe DM, Afshar M, Kovacs EJ. Advanced Age Alters Monocyte and Macrophage Responses. Antioxid Redox Signal. 2016 11 20; 25(15):805-815.
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