 Antigens, Polyomavirus Transforming
"Antigens, Polyomavirus Transforming" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle.
| Descriptor ID |
D000952
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| MeSH Number(s) |
D12.776.624.664.520.090 D12.776.964.700.090 D23.050.285.062.090 D23.050.327.062.090
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| Concept/Terms |
Antigens, Polyomavirus Transforming- Antigens, Polyomavirus Transforming
- Polyomavirus Tumor Antigens
- Antigens, Polyomavirus Tumor
- Tumor Antigens, Polyomavirus
- Polyomavirus Transforming Antigens
- Transforming Antigens, Polyomavirus
SV40 T Proteins- SV40 T Proteins
- Proteins, SV40 T
- T Proteins, SV40
- SV40 T Antigens
- Antigens, SV40 T
- T Antigens, SV40
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Below are MeSH descriptors whose meaning is more general than "Antigens, Polyomavirus Transforming".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Neoplasm Proteins [D12.776.624]
- Oncogene Proteins [D12.776.624.664]
- Oncogene Proteins, Viral [D12.776.624.664.520]
- Antigens, Polyomavirus Transforming [D12.776.624.664.520.090]
- Viral Proteins [D12.776.964]
- Oncogene Proteins, Viral [D12.776.964.700]
- Antigens, Polyomavirus Transforming [D12.776.964.700.090]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Neoplasm [D23.050.285]
- Antigens, Viral, Tumor [D23.050.285.062]
- Antigens, Polyomavirus Transforming [D23.050.285.062.090]
- Antigens, Viral [D23.050.327]
- Antigens, Viral, Tumor [D23.050.327.062]
- Antigens, Polyomavirus Transforming [D23.050.327.062.090]
Below are MeSH descriptors whose meaning is more specific than "Antigens, Polyomavirus Transforming".
This graph shows the total number of publications written about "Antigens, Polyomavirus Transforming" by people in this website by year, and whether "Antigens, Polyomavirus Transforming" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 2 | 0 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antigens, Polyomavirus Transforming" by people in Profiles.
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Dixon BP, Henry J, Siroky BJ, Chu A, Groen PA, Bissler JJ. Cell cycle control and DNA damage response of conditionally immortalized urothelial cells. PLoS One. 2011 Jan 28; 6(1):e16595.
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Chen P, O'Neal JF, Ebelt ND, Cantrell MA, Mitra S, Nasrazadani A, Vandenbroek TL, Heasley LE, Van Den Berg CL. Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model. PLoS One. 2010 May 03; 5(5):e10443.
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Seluanov A, Hine C, Azpurua J, Feigenson M, Bozzella M, Mao Z, Catania KC, Gorbunova V. Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19352-7.
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Lu X, Arbiser JL, West J, Hoedt-Miller M, Sheridan A, Govindarajan B, Harral JW, Rodman DM, Fouty B. Tumor necrosis factor-related apoptosis-inducing ligand can induce apoptosis in subsets of premalignant cells. Am J Pathol. 2004 Nov; 165(5):1613-20.
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Gai D, Zhao R, Li D, Finkielstein CV, Chen XS. Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen. Cell. 2004 Oct 01; 119(1):47-60.
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Li D, Zhao R, Lilyestrom W, Gai D, Zhang R, DeCaprio JA, Fanning E, Jochimiak A, Szakonyi G, Chen XS. Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen. Nature. 2003 May 29; 423(6939):512-8.
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Nogues G, Kadener S, Cramer P, Bentley D, Kornblihtt AR. Transcriptional activators differ in their abilities to control alternative splicing. J Biol Chem. 2002 Nov 08; 277(45):43110-4.
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Kumar TR, Graham KE, Asa SL, Low MJ. Simian virus 40 T antigen-induced gonadotroph adenomas: a model of human null cell adenomas. Endocrinology. 1998 Jul; 139(7):3342-51.
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Clarkson ED, Rosa FG, Edwards-Prasad J, Weiland DA, Witta SE, Freed CR, Prasad KN. Improvement of neurological deficits in 6-hydroxydopamine-lesioned rats after transplantation with allogeneic simian virus 40 large tumor antigen gene-induced immortalized dopamine cells. Proc Natl Acad Sci U S A. 1998 Feb 03; 95(3):1265-70.
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Clarkson ED, La Rosa FG, Edwards-Prasad J, Kumar S, Kumar A, Cole W, Freed CR, Prasad KN. Brain contains inhibiting factors specific to the large T-antigen gene. Cancer Lett. 1998 Jan 09; 122(1-2):31-6.
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