 Parathyroid Hormone-Related Protein
"Parathyroid Hormone-Related Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activities that are similar to PARATHYROID HORMONE. It does not circulate in appreciable amounts in normal subjects, but rather exerts its biological actions locally. Overexpression of parathyroid hormone-related protein by tumor cells results in humoral calcemia of malignancy.
| Descriptor ID |
D044162
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| MeSH Number(s) |
D06.472.699.591 D12.644.276.908 D12.644.548.588 D12.776.467.890 D23.529.890
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| Concept/Terms |
Parathyroid Hormone-Related Protein- Parathyroid Hormone-Related Protein
- Hormone-Related Protein, Parathyroid
- Parathyroid Hormone Related Protein
- Parathyroid Hormone-Like Protein
- Parathyroid Hormone Like Protein
- Parathyroid Hormone-Related Peptide
- Parathyroid Hormone Related Peptide
- PTHrP
- Tumor Hypercalcemic Factor
- Hypercalcemic Factor, Tumor
- Hypercalcemic Hormone of Malignancy
- PTH Like Tumor Factor
- PTH-Like Protein
- PTH Like Protein
- Parathyroid Hormone Like Tumor Factor
- PTH-Related Peptide
- PTH Related Peptide
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Below are MeSH descriptors whose meaning is more general than "Parathyroid Hormone-Related Protein".
Below are MeSH descriptors whose meaning is more specific than "Parathyroid Hormone-Related Protein".
This graph shows the total number of publications written about "Parathyroid Hormone-Related Protein" by people in this website by year, and whether "Parathyroid Hormone-Related Protein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 2 | 2 | | 2002 | 0 | 3 | 3 | | 2003 | 0 | 3 | 3 | | 2004 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2013 | 1 | 1 | 2 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Parathyroid Hormone-Related Protein" by people in Profiles.
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McClung MR, Rothman MS, Lewiecki EM, Hanley DA, Harris ST, Miller PD, Kendler DL. The role of osteoanabolic agents in the management of patients with osteoporosis. Postgrad Med. 2022 Aug; 134(6):541-551.
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Zhang H, Yu C, Dai J, Keller JM, Hua A, Sottnik JL, Shelley G, Hall CL, Park SI, Yao Z, Zhang J, McCauley LK, Keller ET. Parathyroid hormone-related protein inhibits DKK1 expression through c-Jun-mediated inhibition of ?-catenin activation of the DKK1 promoter in prostate cancer. Oncogene. 2014 May 08; 33(19):2464-77.
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Sottnik JL, Keller ET. Understanding and targeting osteoclastic activity in prostate cancer bone metastases. Curr Mol Med. 2013 May; 13(4):626-39.
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Bian L, Zhai DY, Tous E, Rai R, Mauck RL, Burdick JA. Enhanced MSC chondrogenesis following delivery of TGF-?3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo. Biomaterials. 2011 Sep; 32(27):6425-34.
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Thudi NK, Shu ST, Martin CK, Lanigan LG, Nadella MV, Van Bokhoven A, Werbeck JL, Simmons JK, Murahari S, Kisseberth WC, Breen M, Williams C, Chen CS, McCauley LK, Keller ET, Rosol TJ. Development of a brain metastatic canine prostate cancer cell line. Prostate. 2011 Sep; 71(12):1251-63.
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Washino S, Terauchi F, Matsuzaki A, Kobayashi Y. [Two cases of squamous cell carcinoma of upper urinary tract with hypercalcemia]. Nihon Hinyokika Gakkai Zasshi. 2008 Sep; 99(6):703-8.
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LeRoy BE, Thudi NK, Nadella MV, Toribio RE, Tannehill-Gregg SH, van Bokhoven A, Davis D, Corn S, Rosol TJ. New bone formation and osteolysis by a metastatic, highly invasive canine prostate carcinoma xenograft. Prostate. 2006 Aug 01; 66(11):1213-22.
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Dong Y, Drissi H, Chen M, Chen D, Zuscik MJ, Schwarz EM, O'Keefe RJ. Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-beta. J Cell Biochem. 2005 Aug 01; 95(5):1057-68.
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Li TF, Dong Y, Ionescu AM, Rosier RN, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H. Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway. Exp Cell Res. 2004 Sep 10; 299(1):128-36.
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Ionescu AM, Drissi H, Schwarz EM, Kato M, Puzas JE, McCance DJ, Rosier RN, Zuscik MJ, O'Keefe RJ. CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter. J Cell Physiol. 2004 Mar; 198(3):428-40.
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